Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Rachel E Victor"'
1
Akademický článek
TLR4 Asp299Gly and Thr399Ile polymorphisms: no impact on human immune responsiveness to LPS or respiratory syncytial virus.
Autor: Renée N Douville, Yuriy Lissitsyn, Aaron F Hirschfeld, Allan B Becker, Anita L Kozyrskyj, Joel Liem, Nathalie Bastien, Yan Li, Rachel E Victor, Mehtab Sekhon, Stuart E Turvey, Kent T HayGlass
Publikováno v: PLoS ONE, Vol 5, Iss 8, p e12087 (2010)
A broad variety of natural environmental stimuli, genotypic influences and timing all contribute to expression of protective versus maladaptive immune responses and the resulting clinical outcomes in humans. The role of commonly co-segregating Toll-l
Externí odkaz: https://doaj.org/article/6bc7b93ae6604761a06750567f8dc153
Zobrazit plný text záznamu
3
Common human Toll-like receptor 4 polymorphisms—Role in susceptibility to respiratory syncytial virus infection and functional immunological relevance
Autor: Aaron F. Hirschfeld, Stéphane Paulus, Stuart E. Turvey, Rachel E. Victor, John Brunstein, Eva Thomas
Publikováno v: Clinical Immunology. 123:252-257
Evidence suggests that Toll-like receptor 4 (TLR4) contributes to immune recognition of respiratory syncytial virus (RSV). The TLR4 gene harbours a polymorphism-Asp299Gly-previously associated with reduced TLR4 signalling. To understand of how host g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e83c949fcebacd8c54d5dba0e66b4f
https://doi.org/10.1016/j.clim.2007.03.003
Zobrazit plný text záznamu
4
Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis
Autor: Raamesh Deshpande, Nicole J. de Voogd, Stuart E. Turvey, Sheena C. Li, Charles Boone, Shan-Yu Fung, Chad L. Myers, Raymond J. Andersen, Vladimir Sofiyev, Julia Schneiderman, Aaron F. Hirschfeld, Jeff S. Piotrowski, Rachel E. Victor, Katherine Woods
Publikováno v: ACS chemical biology. 9(1)
Toll-like receptors (TLRs) play a critical role in innate immunity, but activation of TLR signaling pathways is also associated with many harmful inflammatory diseases. Identification of novel anti-inflammatory molecules targeting TLR signaling pathw
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a63e4fc16ae74712dc0975b55a3199
https://pubmed.ncbi.nlm.nih.gov/24117378
Zobrazit plný text záznamu
5
Acidification-dependent activation of CD1d-restricted natural killer T cells is intact in cystic fibrosis
Autor: Sarah E, Rzemieniak, Aaron F, Hirschfeld, Rachel E, Victor, Mark A, Chilvers, Dongjun, Zheng, Peter, van den Elzen, Stuart E, Turvey
Publikováno v: Immunology. 130(2)
CD1d-restricted natural killer T (NKT) cells are emerging as critical regulators of the immune response to infectious agents, including Pseudomonas aeruginosa; and therapies to augment NKT-cell activation may represent a novel approach to treat chron
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3198151559d7284b069b61f64afd9838
https://pubmed.ncbi.nlm.nih.gov/20102408
Zobrazit plný text záznamu
6
Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease
Autor: Rachel E. Victor, Isaac M. Elias, Kelly D. Smith, Christoph J. Blohmke, Pearce G. Wilcox, Robert E. W. Hancock, Cheryl R. Lane, Aaron F. Hirschfeld, David G. Hancock, Joerg Overhage, Stuart E. Turvey, A. George F. Davidson
Publikováno v: Scopus-Elsevier
Novel therapies to target lung inflammation are predicted to improve the lives of people with cystic fibrosis (CF) but specific antiinflammatory targets have not been identified. The goal of this study was to establish whether TLR5 signaling is the k
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a928a3d7f8b41f0684ca7a10fa9963
http://ora.ox.ac.uk/objects/uuid:b52c9dff-075d-4fe3-aeba-a69ade0bb8be
Zobrazit plný text záznamu
7
Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection
Autor: J. Mark Ansermino, Aaron F. Hirschfeld, Julie A. Bettinger, Stuart E. Turvey, Andrew J. Currie, Jordan S. Orange, Donald J. Davidson, David W. Scheifele, Rachel E. Victor
Publikováno v: Clinical immunology (Orlando, Fla.). 122(3)
Human primary immunodeficiencies affecting Toll-like receptor (TLR) signalling reveal a non-redundant role for TLR function in defense against pneumococcal infection. To determine the clinical relevance of TLR abnormalities, we studied a population p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48570b2fa415402624d2f9b39a1a5812
https://pubmed.ncbi.nlm.nih.gov/17157070
Zobrazit plný text záznamu
9
TLR4 Asp299Gly and Thr399Ile Polymorphisms: No Impact on Human Immune Responsiveness to LPS or Respiratory Syncytial Virus
Autor: Kent T. HayGlass, Yuriy Lissitsyn, Anita L. Kozyrskyj, Stuart E. Turvey, Yan Li, Allan B. Becker, Mehtab Sekhon, J.J. Liem, Renée N. Douville, Aaron F. Hirschfeld, Nathalie Bastien, Rachel E. Victor
Publikováno v: PLoS ONE, Vol 5, Iss 8, p e12087 (2010)
PLoS ONE
Background A broad variety of natural environmental stimuli, genotypic influences and timing all contribute to expression of protective versus maladaptive immune responses and the resulting clinical outcomes in humans. The role of commonly co-segrega
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e80c38b0b27a2dcace0144434b3d1d
https://doi.org/10.1371/journal.pone.0012087
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje