Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rachel E. Fontana"'
Autor:
Megan E. Honeywell, Marie S. Isidor, Nicholas W. Harper, Rachel E. Fontana, Peter Cruz- Gordillo, Sydney A. Porto, Cameron S. Fraser, Kristopher A. Sarosiek, David A. Guertin, Jessica B. Spinelli, Michael J. Lee
SUMMARYDNA damage can activate apoptotic and non-apoptotic forms of cell death; however, it remains unclear what features dictate which type of cell death is activated. We report that p53 controls the choice between apoptotic and non-apoptotic death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7671bdea81b1ab74d4adda00543997c7
https://doi.org/10.1101/2023.01.17.524444
https://doi.org/10.1101/2023.01.17.524444
Autor:
Rachel E. Fontana, Hannah R. Schwartz, Michael J. Lee, Megan E. Honeywell, Ryan Richards, Anna J. Joyce
Publikováno v:
Cell reports
SUMMARY When evaluating anti-cancer drugs, two different measurements are used: relative viability, which scores an amalgam of proliferative arrest and cell death, and fractional viability, which specifically scores the degree of cell killing. We qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30b0f1c6a9a62193146ba1a169c865f
https://doi.org/10.1101/2020.02.26.966689
https://doi.org/10.1101/2020.02.26.966689
Autor:
Julian Schlegel, Mahmoud Moustafa, Katharina Kriegsmann, Katrin Rein, Jin Qi, Guozhong Qin, Cheng Zhou, Jennifer Furkel, Mark Kriegsmann, Amir Abdollahi, Maximilian Knoll, Feng Jiang, Sayed-Mohammad Hasheminasab, Adam Lazorchak, Juergen Debus, Chunxiao Xu, Rachel E. Fontana, Bo Marelli, Zili Tang, Damir Krunic, Yan Lan, George Locke, Carmen Klein, Molly H. Jenkins, Tsz-Lun Yeung, Huakui Yu, Sarah Meister, Kin-Ming Lo, Melissa G. Derner, Christian Schwager
Publikováno v:
Cancer Cell. 39:1388-1403.e10
Summary Localized radiotherapy (RT) induces an immunogenic antitumor response that is in part counterbalanced by activation of immune evasive and tissue remodeling processes, e.g., via upregulation of programmed cell death-ligand 1 (PD-L1) and transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c9ce4655319e5c8e432661a57b50307
https://doi.org/10.1016/j.ccell.2021.08.008
https://doi.org/10.1016/j.ccell.2021.08.008
Publikováno v:
Progress in Oceanography. 142:1-16
Zooplankton abundance and species composition provide information on environmental variability in the ocean. While zooplankton time series span the west coast of North America, less data exist off north-central California. Here, we investigated a zoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e312fc224cc90f6ab6189b06fbcdc5d
https://doi.org/10.1016/j.pocean.2016.01.004
https://doi.org/10.1016/j.pocean.2016.01.004
Autor:
Vivian M. Hernández, Aroop Sircar, Helen Sabzevari, Jin Qi, Dong Zhang, Guozhong Qin, Chunxiao Xu, Bo Marelli, Yan Lan, Huakui Yu, Molly H. Jenkins, Laszlo Radvanyi, Kin-Ming Lo, George Locke, Rachel E. Fontana, Amit M. Deshpande, Kenneth W. Hance
Publikováno v:
Science Translational Medicine. 10
Antibodies targeting immune checkpoints are emerging as potent and viable cancer therapies, but not all patients respond to these as single agents. Concurrently targeting additional immunosuppressive pathways is a promising approach to enhance immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c111cfdc6ef188a2ad09dbd38f37fab6
https://doi.org/10.1126/scitranslmed.aan5488
https://doi.org/10.1126/scitranslmed.aan5488
Autor:
Grace Ha, R. Eliot Crafton, Rachel E. Fontana, Chela J. Zabin, Jae R. Pasari, Edwin D. Grosholz, Susan L. Williams
Publikováno v:
Management of Biological Invasions. 6:13-29
The trade in marine and estuarine ornamental species has resulted in the introductions of some of the world’s worst invasive species, including the seaweed Caulerpa taxifolia and the lionfish Pterois volitans. We conducted an analysis of the histor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4df07f295ba0884d1ec67c9c303cdb8
https://doi.org/10.3391/mbi.2015.6.1.02
https://doi.org/10.3391/mbi.2015.6.1.02
Autor:
Susan L. Williams, Edwin D. Grosholz, R. Eliot Crafton, Chela J. Zabin, Jae R. Pasari, Rachel E. Fontana
Publikováno v:
Biological Invasions. 17:1471-1484
Although ballast water and hull fouling are widely recognized as important vectors for marine invasions, the risk posed by commercial aquaculture remains poorly quantified. To understand the importance of aquaculture as an invasion vector in Californ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aba1b4b887294eb9e899dc27d977363
https://doi.org/10.1007/s10530-014-0808-9
https://doi.org/10.1007/s10530-014-0808-9
Autor:
R. Eliot Crafton, Ian C. Davidson, Jae R. Pasari, Rachel E. Fontana, Chela J. Zabin, A. Whitman Miller, Susan L. Williams, Gregory M. Ruiz, James T. Carlton, Edwin D. Grosholz, Gail V. Ashton
Publikováno v:
BioScience. 63:952-966
Invasive species remain a major environmental problem in the world's oceans. Managing the vectors of introduction is the most effective means of mitigating this problem, but current risk assessments and management strategies are largely focused on sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceae3ab82ecb52f47f55a61d73c72dd1
https://doi.org/10.1525/bio.2013.63.12.8
https://doi.org/10.1525/bio.2013.63.12.8
Autor:
Carol A. Keiper, Amber I. Szoboszlai, Annaliese Hettinger, Rachel E. Fontana, Susanne M. Brander, Sarah A. Gravem, Meghan E. Marrero, Tawny M. Mata, Jessica R. Bean
Publikováno v:
The American Biology Teacher. 73:474-478
The accumulation of plastic in the oceans is an ever-growing environmental concern. Plastic debris is a choking and entanglement hazard for wildlife; plastics also leach toxic compounds into organisms and ecosystems. Educating students about the mari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba23d713480810f2228318228aeb475
https://doi.org/10.1525/abt.2011.73.8.9
https://doi.org/10.1525/abt.2011.73.8.9
Autor:
Yun Wu, Elizabeth Trehu, Heather A. Hirsch, Tong Zi, Rachel E. Fontana, Elizabeth A. Mittendorf, Emma Lees, David J. Lee, Alexander Needham, Edward C. Stack, Jason Reeves, Deborah A. Law
Publikováno v:
Cancer Research. 78:1678-1678
ICOS (Inducible CO-Stimulator of T cells) is a co-stimulatory molecule expressed primarily on T lymphocytes. ICOS was prioritized as a target of interest based on nonclinical and clinical data that identified ICOS as a potentially key molecule in pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d444663b6be4020161200cee42a8c9a9
https://doi.org/10.1158/1538-7445.am2018-1678
https://doi.org/10.1158/1538-7445.am2018-1678