Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rachel Baribault Kent"'
Publikováno v:
Current Opinion in Biotechnology. 17:638-642
As potential therapeutics, peptides offer several advantages over small molecules (increased specificity) and antibodies (small size). Nevertheless, a number of key issues have hampered their use as drug candidates. A series of new technologies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2a380077a008d655e8391199fa4273
https://doi.org/10.1016/j.copbio.2006.10.002
https://doi.org/10.1016/j.copbio.2006.10.002
Autor:
Hennie R. Hoogenboom, Edward H. Cohen, Shannon Hogan, Isaac J. Rondon, Malini Viswanathan, Jennifer A. Leeds, Robert Charles Ladner, Andrew E. Nixon, Marc Daukandt, Rachel Baribault Kent, Sonia Schoonbroodt, Nicole Coolen-van Neer, Nastri Horacio G, Guannan Kuang, Daniel J. Sexton, Lili Huang, Kristin L. Rookey, Louise Rem, Irina Kashin, Rob van Hegelsom, Mieke Steukers, Simon E. Hufton, Mary Devlin, Henk Pieters, Nicolas Frans, Rene Hoet
Publikováno v:
Nature Biotechnology. 23:344-348
Combinatorial libraries of rearranged hypervariable V(H) and V(L) sequences from nonimmunized human donors contain antigen specificities, including anti-self reactivities, created by random pairing of V(H)s and V(L)s. Somatic hypermutation of immunog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ee38e2a6e16eb22f970e86cc5aa60a
https://doi.org/10.1038/nbt1067
https://doi.org/10.1038/nbt1067
Autor:
R.C. Ladner, D W White, W. Markland, Rachel Baribault Kent, Bruce L. Roberts, Sonia Kosow Guterman, A C Ley
Inhibitors of human neutrophil elastase were engineered by designing and producing a library of phage-displayed protease inhibitory domains derived from wild-type bovine pancreatic trypsin inhibitor and fractionating the library for binding to the ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39d6e268f8c2b5c607259492916adfe
https://europepmc.org/articles/PMC48671/
https://europepmc.org/articles/PMC48671/
Publikováno v:
Nature. 305(5933)
Our previous studies with the mouse myeloma MOPC 315 (IgA, lambda 2) cell line, using myeloma mutants that had deleted the productive alpha heavy (H)-chain gene, had shown that the excluded alpha constant-region (C alpha) allele in these cells is tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea34cf043b295e6ee90acf5c4284822f
https://pubmed.ncbi.nlm.nih.gov/6413865
https://pubmed.ncbi.nlm.nih.gov/6413865
Publikováno v:
Moleculargeneral genetics : MGG. 187(2)
To determine the molecular basis for the temperature-sensitivity of pure rho RNA-dependent ATPase from Escherichia coli mutant rho-115 cells, we investigated mutant rho binding to [3H] polyC as measured by retention on nitrocellulose filters. Complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f643c16d007dab30056076118f7132b4
https://pubmed.ncbi.nlm.nih.gov/6217399
https://pubmed.ncbi.nlm.nih.gov/6217399
The effects of pyrophosphate on RNA binding and ATPase activities of Escherichia coli transcription termination factor rho have been studied. Mutant rho-115 protein has a temperature-sensitive RNA-dependent ATPase activity due to the thermolability o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060320197832796e55097029e0c3e95c
https://europepmc.org/articles/PMC346562/
https://europepmc.org/articles/PMC346562/
Autor:
Michael Dean, Ann Marshak-Rothstein, James E. McCormack, Gail E. Sonenshein, Vincent H. Pepe, Rachel Baribault Kent
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 81(17)
The c-myc oncogene has been implicated in a wide spectrum of B-cell neoplasias. In normal cells, the level of expression of the c-myc gene correlates with growth status. In the present study, we examined the effect of receptor-mediated inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0bc3a87d2d27e967ceb1a1032bf1c7
https://pubmed.ncbi.nlm.nih.gov/6206500
https://pubmed.ncbi.nlm.nih.gov/6206500
Autor:
Michael Dean, Gail E. Sonenshein, Vincent H. Pepe, Ann Marshak-Rothstein, James E. McCormack, Rachel Baribault Kent
Publikováno v:
Oncogenes in B-Cell Neoplasia ISBN: 9783642698620
The c-myc oncogene has been implicated in a wide spectrum of B cell neoplasias (1–4) Reports of c-myc gene amplification (5), of insertion of viral elements near the c-myc promoter (1), and of point mutations within the c-myc gene (6) have appeared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::348fdd87a5cee92aec9af876461a8a49
https://doi.org/10.1007/978-3-642-69860-6_23
https://doi.org/10.1007/978-3-642-69860-6_23