Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Rachel A. Stephenson"'
Autor:
Lantian Lu, Wei Yang Kong, Jiahui Zhang, Farrhana Firdaus, James W. Wells, Rachel J. Stephenson, Istvan Toth, Mariusz Skwarczynski, Jazmina L. Gonzalez Cruz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Subunit vaccines hold substantial promise in controlling infectious diseases, due to their superior safety profile, specific immunogenicity, simplified manufacturing processes, and well-defined chemical compositions. One of the most important end-tar
Externí odkaz:
https://doaj.org/article/9d05d7bec5f34cd5a012036e2a7970cf
Publikováno v:
Vaccines, Vol 12, Iss 3, p 272 (2024)
Group A Streptococcus (GAS), or Streptococcus pyogenes, is a gram-positive bacterium that extensively colonises within the human host. GAS is responsible for causing a range of human infections, such as pharyngitis, impetigo, scarlet fever, septicemi
Externí odkaz:
https://doaj.org/article/2ee18372f7c142c88a12cfeb863613de
Autor:
Farrhana Z. Firdaus, Stacey Bartlett, Waleed M. Hussein, Lantian Lu, Quentin Wright, Wenbin Huang, Ummey J. Nahar, Jieru Yang, Mattaka Khongkow, Margaret Veitch, Prashamsa Koirala, Uracha R. Ruktanonchai, Michael J. Monteiro, Jazmina L. Gonzalez Cruz, Rachel J. Stephenson, James W. Wells, Istvan Toth, Mariusz Skwarczynski
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 602 (2023)
Human papilloma virus (HPV) is responsible for all cases of cervical cancer. While prophylactic vaccines are available, the development of peptide-based vaccines as a therapeutic strategy is still under investigation. In comparison with the tradition
Externí odkaz:
https://doaj.org/article/35974cd5d89e46b9a256e6e6ba570ed1
Autor:
Jingyi Fan, Shengbin Jin, Lachlan Gilmartin, Istvan Toth, Waleed M. Hussein, Rachel J. Stephenson
Publikováno v:
Vaccines, Vol 10, Iss 7, p 1120 (2022)
Vaccines are one of the most significant medical interventions in the fight against infectious diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the worldwide transmission to eradication levels of infectious diseases, in
Externí odkaz:
https://doaj.org/article/c8c8e0230fc047869910b6cd6a9c20d1
Autor:
Torey R Arnold, Joseph H Shawky, Rachel E Stephenson, Kayla M Dinshaw, Tomohito Higashi, Farah Huq, Lance A Davidson, Ann L Miller
Publikováno v:
eLife, Vol 8 (2019)
Cellular forces sculpt organisms during development, while misregulation of cellular mechanics can promote disease. Here, we investigate how the actomyosin scaffold protein anillin contributes to epithelial mechanics in Xenopus laevis embryos. Increa
Externí odkaz:
https://doaj.org/article/b2e8d36113274923811bc67c9beb8534
Autor:
Rachel J. Stephenson, Istvan Toth
Publikováno v:
Journal of Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c924988c70ff83f0fc39d19bcef5b8ba
https://doi.org/10.1021/acs.jmedchem.3c00366
https://doi.org/10.1021/acs.jmedchem.3c00366
Autor:
Jiahui Zhang, Jingyi Fan, Mariusz Skwarczynski, Rachel J Stephenson, Istvan Toth, Waleed M Hussein
Publikováno v:
International Journal of Nanomedicine. 17:869-900
Persistent infection with high-risk human papillomaviruses (HPVs), such as HPV-16 and HPV-18, can induce cervical cancer in humans. The disease carries high morbidity and mortality among females worldwide. Inoculation with prophylactic HPV vaccines,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3559d6e8b165f0e5b54d443fcade7d
https://doi.org/10.2147/ijn.s269986
https://doi.org/10.2147/ijn.s269986
Autor:
Harrison Y. R. Madge, Istvan Toth, Robert J. Capon, Zeinab G. Khalil, Rachel J. Stephenson, Wenbin Huang, Viviene S. Santiago, Prashamsa Koirala, Waleed M. Hussein, Berta Rigau-Planella, Lachlan Gilmartin
Publikováno v:
Biomaterials Science. 10:281-293
Untreated or reoccurring group A Streptococcus (GAS) infection can lead to a number of post-infection complications, including rheumatic heart disease. There is no licenced vaccine for the treatment or prevention of GAS infection. We identified that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26361d0592218ce349924c0cabe03e15
https://doi.org/10.1039/d1bm01333e
https://doi.org/10.1039/d1bm01333e
Autor:
Chuankai Dai, Zeinab G. Khalil, Waleed M. Hussein, Jieru Yang, Xiumin Wang, Lili Zhao, Robert J. Capon, Istvan Toth, Rachel J. Stephenson
Publikováno v:
Vaccines, Vol 8, Iss 2, p 210 (2020)
Group A Streptococcus (GAS) and GAS-associated infections are a global challenge, with no licensed GAS vaccine on the market. The GAS M protein is a critical virulence factor in the fight against GAS infection, and it has been a primary target for GA
Externí odkaz:
https://doaj.org/article/3d6d3d84b0f94038a44a567696ba6f10