Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Rachel Anne Goodwin"'
Autor:
Scott R. Berry, Stephanie Snow, Alwin Jeyakumar, Ravi Ramjeesingh, Carolyn Nessim, Timothy R. Asmis, Patrick H McCrea, Jeff Craswell, Satareh Samimi, Mark Doherty, Mario Valdes, Jessica Corbett, Rachel Anne Goodwin, M. Vickers, Dominick Bossé, Thierry Alcindor, Francine Aubin, Erin D. Kennedy, Aamer Mahmud, Angela J Hyde, Michael Lock, Rami Nassabein, Margot J. Burnell, Simron Singh, Wissam Saliba, Derek J. Jonker, Mustapha Tehfe, Luisa Galvis, M. Thirlwell, Rakesh Goel, Vimoj Nair, Mohammed Harb, Ronald Burkes, Colin Brown, Muhammad Asim Raza, Joanna Gotfrit, Nathalie Daaboul, D A Barry Fleming, Stephen Welch, B. Colwell
Publikováno v:
Current Oncology, Vol 28, Iss 185, Pp 1988-2006 (2021)
Current Oncology
Current Oncology
The annual Eastern Canadian Gastrointestinal Cancer Consensus Conference 2019 was held in Morell, Prince Edward Island, 19–21 September 2019. Experts in medical oncology, radiation oncology, and surgical oncology who are involved in the management
Publikováno v:
World Journal of Gastroenterology
Pancreatic cancer remains a leading cause of cancer-related death with few available therapies for advanced disease. Recently, patients with germline BRCA mutations have received increased attention due to advances in the management of BRCA mutated o
Autor:
Janessa Laskin, Laura Williamson, Shehara Mendis, Grainne M. O'Kane, Robert E. Denroche, Jennifer J. Knox, Erica S Tsang, Gun Ho Jang, Marco A. Marra, Jonathan M. Loree, James T. Topham, Steven J.M. Jones, Julie M. Wilson, Patricia A. Tang, Andrew J. Mungall, Daniel J. Renouf, Michael K.C. Lee, Faiyaz Notta, Oliver F. Bathe, David F. Schaeffer, Steven Gallinger, Richard A. Moore, Joanna M Karasinska, Rachel Anne Goodwin, Steve E. Kalloger
Publikováno v:
Clinical Cancer Research. 27:246-254
Purpose: With the rising incidence of early-onset pancreatic cancer (EOPC), molecular characteristics that distinguish early-onset pancreatic ductal adenocarcinoma (PDAC) tumors from those arising at a later age are not well understood. Experimental
Autor:
Janessa Laskin, Jonathan M. Loree, Marco A. Marra, Steven J.M. Jones, James T. Topham, Joanna M. Karasinska, Steven Gallinger, Veronika Csizmok, Julie M. Wilson, Laura Williamson, Steve E. Kalloger, David F. Schaeffer, Daniel J. Renouf, Jennifer J. Knox, Gun Ho Jang, Erica S Tsang, Grainne M. O'Kane, Hui-Li Wong, Andrew J. Mungall, Faiyaz Notta, Michael K.C. Lee, Robert E. Denroche, Patricia A. Tang, Richard A. Moore, Rachel Anne Goodwin, Oliver F. Bathe
Publikováno v:
Clinical Cancer Research. 27:150-157
Purpose: RNA-sequencing–based subtyping of pancreatic ductal adenocarcinoma (PDAC) has been reported by multiple research groups, each using different methodologies and patient cohorts. “Classical” and “basal-like” PDAC subtypes are associa
Autor:
Joao Paulo Solar Vasconcelos, Nan Chen, Dongsheng Tu, Stephanie Yasmin Brule, Rachel Anne Goodwin, Derek J. Jonker, Timothy Jay Price, John Raymond Zalcberg, Malcolm J. Moore, Christos Stelios Karapetis, Lillian L. Siu, Jeremy David Shapiro, John Simes, Christopher J. O'Callaghan, Jonathan M. Loree
Publikováno v:
Journal of Clinical Oncology. 41:124-124
124 Background: Primary tumour location is predictive of anti-EGFR benefit and prognostic in metastatic colorectal cancer (mCRC). Transverse colon cancers are often categorized as right sided, but the optimal cut point is unclear. Canadian Cancer Tri
Autor:
Jose Gerard Monzon, Kurian Joseph, Eric Xueyu Chen, Patricia A. Tang, Rishi Sinha, Kristopher Dennis, Rachel Anne Goodwin, Diane Severin, Jim Dimitroulakos, Michael M. Vickers
Publikováno v:
Journal of Clinical Oncology. 41:131-131
131 Background: Pre-clinical evidence suggest that statins have antiproliferative, proapoptotic, and anti-invasive properties. Also, statins can sensitize cancer tissues and protect normal tissues to the effects of radiation. A standard treatment of
Autor:
Jennifer L. Spratlin, Grainne O´Kane, Rachel Anne Goodwin, Elaine McWhirter, Darby Thompson, Khalif Halani, Michelle Jones, Malcolm Snow, Edward Russell McAllister, Andres Machado, Yasmin Lemmerick, Jim Pankovich
Publikováno v:
Journal of Clinical Oncology. 40:3031-3031
3031 Background: BOLD-100 is a first-in-class ruthenium-based anticancer agent in Phase 1b / 2 clinical development for the treatment of advanced gastrointestinal (GI) cancers in combination with FOLFOX. Being developed primarily as a combinational a
Autor:
Dongsheng Tu, Eitan Amir, Michael Cabanero, Phillipe L. Bedard, John Hilton, Rachel Anne Goodwin, Lesley Seymour, Karen A. Gelmon, Ming Tsao, Diego Villa, Stephen Chia
Publikováno v:
The Oncologist. 24:1439-1445
BackgroundImmune checkpoint inhibitors are active in a broad range of cancers, including programmed death ligand 1 (PD-L1)-positive, triple-negative, metastatic breast cancer (MBC). Antibody-dependent cell-mediated cytotoxicity is a mechanism of acti
Autor:
Mark Clemons, Rachel Anne Goodwin, A Imbulgoda, Tharshika Thangarasa, Patricia A. Tang, Joanna Gotfrit, Michael M. Vickers
Publikováno v:
Current Oncology. 26:162-166
Background The optimal management of hypomagnesemia (hMg) induced by epidermal growth factor receptor inhibitors (egfris) for advanced colorectal cancer is unclear. We surveyed gastrointestinal medical oncologists in Canada to determine practice patt
Autor:
Allen M. Gown, Daniel W. Yokom, Rachel Anne Goodwin, Derek J. Jonker, Justin Bateman, Horia Marginean, Esmeralda C. Marginean, Manijeh Daneshmand, Timothy R. Asmis, Shelly Sud, Joanna Gotfrit
Publikováno v:
Translational Oncology, Vol 14, Iss 2, Pp 100996-(2021)
Translational Oncology
Translational Oncology
Highlights • STAT3 regulates genes for cell growth and differentiation, inflammation, neoplasia. • STAT3 is a potential therapeutic target in colorectal cancer. • Most liver metastases stain STAT3 positive. • Discordant pSTAT3 expression in p