Výsledky vyhledávání - "Rachel D Moloney"

Akademický článek

Conditional deletion of glucocorticoid receptors in rat brain results in sex-specific deficits in fear and coping behaviors

Autor: Jessie R Scheimann, Rachel D Moloney, Parinaz Mahbod, Rachel L Morano, Maureen Fitzgerald, Olivia Hoskins, Benjamin A Packard, Evelin M Cotella, Yueh-Chiang Hu, James P Herman

Publikováno v: eLife, Vol 8 (2019)

Glucocorticoid receptors (GR) have diverse functions relevant to maintenance of homeostasis and adaptation to environmental challenges. Understanding the importance of tissue-specific GR function in physiology and behavior has been hampered by near-u

Externí odkaz: https://doaj.org/article/f9a00f4e02414ddb96a45b0f09742316

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Akademický článek

Stress-Induced Visceral Pain: Towards Animal Models of Irritable-Bowel Syndrome and Associated Co-morbidities

Autor: Rachel D Moloney, Siobhain Mary O' Mahony, Timothy G Dinan, John F Cryan

Publikováno v: Frontiers in Psychiatry, Vol 6 (2015)

Visceral pain is a global term used to describe pain originating from the internal organs, which is distinct from somatic pain. It is a hallmark of functional gastrointestinal disorders such as irritable bowel syndrome (IBS). Currently the treatment

Externí odkaz: https://doaj.org/article/a7bbf0e7fd9d42a387d28c21f53e4178

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Akademický článek

Adolescent Stress Confers Resilience to Traumatic Stress Later in Life: Role of the Prefrontal Cortex

Autor: Evelin M. Cotella, Nawshaba Nawreen, Rachel D. Moloney, Susan E. Martelle, Kristen M. Oshima, Paige Lemen, Jordan N. NiBlack, Reetu R. Julakanti, Maureen Fitzgerald, Mark L. Baccei, James P. Herman

Publikováno v: Biological Psychiatry Global Open Science, Vol 3, Iss 2, Pp 274-282 (2023)

Background: Adolescent brains are sensitive to stressors. However, under certain circumstances, developmental stress can promote an adaptive phenotype, allowing individuals to cope better with adverse situations in adulthood, thereby contributing to

Externí odkaz: https://doaj.org/article/2422ee7d70db44889b11eef3005f0efa

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Molecular Neurobiology of Loss

Autor: Marissa A. Smail, Brittany L. Smith, Rammohan Shukla, Khaled Alganem, Hunter M. Eby, Justin L. Bollinger, Ria K. Parikh, James B. Chambers, James K. Reigle, Rachel D. Moloney, Nawshaba Nawreen, Eric S. Wohleb, Harry Pantazopoulos, Robert E. McCullumsmith, James P. Herman

Psychological loss is a common experience that erodes well-being and negatively impacts quality of life. The molecular underpinnings of loss are poorly understood. Here, we investigate the mechanisms of loss using an enrichment removal (ER) paradigm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::327ab4b0135ff2a885e425a5ca0bae5c
https://doi.org/10.1101/2022.07.13.499899

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Gut microbiota alterations promote traumatic stress susceptibility associated with p-cresol-induced dopaminergic dysfunctions

Autor: Samuele Laudani, Sebastiano A. Torrisi, Silvia Alboni, Thomaz F.S. Bastiaanssen, Cristina Benatti, Veronica Rivi, Rachel D. Moloney, Virginia Fuochi, Pio M. Furneri, Filippo Drago, Salvatore Salomone, Fabio Tascedda, John F. Cryan, Gian Marco Leggio

Publikováno v: Brain, behavior, and immunity. 107

Mounting evidence suggests a link between gut microbiota abnormalities and post-traumatic stress disorder (PTSD). However, whether and how the gut microbiota influences PTSD susceptibility is poorly understood. Here using the arousal-based individual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f985af455ab79fe05950628e8259b92
https://pubmed.ncbi.nlm.nih.gov/36400332

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Enduring Behavioral Effects Induced by Birth by Caesarean Section in the Mouse

Publikováno v: Current Biology, 30(19), 3761-3774. CELL PRESS
Current Biology, 30(19), 3761-3774.e6
Current Biology 30 (2020) 19

Birth by Caesarean (C)-section impacts early gut microbiota colonization and is associated with an increased risk of developing immune and metabolic disorders. Moreover, alterations of the microbiome have been shown to affect neurodevelopmental traje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3f7acb609b10976ac67ca9dacf9f8d
https://research.rug.nl/en/publications/89ae24da-1318-4766-9522-0f12bf802ffd

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Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice

Autor: John F. Cryan, Timothy G. Dinan, Catherine Stanton, Aurelijus Burokas, Kiera Murphy, Rachel D. Moloney, Gerard Clarke, Silvia Arboleya, Veronica L. Peterson

Publikováno v: Biological Psychiatry. 82:472-487

Background The realization that the microbiota-gut-brain axis plays a critical role in health and disease, including neuropsychiatric disorders, is rapidly advancing. Nurturing a beneficial gut microbiome with prebiotics, such as fructo-oligosacchari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff71b67dea7fecf7cfb9169bad731756
https://doi.org/10.1016/j.biopsych.2016.12.031

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Microbial regulation of microRNA expression in the amygdala and prefrontal cortex

Autor: Gerard Clarke, Alan E. Hoban, Timothy G. Dinan, Gerard M. Moloney, Rachel D. Moloney, Roman M. Stilling, John F. Cryan, Fergus Shanahan

Publikováno v: Microbiome, Vol 5, Iss 1, Pp 1-11 (2017)
Microbiome

Background There is growing evidence for a role of the gut microbiome in shaping behaviour relevant to many psychiatric and neurological disorders. Preclinical studies using germ-free (GF) animals have been essential in contributing to our current un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d38e1ee3bac2419ce49bd929369189
http://link.springer.com/article/10.1186/s40168-017-0321-3

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