Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rachel Delston"'
Autor:
Robyn Puro, Ronald Hiebsch, Michael Donio, Benjamin Capoccia, Arun Kashyap, Daniel Pereira, Gabriela Andrejeva, Rachel Delston, Casey Wilson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/5ea9add8ab9d4c4297ee134cebe5d2b2
Autor:
Ronald R. Hiebsch, Robyn J Puro, Casey Wilson, Rachel Delston, Daniel S. Pereira, Arun K. Kashyap, Benjamin J. Capoccia, Michael J. Donio, Gabriela Andrejeva
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundCD47 is a cell surface protein expressed on tumors that binds SIRPα on macrophages and dendritic cells resulting in a ”don’t eat me” signal that allows tumors to evade phagocytosis. The highly differentiated monoclonal antibody, AO-1
Autor:
John J. Correia, Kai Lin, Rachel Delston, Hema Srinath, Suvana S. Lam, Bin Y. Qin, Rik Derynck, Cheng Liu
Publikováno v:
Nature Structural & Molecular Biology. 10:913-921
IRF-3, a member of the interferon regulatory factor (IRF) family of transcription factors, functions as a molecular switch for antiviral activity. IRF-3 uses an autoinhibitory mechanism to suppress its transactivation potential in uninfected cells, a
Publikováno v:
The EMBO journal. 24(14)
Transforming growth factor-beta (TGF-beta) inhibits osteoblast differentiation through inhibition of the function of Runx2 (Cbfa1) by Smad3. The mechanism through which TGF-beta/Smad3 inhibits Runx2 function has not been characterized. We show that T