Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rachel E, Lackie"'
Autor:
Rachel E. Lackie, Jose Marques-Lopes, Valeriy G. Ostapchenko, Sarah Good, Wing-Yiu Choy, Patricija van Oosten-Hawle, Stephen H. Pasternak, Vania F. Prado, Marco A. M. Prado
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract Molecular chaperones and co-chaperones, which are part of the protein quality control machinery, have been shown to regulate distinct aspects of Alzheimer’s Disease (AD) pathology in multiple ways. Notably, the co-chaperone STI1, which pre
Externí odkaz:
https://doaj.org/article/9ee481f80095427e8c20de5968f11484
Autor:
Rachel E. Lackie, Andrzej Maciejewski, Valeriy G. Ostapchenko, Jose Marques-Lopes, Wing-Yiu Choy, Martin L. Duennwald, Vania F. Prado, Marco A. M. Prado
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
The accumulation of misfolded proteins in the human brain is one of the critical features of many neurodegenerative diseases, including Alzheimer's disease (AD). Assembles of beta-amyloid (Aβ) peptide—either soluble (oligomers) or insoluble (plaqu
Externí odkaz:
https://doaj.org/article/f10efba2407246aaabc056b22a623b95
Autor:
Amanda Maple, Rachel E. Lackie, Diana I. Elizalde, Stephanie L. Grella, Chelsey C. Damphousse, Collin Xa, Amelia L. Gallitano, Diano F. Marrone
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
The dentate gyrus (DG) engages in sustained Arc transcription for at least 8 hours following behavioral induction, and this time course may be functionally coupled to the unique role of the DG in hippocampus-dependent learning and memory. The factors
Externí odkaz:
https://doaj.org/article/8c03f287fe774753867363a4a675e922
Autor:
Rachel E. Lackie, Aline S. de Miranda, Mei Peng Lim, Vladislav Novikov, Nimrod Madrer, Nadun C. Karunatilleke, Benjamin S. Rutledge, Stephanie Tullo, Anne Brickenden, Matthew E. R. Maitland, David Greenberg, Daniel Gallino, Wen Luo, Anoosha Attaran, Irina Shlaifer, Esther Del Cid Pellitero, Caroline Schild-Poulter, Thomas M. Durcan, Edward A. Fon, Martin Duennwald, Flavio H. Beraldo, M. Mallar Chakravarty, Timothy J. Bussey, Lisa M. Saksida, Hermona Soreq, Wing-Yiu Choy, Vania F. Prado, Marco A. M. Prado
Publikováno v:
Neuroscience Institute Publications
The predominantly pre-synaptic intrinsically disordered protein α-synuclein is prone to misfolding and aggregation in synucleinopathies, such as Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB). Molecular chaperones play important role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6c8d325062fc051dc64081d7b95377
https://pubmed.ncbi.nlm.nih.gov/36121476
https://pubmed.ncbi.nlm.nih.gov/36121476
Publikováno v:
Behavioural pharmacology. 32(7)
Contextual information is represented in the hippocampus (HPC) partially through the recruitment of distinct neuronal ensembles. It is believed that reactivation of these ensembles underlies memory retrieval processes. Recently, we showed that norepi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5dacad718b5b567e770dc585de6a090
https://pubmed.ncbi.nlm.nih.gov/34417358
https://pubmed.ncbi.nlm.nih.gov/34417358
Autor:
Wing-Yiu Choy, Jose Marques-Lopes, Marco A. M. Prado, Stephen H. Pasternak, Vania F. Prado, Rachel E. Lackie, Sarah C. Good, Patricija van Oosten-Hawle, Valeriy G. Ostapchenko
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Molecular chaperones and co-chaperones, which are part of the protein quality control machinery, have been shown to regulate distinct aspects of Alzheimer’s Disease (AD) pathology in multiple ways. Notably, the co-chaperone STI1, which presents inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152fe61ee52f6323c90243b8c843d94b
http://europepmc.org/articles/PMC7441634
http://europepmc.org/articles/PMC7441634
Contextual information is represented in the hippocampus (HPC) partially through the recruitment of distinct neuronal ensembles. It is believed that reactivation of these ensembles underlies memory retrieval processes. Recently, we showed that norepi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f63285c1ddc0701633c7b802829dbc8a
https://doi.org/10.1101/2020.06.07.138859
https://doi.org/10.1101/2020.06.07.138859
Autor:
Rachel E. Lackie, Gilli Moshitzky, Vania F. Prado, Wing-Yiu Choy, Martin L. Duennwald, Flavio H. Beraldo, Marilene H. Lopes, Andrzej Maciejewski, Abdul Razzaq, Jue Fan, Robert Gros, David S. Greenberg, Jason P. Lerch, Hermona Soreq, Vilma R. Martins, Marco A. M. Prado, Lily R. Qiu, Sali M.K. Farhan
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Chaperone networks are dysregulated with aging, but whether compromised Hsp70/Hsp90 chaperone function disturbs neuronal resilience is unknown. Stress-inducible phosphoprotein 1 (STI1; STIP1; HOP) is a co-chaperone that simultaneously interacts with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0a54b672a03bee85e76e92360bef80
Autor:
Hermona Soreq, Flavio H. Beraldo, Abdul Razzaq, Marco A. M. Prado, Andrzej Maciejewski, Robert Gros, Marilene H. Lopes, Jue Fan, David S. Greenberg, Wing-Yiu Choy, Sali M.K. Farhan, Gilli Moshitzky, Vania F. Prado, Vilma R. Martins, Rachel E. Lackie, Martin L. Duennwald
Chaperone networks are dysregulated with aging and neurodegenerative disease, but whether compromised Hsp70/Hsp90 chaperone function directly contributes to neuronal degeneration is unknown. Stress-inducible phosphoprotein-1 (STI1; STIP1; HOP) is a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8aa4a54a96cbe69de377e902112c80
https://doi.org/10.1101/258673
https://doi.org/10.1101/258673
Autor:
Amanda, Maple, Rachel E, Lackie, Diana I, Elizalde, Stephanie L, Grella, Chelsey C, Damphousse, Collin, Xa, Amelia L, Gallitano, Diano F, Marrone
Publikováno v:
Neural Plasticity
The dentate gyrus (DG) engages in sustained Arc transcription for at least 8 hours following behavioral induction, and this time course may be functionally coupled to the unique role of the DG in hippocampus-dependent learning and memory. The factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d68f1fa92d67075c3ac2e66dfd75ac4
https://pubmed.ncbi.nlm.nih.gov/28589041
https://pubmed.ncbi.nlm.nih.gov/28589041