Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rachel E. Carlisle"'
Autor:
Rachel E. Carlisle, Zahraa Mohammed-Ali, Chao Lu, Tamana Yousof, Victor Tat, Samera Nademi, Melissa E. MacDonald, Richard C. Austin, Jeffrey G. Dickhout
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Abstract Chronic kidney disease (CKD) is characterized by the gradual loss of renal function and is a major public health concern. Risk factors for CKD include hypertension and proteinuria, both of which are associated with endoplasmic reticulum (ER)
Externí odkaz:
https://doaj.org/article/89792d7cf89b43f380fd07d916bdc0a3
Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity
Autor:
Jae Hyun Byun, Paul F. Lebeau, Khrystyna Platko, Rachel E. Carlisle, Mahi Faiyaz, Jack Chen, Melissa E. MacDonald, Yumna Makda, Tamana Yousof, Edward G. Lynn, Jeffrey G. Dickhout, Joan C. Krepinsky, Fiona Weaver, Suleiman A. Igdoura, Nabil G. Seidah, Richard C. Austin
Publikováno v:
Kidney360. 3:1394-1410
Autor:
Richard C. Austin, Melissa E. MacDonald, Rachel E. Carlisle, Tamana Yousof, Jeffrey G. Dickhout, Victor Tat, Zahraa Mohammed-Ali, Chao Lu, Samera Nademi
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Chronic kidney disease (CKD) is characterized by the gradual loss of renal function and is a major public health concern. Risk factors for CKD include hypertension and proteinuria, both of which are associated with endoplasmic reticulum (ER) stress.
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 316:H1214-H1223
Essential hypertension is the leading cause of premature death worldwide. However, hypertension’s cause remains uncertain. endoplasmic reticulum (ER) stress has recently been associated with hypertension, but it is unclear whether ER stress causes
Autor:
Rachel E Carlisle, Elise Brimble, Kaitlyn E Werner, Gaile L Cruz, Kjetil Ask, Alistair J Ingram, Jeffrey G Dickhout
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84663 (2014)
Different forms of acute kidney injury (AKI) have been associated with endoplasmic reticulum (ER) stress; these include AKI caused by acetaminophen, antibiotics, cisplatin, and radiocontrast. Tunicamycin (TM) is a nucleoside antibiotic known to induc
Externí odkaz:
https://doaj.org/article/3af3a8ace4494e38b5f8942eb7082188
Autor:
Rachel E. Carlisle, Sarah Liu, Ming Chan Zhang, Chao Lu, Jeffrey G. Dickhout, Andy Phan, Elise Brimble, Salwa Farooqi
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260519 (2021)
PLoS ONE
PLoS ONE
Endoplasmic reticulum (ER) stress is associated with acute kidney injury (AKI) caused by various mechanisms, including antibiotics, non-steroidal anti-inflammatory drugs, cisplatin, and radiocontrast. Tunicamycin (TM) is a nucleoside antibiotic that
Publikováno v:
Biochemical and Biophysical Research Communications. 486:163-170
Newly translated proteins must undergo proper folding to ensure their function. To enter a low energy state, misfolded proteins form aggregates, which are associated with many degenerative diseases, such as Huntington's disease and chronic kidney dis
Autor:
Jasmine Chahal, Chandak Upagupta, Victoria Yum, Kjetil Ask, Elise Brimble, Rachel E. Carlisle, Chao Lu, Jeffrey G. Dickhout
Publikováno v:
American Journal of Physiology-Renal Physiology. 312:F230-F244
Proteinuria is one of the primary risk factors for the progression of chronic kidney disease (CKD) and has been implicated in the induction of endoplasmic reticulum (ER) stress. We hypothesized that the suppression of ER stress with a low molecular w
Autor:
Chao Lu, Victoria Yum, Jeffrey G. Dickhout, Muzammil Memon, Rachel E. Carlisle, Yejin No, Kjetil Ask, Kaitlyn E. Werner, Victor Tat
Publikováno v:
Journal of Hypertension. 34:1556-1569
Objective Our purpose was to determine if endoplasmic reticulum stress inhibition lowers blood pressure (BP) in hypertension by correcting vascular dysfunction. Methods The spontaneously hypertensive rat (SHR) was used as a model of human essential h
Publikováno v:
The FASEB Journal. 32