Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rachel Cantrell"'
Autor:
Rachel Cantrell, Joseph S. Palumbo
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 4, Pp n/a-n/a (2022)
Abstract Significant data have accumulated demonstrating a reciprocal relationship between cancer and the hemostatic system whereby cancer promotes life‐threatening hemostatic system dysregulation (e.g., thromboembolism, consumptive coagulopathy),
Externí odkaz:
https://doaj.org/article/4c79a850d86a47b8a4b58c7df0ed6f90
Autor:
Melanie C. McKell, Rebecca R. Crowther, Stephanie M. Schmidt, Michelle C. Robillard, Rachel Cantrell, Maria A. Lehn, Edith M. Janssen, Joseph E. Qualls
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Macrophages are indispensable immune cells tasked at eliminating intracellular pathogens. Mycobacterium tuberculosis (Mtb), one of the most virulent intracellular bacterial pathogens known to man, infects and resides within macrophages. While macroph
Externí odkaz:
https://doaj.org/article/b6fbae7edb794379b09f502c787ed320
Autor:
Laura Agresta, Maria Lehn, Kristin Lampe, Rachel Cantrell, Cassandra Hennies, Sara Szabo, Trisha Wise-Draper, Kasper Hoebe, Edith M Janssen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundDeveloping novel strategies to overcome the immunosuppressive tumor microenvironment is a critically important area of cancer therapy research. Here, we assess the therapeutic potential of CD244 (2B4/signaling lymphocyte activation molecule
Externí odkaz:
https://doaj.org/article/399509727da14162bd5e3fe439ed4134
Autor:
Matthew J. Flick, Miki Watanabe-Chailland, Bal Krishan Sharma, Rebekah Karns, Rachel Cantrell, Duaa Mureb, Brenton J Francisco, Jacob Mast, Lindsey E. Romick-Rosendale, Joseph S. Palumbo, Patrick W. Whitlock, Leah Rosenfeldt, Sumit Murab
Publikováno v:
J Thromb Haemost
Background We previously showed that fibrinogen is a major determinant of the growth of a murine model of colorectal cancer (CRC). Objective Our aim was to define the mechanisms coupling fibrin(ogen) to CRC growth. Results CRC tumors transplanted int
Autor:
Rachel Cantrell, Leah Rosenfeldt, Bal Krishan Sharma, Benjamin Gourley, Alexey Revenko, Brett Monia, Joseph Palumbo
Publikováno v:
The Journal of Immunology. 208:121.12-121.12
CD8+ tumor infiltrating lymphocytes (TIL) are critical for tumor clearance following immune checkpoint inhibitor (ICI) therapy. Thrombin, the central hemostatic protease, is activated in the tumor microenvironment and CD8+ T cells express the thrombi
Autor:
Edith M Janssen, Sara Szabo, Rachel Cantrell, Kasper Hoebe, Laura Conforti, Maria A. Lehn, Trisha Wise-Draper, Kristin Lampe, Laura Agresta, Cassandra M. Hennies
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundDeveloping novel strategies to overcome the immunosuppressive tumor microenvironment is a critically important area of cancer therapy research. Here, we assess the therapeutic potential of CD244 (2B4/signaling lymphocyte activation molecule
Autor:
Kasper Hoebe, Edith M. Janssen, Cassandra M. Hennies, Maria A. Lehn, Rachel Cantrell, Kristin Lampe, Jared Klarquist
Publikováno v:
Immunohorizons
Myriad studies have linked type I IFN to the pathogenesis of autoimmune diseases, including systemic lupus erythematosus (SLE). Although increased levels of type I IFN are found in patients with SLE, and IFN blockade ameliorates disease in many mouse
Fibrin(ogen) Promotes Immune Cell Infiltration, Dysbiosis and ROS Production in Experimental Colitis
Autor:
Matthew J. Flick, Lindsey E. Romick-Rosendale, Benjamin E Gourley, Leah Rosenfeldt, Olivia Edwards, Miki Watanabe, Ramesh Kudira, David B. Haslam, Joseph S. Palumbo, Bal Krishan Sharma, Rachel Cantrell
Publikováno v:
Blood. 138:443-443
Elevated stool fibrinogen has recently been shown to predict disease course in ulcerative colitis (UC), suggesting that fibrin(ogen) in the colitis microenvironment promotes UC pathogenesis. This conclusion is consistent with previous studies from ou
Autor:
Joseph S. Palumbo, Rachel Cantrell
Publikováno v:
Thrombosis research. 191
The last half century of cancer research has seen an explosion in our understanding of the complex interplay between cancer cells and host-derived factors critical for cancer progression. Two important host-derived arms that are part of this complex
Autor:
B. Monia, M. Lehn, L. Rosenfeldt, E. Janssen, B.K. Sharma, Joseph S. Palumbo, A. Revenko, Rachel Cantrell, D. Mureb
Publikováno v:
Thrombosis Research. 200:S10