Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rachel E, Jarrard"'
Autor:
Natalie R, Sealover, Bruce, Felts, Charles P, Kuntz, Rachel E, Jarrard, Gregory H, Hockerman, Patrick W, Lamb, Eric L, Barker, L Keith, Henry
Publikováno v:
Biochemical Pharmacology. 120:46-55
The substituted amphetamine, 3,4-methylenedioxy-methamphetamine (MDMA, ecstasy), is a widely used drug of abuse that induces non-exocytotic release of serotonin, dopamine, and norepinephrine through their cognate transporters as well as blocking the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f05a06d1aed6c5050d8d4bd361066a
https://doi.org/10.1016/j.bcp.2016.09.006
https://doi.org/10.1016/j.bcp.2016.09.006
Autor:
Marcy L. Guerra, Ian M. Soderling, Gregory H. Hockerman, Allison M. Lange, Yuchen Wang, Amy E. Salyer, Hilary J. Broderick, Evan P.S. Pratt, Rachel E. Jarrard
Publikováno v:
Molecular Pharmacology. 83:191-205
Tolbutamide and gliclazide block the K(ATP) channel K(ir)6.2/Sur1, causing membrane depolarization and stimulating insulin secretion in pancreatic beta cells. We examined the ability of the EPAC-selective cAMP analog 8-pCPT-2'-O-Me-cAMP-AM to potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576501f9fb161c362ab24e4e70cfecbb
https://doi.org/10.1124/mol.112.081943
https://doi.org/10.1124/mol.112.081943
Autor:
Patrick W Lamb, Charles P. Kuntz, Rachel E. Jarrard, Eric L. Barker, Gregory H. Hockerman, Natalie Sealover, L. Keith Henry, Bruce Felts
Publikováno v:
Biochemical Pharmacology. 147:9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e523ad48530d656f3adbc6e5e72ada
https://doi.org/10.1016/j.bcp.2017.11.001
https://doi.org/10.1016/j.bcp.2017.11.001
Autor:
Rachel E. Jarrard, Allison M. Lange, Amy E. Salyer, Evan P.S. Pratt, Gregory H. Hockerman, Ian M. Soderling, Yuchen Wang, Marcy L. Guerra
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 28(4)
We investigated the role of Cav1.2 in pancreatic β-cell function by expressing a Cav1.2 II-III loop/green fluorescent protein fusion in INS-1 cells (Cav1.2/II-III cells) to disrupt channel-protein interactions. Neither block of KATP channels nor sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c67de4cc71520b226d60cbf1988b44e
https://pubmed.ncbi.nlm.nih.gov/24506535
https://pubmed.ncbi.nlm.nih.gov/24506535
Autor:
Gregory H. Hockerman, Tolani K. Salvador, Matthew S. Powers, David A. Colby, Rachel E. Jarrard, Julia A. Chester, Changho Han, Eun Hoo Kim, Amy E. Salyer, Xinyi Jiang, Aaron M. Kirchhoff
Publikováno v:
Journal of medicinal chemistry. 56(6)
The design, synthesis, biological evaluation, and in vivo studies of difluoromethyl ketones as GABAB agonists that are not structurally analogous to known GABAB agonists, such as baclofen or 3-aminopropyl phosphinic acid, are presented. The difluorom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4256e178a61e58c5c77098c19d20404e
https://pubmed.ncbi.nlm.nih.gov/23428109
https://pubmed.ncbi.nlm.nih.gov/23428109
Autor:
Julie A. Przybyla, Guohong Liu, Marcy L. Guerra, Val J. Watts, Gregory H. Hockerman, Rachel E. Jarrard, Sarah Melissa P. Jacobo
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 330(1)
L-type Ca(2+) channels play a key role in the integration of physiological signals regulating insulin secretion that probably requires their localization to specific subdomains of the plasma membrane. We investigated the role of the intracellular II-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c57af1d3d9f77fc535d3aee6e9f5686
https://pubmed.ncbi.nlm.nih.gov/19351867
https://pubmed.ncbi.nlm.nih.gov/19351867