Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Rachel E. Ellsworth"'
Autor:
Hikmat Abdel-Razeq, Baha' Sharaf, Hira Bani Hani, Ramiz Abu Hijlih, Mais Alkyam, Khansa Al-Azzam, Shatha Elemian, Abdelghani Tbakhi, Areej Al-Atary, Rachel E. Ellsworth, Emily M. Russell, Edward D. Esplin, Malek Horani, Zeidan Zeidan, Abdulla Alzibdeh, Brandie Heald, Sarah M. Nielsen, Robert L. Nussbaum
Publikováno v:
JCO Global Oncology, Vol , Iss 10 (2024)
PURPOSEGermline genetic testing (GGT) significantly affects cancer care. While universal testing has been studied in Western societies, less is known about adoption elsewhere.MATERIALS AND METHODSIn this study, 3,319 unselected, pan-cancer Jordanian
Externí odkaz:
https://doaj.org/article/7d5166b37872449cb505823fc6b1095c
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/f92545ea7e9549909c39080ac94360ee
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundDuctal carcinoma in situ (DCIS) is a malignant, yet pre-invasive disease of the breast. While the majority of DCIS have low risk of recurrence, a subset of women with germline pathogenic variants (PV) in cancer predisposition genes are at i
Externí odkaz:
https://doaj.org/article/73e4f0a88f714c8889133c651f1a54e4
Autor:
Aloran Mazumder, Athena Jimenez, Rachel E. Ellsworth, Stephen J. Freedland, Sophia George, Matthew N. Bainbridge, Svasti Haricharan
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Estrogen receptor positive (ER+) breast cancer is one of the most commonly diagnosed malignancies in women irrespective of their race or ethnicity. While Black women with ER+ breast cancer are 42% more likely to die of their disease than
Externí odkaz:
https://doaj.org/article/828661038c0b4fb98a838449cb6e2175
Autor:
Darrell L. Ellsworth, Heather L. Blackburn, Craig D. Shriver, Shahrooz Rabizadeh, Patrick Soon-Shiong, Rachel E. Ellsworth
Publikováno v:
Clinical and Translational Medicine, Vol 6, Iss 1, Pp 1-19 (2017)
Abstract Extensive genomic and transcriptomic heterogeneity in human cancer often negatively impacts treatment efficacy and survival, thus posing a significant ongoing challenge for modern treatment regimens. State-of-the-art DNA- and RNA-sequencing
Externí odkaz:
https://doaj.org/article/fecc57f36a404539abd61de8ed0951bc
Publikováno v:
Genes, Vol 11, Iss 12, p 1469 (2020)
In 2010, the genetic testing criteria was changed to allow women diagnosed ≤ 60 years old with triple negative breast cancer (TNBC) to undergo germline testing. In the same year, estrogen receptor (ER) positivity was defined as having ≥1% ER stai
Externí odkaz:
https://doaj.org/article/12f4e6fd3e9f42fca463a353379fc3c6
Publikováno v:
Cancers, Vol 12, Iss 1, p 234 (2020)
Currently, genetic testing is offered only to women diagnosed with breast cancer who meet a defined set of criteria and is not included as standard-of-care treatment at the time of diagnosis. Thus, a significant number of women diagnosed with breast
Externí odkaz:
https://doaj.org/article/cb09636e3d4a4099a4bd9c3dc4264c74
Autor:
Rachel E. Ellsworth, Lori A. Field, Brad Love, Jennifer L. Kane, Jeffrey A. Hooke, Craig D. Shriver
Publikováno v:
International Journal of Breast Cancer, Vol 2011 (2011)
Lymph node status remains one of the most useful prognostic indicators in breast cancer; however, current methods to assess nodal status disrupt the lymphatic system and may lead to secondary complications. Identification of molecular signatures disc
Externí odkaz:
https://doaj.org/article/28821128dbf243efa59b021c76820052
Publikováno v:
International Journal of Breast Cancer, Vol 2011 (2011)
Externí odkaz:
https://doaj.org/article/0584e1439e1d432e843e711f4042b443
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 3 (2009)
Pathological grade is a useful prognostic factor for stratifying breast cancer patients into favorable (low-grade, well-differentiated tumors) and less favorable (high-grade, poorly-differentiated tumors) outcome groups. Under the current system of t
Externí odkaz:
https://doaj.org/article/b0e161f67a0c493ca376a6cc0058ac09