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pro vyhledávání: '"Rachel Ann Bibby"'
Autor:
Andrew J. Thompson, Julian Blagg, Meirion Richards, Rachel Ann Bibby, Fiona C. Rowan, Richard Bayliss
Publikováno v:
ACS Chemical Biology
Most protein kinases are regulated through activation loop phosphorylation, but the contributions of individual sites are largely unresolved due to insufficient control over sample phosphorylation. Aurora-A is a mitotic Ser/Thr protein kinase that ha
Autor:
Spiros Linardopoulos, Chan Tang, Richard Bayliss, Amir Faisal, Konstantinos Drosopoulos, Steven J. Lubbe, Richard S. Houlston, Rachel Ann Bibby
Publikováno v:
The Journal of biological chemistry. 284(48)
Mutations in protein kinases can drive cancer through alterations of the kinase activity or by uncoupling kinase activity from regulation. Changes to protein expression in Aurora A, a mitotic Ser/Thr kinase, are associated with the development of sev