Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rachel Deplus"'
Autor:
Gaurav Dube, Assia Tiamiou, Martin Bizet, Yasmine Boumahd, Imène Gasmi, Rebekah Crake, Justine Bellier, Marie-Julie Nokin, Emilie Calonne, Rachel Deplus, Tom Wissocq, Olivier Peulen, Vincent Castronovo, François Fuks, Akeila Bellahcène
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Aerobic glycolysis, also known as the Warburg effect, is predominantly upregulated in a variety of solid tumors, including breast cancer. We have previously reported that methylglyoxal (MG), a very reactive by-product of glycolysi
Externí odkaz:
https://doaj.org/article/99203b58e323473ab885bd1de0fe091d
Autor:
Maud De Dieuleveult, Martin Bizet, Laurence Colin, Emilie Calonne, Martin Bachman, Chao Li, Irina Stancheva, Benoit Miotto, François Fuks, Rachel Deplus
Publikováno v:
Epigenetics, Vol 17, Iss 4, Pp 422-443 (2022)
Ten-Eleven Translocation (TET) proteins convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) leading to a dynamic epigenetic state of DNA that can influence transcription and chromatin organization. While TET proteins interact with comple
Externí odkaz:
https://doaj.org/article/5adf755568894664aea40507c9488355
Autor:
Jie Lan, Nicholas Rajan, Martin Bizet, Audrey Penning, Nitesh K. Singh, Diana Guallar, Emilie Calonne, Andrea Li Greci, Elise Bonvin, Rachel Deplus, Phillip J. Hsu, Sigrid Nachtergaele, Chengjie Ma, Renhua Song, Alejandro Fuentes-Iglesias, Bouchra Hassabi, Pascale Putmans, Frédérique Mies, Gerben Menschaert, Justin J. L. Wong, Jianlong Wang, Miguel Fidalgo, Bifeng Yuan, François Fuks
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
TET mediated RNA-hydroxymethylation (5hmC) has been detected in mammals, but its physiological role remains unclear. Here the authors map 5hmC during embryonic stem cell (ESC) differentiation and find that Tet-mediated RNA hydroxymethylation reduces
Externí odkaz:
https://doaj.org/article/9305faa1ca904cdba667b6f5f1a6c75f
Autor:
Rachel Deplus, Loïc Blanchon, Arumugam Rajavelu, Abdelhalim Boukaba, Matthieu Defrance, Judith Luciani, Françoise Rothé, Sarah Dedeurwaerder, Hélène Denis, Arie B. Brinkman, Femke Simmer, Fabian Müller, Benjamin Bertin, Maria Berdasco, Pascale Putmans, Emilie Calonne, David W. Litchfield, Yvan de Launoit, Tomasz P. Jurkowski, Hendrik G. Stunnenberg, Christoph Bock, Christos Sotiriou, Mario F. Fraga, Manel Esteller, Albert Jeltsch, François Fuks
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 743-753 (2014)
DNA methylation is a central epigenetic modification that is established by de novo DNA methyltransferases. The mechanisms underlying the generation of genomic methylation patterns are still poorly understood. Using mass spectrometry and a phosphospe
Externí odkaz:
https://doaj.org/article/a2e48f8c7f1944aaba57f0d1231bcd9a
Autor:
Samuel Guenin, Mustapha Mouallif, Rachel Deplus, Xavier Lampe, Nathalie Krusy, Emilie Calonne, Katty Delbecque, Frederic Kridelka, François Fuks, My Mustapha Ennaji, Philippe Delvenne
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42704 (2012)
Promoter methylation profiles are proposed as potential prognosis and/or diagnosis biomarkers in cervical cancer. Up to now, little is known about the promoter methylation profile and expression pattern of stem cell (SC) markers during tumor developm
Externí odkaz:
https://doaj.org/article/4d38725939264037b81b3a189d99caf5
Autor:
Lionel Malbec, Margot Celerier, Martin Bizet, Emilie Calonne, Heike Hofmann-Winkler, Bram Boeckx, Rana Abdelnabi, Pascale Putmans, Bouchra Hassabi, Lieve Naesens, Diether Lambrechts, Stefan Pöhlmann, Rachel Deplus, Leen Delang, Jana Jeschke, François Fuks
The RNA modification N6-methyladenosine (m6A) plays a key role in the life cycles of several RNA viruses. Whether this applies to SARS-CoV-2 and whether m6A affects the outcome of COVID-19 disease is still poorly explored. Here we report that the RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30ac1819995083ca0797ad79e1ab54c1
https://doi.org/10.1101/2022.06.27.497749
https://doi.org/10.1101/2022.06.27.497749
Autor:
