Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Rachel Caspi"'
Publikováno v:
Bio-Protocol, Vol 6, Iss 18 (2016)
The contribution of microbiota in regulating multiple physiological and pathological host responses has been studied intensively in recent years. Evidence suggests that commensal microbiota can directly modulate different populations of cells of the
Externí odkaz:
https://doaj.org/article/de2f764f2d6145bb99e3a519e852323b
Autor:
Pulak Nath, Mary Maclean, Vijay Nagarajan, Jung Lee, Mehmet Yakin, Aman Kumar, Hadi Nadali, Brian Schmidt, Koray Dogan Kaya, Shilpa Kodati, Alice Young, Rachel Caspi, Jonas Kuiper, Nida Sen
MHC-I-opathies are inflammatory conditions strongly associated with HLA class I genes. The striking association with HLA class I suggests involvement of T cells, whereas natural killer (NK) cell involvement remains largely unstudied. Here we show tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22450ea4bdaef9a216444866e28391e2
https://doi.org/10.21203/rs.3.rs-2272009/v1
https://doi.org/10.21203/rs.3.rs-2272009/v1
Autor:
Lingjun Zhang, Nozha Borjini, Yu Lun, Sweta Parab, Gospel Asonye, Rupesh Singh, Brent A. Bell, Vera L. Bonilha, Andrei Ivanov, David A. Fox, Rachel Caspi, Feng Lin
Publikováno v:
JCI Insight. 7
Cub domain-containing protein 1 (CDCP1) is a protein that is highly expressed on the surface of many cancer cells. However, its distribution in normal tissues and its potential roles in nontumor cells are poorly understood. We found that CDCP1 is pre
Autor:
Ryan S. Salvador, Reiko Horai, Yingyos Jittayasothorn, Jihong Tang, Colm O’Huigin, Vishal Thovarai, Wuxing Yuan, Rachel Caspi
Publikováno v:
The Journal of Immunology. 202:191.6-191.6
Autoimmune uveitis, thought to be driven by retina-specific T cells, is a major cause of blindness. Using a model of experimental autoimmune uveitis (EAU), we showed that long-term elimination of commensals by oral antibiotic treatment (ABX) did not
Publikováno v:
The Journal of Immunology. 202:191.5-191.5
Conjunctiva-associated lymphoid tissue (CALT) resembles a conventional mucosal immune tissue, and harbors a variety of immune cells. CALT is exposed to diverse microorganisms that come in contact with the ocular surface. Previously, we demonstrated t
Autor:
Wei, Liang, Zaruhi, Karabekian, Mary, Mattapallil, Qihong, Xu, Angelia M, Viley, Rachel, Caspi, David W, Scott
Publikováno v:
Clinical Immunology. 118:35-41
Uveitis is an important autoimmune disease affecting an estimated 2.3 million Americans. This disease is manifested by inflammation of the retina mediated by the infiltration of T lymphocytes that recognize “S-Antigen” (S-Ag). Current therapies i
Autor:
Rachel Caspi
Publikováno v:
Innate Immunity and the Eye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17daea930be0983075906ca00ba4cc03
https://doi.org/10.5005/jp/books/11844_17
https://doi.org/10.5005/jp/books/11844_17
Autor:
Rachel Caspi, Mary Mattapallil, Rachael Rigden, Carlos Zarate-Blades, Phyllis Silver, Dror Luger, Chi Chao Chan
Publikováno v:
The Journal of Immunology. 194:118.3-118.3
IL-22 has opposing effects in different tissues, from pro-inflammatory (skin, joints) to protective (liver, intestine) but little is known about its effects on neuronal tissue. We examined this using the induced models of experimental autoimmune uvei
Autor:
Anthony St. Leger, Rachel Caspi
Publikováno v:
The Journal of Immunology. 194:205.3-205.3
Previous studies have suggested a critical role for the functionality of conjunctiva‑associated lymphoid tissue (CALT), a mucosal immune tissue of the ocular surface, to maintain anterior ocular health. In this study, we developed a working animal
Publikováno v:
The Journal of Immunology. 194:114.21-114.21
Glaucoma is a disease that leads to degeneration of retinal ganglion cells (RGC) and is potentially blinding if left untreated. Based on the concept of “beneficial autoimmunity”, we examined whether naïve, retina-specific T lymphocytes can provi