Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rachel Chamias"'
Autor:
Meital Shukrun, Azhar Jabareen, Ammar Abou-Kandil, Rachel Chamias, Mordechai Aboud, Mahmoud Huleihel
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89390 (2014)
BRCA1 is a multifunctional tumor suppressor, whose expression is activated by the estrogen (E2)-liganded ERα receptor and regulated by certain recruited transcriptional co-activators. Interference with BRCA1 expression and/or functions leads to high
Externí odkaz:
https://doaj.org/article/e6f75c93007349e0a7c19d4b5562ea37
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29934 (2012)
We have previously shown that TPA activates HTLV-1 LTR in Jurkat T-cells by inducing the binding of Sp1-p53 complex to the Sp1 site residing within the Ets responsive region 1 (ERR-1) of the LTR and that this activation is inhibited by PKCalpha and P
Externí odkaz:
https://doaj.org/article/7407d222ffdb451b82c5c6a30091512a
Publikováno v:
Cell Cycle. 10:3337-3345
Adult T-cell leukemia (ATL) is caused by HTLV-I. The viral Tax oncoprotein plays a central role in initiating the process to ATL. However, after infection HTLV-1 enters into latency, during which virus gene expression is very low, so that the level o
Autor:
Lilach Gohari, Min Li-Weber, Mahmoud Huleihel, Mordechai Aboud, Inbal Azran-Shaish, Yana Schavinsky-Khrapunsky, Yulia Tabakin-Fix, Rachel Chamias
Publikováno v:
Current Cancer Therapy Reviews. 2:101-113
Publikováno v:
Leukemia research. 34(1)
We demonstrate here that TPA activates HTLV-1 LTR expression in Jurkat and H9 T-cell lines, by strictly different mechanisms. In Jurkat cells this activation is exerted by a PKCalpha- and PKCvarepsilon-antagonized mechanism which operates through an
Autor:
Rachel Chamias, Ammar Abou-Kandil, Mordechai Aboud, Mahmoud Huleihel, Meital Shukrun, Azhar Jabareen
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89390 (2014)
PLoS ONE
PLoS ONE
BRCA1 is a multifunctional tumor suppressor, whose expression is activated by the estrogen (E2)-liganded ERα receptor and regulated by certain recruited transcriptional co-activators. Interference with BRCA1 expression and/or functions leads to high
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 1, p e29934 (2012)
PLoS ONE, Vol 7, Iss 1, p e29934 (2012)
We have previously shown that TPA activates HTLV-1 LTR in Jurkat T-cells by inducing the binding of Sp1-p53 complex to the Sp1 site residing within the Ets responsive region 1 (ERR-1) of the LTR and that this activation is inhibited by PKCalpha and P