Cheng-Jie Ma, Sigrid Nachtergaele, Nitesh Kumar Singh, Nicholas Rajan, Gerben Menschaert, Miguel Fidalgo, Martin Bizet, Jianlong Wang, Bouchra Hassabi, Andrea Li Greci, Elise Bonvin, François Fuks, Pascale Putmans, Emilie Calonne, Bi-Feng Yuan, Diana Guallar, Alejandro Fuentes-Iglesias, Phillip J. Hsu, Renhua Song, Rachel Deplus, Audrey Penning, Justin J.-L. Wong, Jie Lan, Frédérique Mies
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
NATURE COMMUNICATIONS
Nature Communications
Nature communications, 11 (1
NATURE COMMUNICATIONS
Nature Communications
Nature communications, 11 (1
Tet-enzyme-mediated 5-hydroxymethylation of cytosines in DNA plays a crucial role in mouse embryonic stem cells (ESCs). In RNA also, 5-hydroxymethylcytosine (5hmC) has recently been evidenced, but its physiological roles are still largely unknown. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d865b84307caaf1748bb636ada22b193
https://doaj.org/article/9305faa1ca904cdba667b6f5f1a6c75f
https://doaj.org/article/9305faa1ca904cdba667b6f5f1a6c75f
Autor:
Rachel Deplus, François Fuks, Martin Bizet, Martin Bachman, Chao Li, Benoit Miotto, Laurence Colin, Irina Stancheva, Maud de Dieuleveult, Emilie Calonne
Publikováno v:
Epigenetics
Epigenetics, Taylor & Francis, 2021, Online ahead of print. ⟨10.1080/15592294.2021.1917152⟩
Epigenetics, 2021, Online ahead of print. ⟨10.1080/15592294.2021.1917152⟩
Epigenetics, Taylor & Francis, 2021, Online ahead of print. ⟨10.1080/15592294.2021.1917152⟩
Epigenetics, 2021, Online ahead of print. ⟨10.1080/15592294.2021.1917152⟩
International audience; Ten-Eleven Translocation (TET) proteins convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) leading to a dynamic epigenetic state of DNA that can influence transcription and chromatin organization. While TET prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b969e156554f9460fd291d41c72421f
https://www.hal.inserm.fr/inserm-03357207/document
https://www.hal.inserm.fr/inserm-03357207/document
Autor:
Eleonora Leucci, Emilie Calonne, Rachel Deplus, Ghanem Elias Ghanem, Robert L. Ross, Soizic Garaud, Luis Augusto Teixeira, Clémence Al Wardi, Yacine Bareche, Jacqueline Lehmann-Che, Martine Duterque-Coquillaud, Zena Wimana, Alexander Koch, Kateryna Shostak, Xavier Leroy, Martin Bizet, Renato Morandini, Alain Chariot, Mingzhou Guo, Evelyne Collignon, Mohammad Krayem, Pascale Putmans, Pierre Close, Yan Jia, Gaurav Dube, Karen Willard-Gallo, Jean-Christophe Marine, François Fuks, Jana Jeschke, Françoise Rothé, Christos Sotiriou, Bi-Feng Yuan, Lara Rizzotto, Gerben Menschaert, Nitesh Kumar Singh, Christine Desmedt, Patrick A. Limbach, Bouchra Hassabi
Publikováno v:
Nature Cancer, 2(6), 611-+. Nature Publishing Group
Nature Cancer, 2 (6
Nature Cancer, 2 (6
Post-transcriptional modifications of RNA constitute an emerging regulatory layer of gene expression. The demethylase fat mass- and obesity-associated protein (FTO), an eraser of N-6-methyladenosine (m(6)A), has been shown to play a role in cancer, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664ad06e0e6411b736f6c75e2983edd7
https://cris.maastrichtuniversity.nl/en/publications/390eaf3a-0be7-4885-9c94-0bc066fd2220
https://cris.maastrichtuniversity.nl/en/publications/390eaf3a-0be7-4885-9c94-0bc066fd2220
Autor:
Rachel Deplus, Martine Duterque-Coquillaud, Anne Flourens, Edith Bonnelye, Nathalie Vanpouille, Tian V. Tian, Philippe Clézardin, Anais Fradet, Carine Delliaux, Xavier Leroy, Yvan de Launoit, Mathilde Bouchet, Arnauld Villers
Publikováno v:
Cancer Letters
Cancer Letters, Elsevier, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, Elsevier, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
International audience; Abstract : Prostate cancers have a strong propensity to metastasize to bone and promote osteoblastic lesions. TMPRSS2:ERG is the most frequent gene rearrangement identified in prostate cancer, but whether it is involved in pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2efdc0696479c6db9b921256206c223
https://doi.org/10.1016/j.canlet.2018.08.027
https://doi.org/10.1016/j.canlet.2018.08.027