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of 5
pro vyhledávání: '"Rachel Catterall"'
Autor:
Cornélia Biehler, Li-Ting Wang, Myriam Sévigny, Alexandra Jetté, Clémence L Gamblin, Rachel Catterall, Elise Houssin, Luke McCaffrey, Patrick Laprise
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008674 (2020)
Epithelial cell polarity defects support cancer progression. It is thus crucial to decipher the functional interactions within the polarity protein network. Here we show that Drosophila Girdin and its human ortholog (GIRDIN) sustain the function of c
Externí odkaz:
https://doaj.org/article/c6d446d3491048b99a113c4d201ddbaf
Autor:
Eric Haines, Michael Burke, Rachel Catterall, Victor De Jesus, Bin Li, Joseph D. Manna, George Punkosdy, Oksana Zavidij, Sarah R. Wessel, Grace Werosta, Jill Cavanaugh, Sheila Newhouse, Aravind Basavapathruni, Lan Xu, Sergio Santillana, X. Michelle Zhang, Sabine K. Ruppel
Publikováno v:
Molecular Cancer Research. 21:PR10-PR10
Alterations in the RAS/RAF/MEK/ERK pathway are the most common drivers of oncogenesis. Although MEK is a clinically validated cancer target and several MEK inhibitors have been approved by the FDA, their clinical utility is limited to BRAFV600 mutant
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2438
Epithelial tissues are highly organized structures that are structured at both the cellular and tissue levels. Individual cells are characterized by an apical membrane facing a central lumen, and a basolateral membrane that contacts adjacent cells an
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0fbcef70340538f5e22ac64987d6ced
https://doi.org/10.1007/978-1-0716-2035-9_26
https://doi.org/10.1007/978-1-0716-2035-9_26
Publikováno v:
International Journal of Cancer. 146:1578-1591
Breast cancer remains a leading cause of cancer-related death for women. The stepwise development of breast cancer through preinvasive to invasive disease is associated with progressive disruption of cellular and tissue organization. Apical-basal pol