Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Rachel A. Silverstein"'
Autor:
Lin Zhao, Sabrina R. T. Koseki, Rachel A. Silverstein, Nadia Amrani, Christina Peng, Christian Kramme, Natasha Savic, Martin Pacesa, Tomás C. Rodríguez, Teodora Stan, Emma Tysinger, Lauren Hong, Vivian Yudistyra, Manvitha R. Ponnapati, Joseph M. Jacobson, George M. Church, Noah Jakimo, Ray Truant, Martin Jinek, Benjamin P. Kleinstiver, Erik J. Sontheimer, Pranam Chatterjee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract CRISPR enzymes require a defined protospacer adjacent motif (PAM) flanking a guide RNA-programmed target site, limiting their sequence accessibility for robust genome editing applications. In this study, we recombine the PAM-interacting doma
Externí odkaz:
https://doaj.org/article/c6eaa1afc2b34657a91e037a58ba1052
Autor:
Saranya A. Sethuraman, Rachel S. Silverstein, Nicket Dedhia, Adam C. Shaner, David E. Asprinio
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background Injuries of the tarsometatarsal joint complex ranging from purely ligamentous to multidirectionally unstable midfoot fracture-dislocations are anatomically fixed to minimize long-term sequelae including post-traumatic arthritis, p
Externí odkaz:
https://doaj.org/article/b6ce4a9bb6d24f56836fb0b961cb0744
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-7 (2021)
Abstract The human microbiome refers to the genetic composition of microorganisms in a particular location in the human body. Emerging evidence over the past many years suggests that the microbiome constitute drivers of human fate almost at par with
Externí odkaz:
https://doaj.org/article/dfbdfcef32154bf7b04c5b4e016f9fff
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The human decidua and placenta form a distinct environment distinguished for its promotion of immunotolerance to infiltrating semiallogeneic trophoblast cells to enable successful pregnancy. The maternal-fetal interface also successfully precludes tr
Externí odkaz:
https://doaj.org/article/ee05ca74c05341ed8af2e9227d3d87a5
Autor:
Rachel S, Silverstein, Daniel D, Wang, Lee S, Haruno, Timothy E, Lotze, Allison C, Scott, Scott B, Rosenfeld
Publikováno v:
Journal of Pediatric Orthopaedics. 43:e163-e167
Collagen VI-related myopathies with pathologic COL6A1, COL6A2, and COL6A3 variants manifest as a phenotypic continuum of rare disorders, including Bethlem myopathy (BM), characterized by early onset muscle weakness, proximal joint contractures, and d
Autor:
Kathleen A. Christie, Jimmy A. Guo, Rachel A. Silverstein, Roman M. Doll, Megumu Mabuchi, Hannah E. Stutzman, Jiecong Lin, Linyuan Ma, Russell T. Walton, Luca Pinello, G. Brett Robb, Benjamin P. Kleinstiver
Publikováno v:
Nature Biotechnology. 41:409-416
Publikováno v:
Arthroscopy Techniques. 11:e1811-e1816
Surgical treatment of radial tears in the junction of the anterior horn and body of the lateral meniscus is indicated in the acute setting and with failure of nonoperative therapy. There are several options for arthroscopic repair; however, these are
Autor:
Borja Alonso-Lerma, Ylenia Jabalera, Sara Samperio, Matias Morin, Almudena Fernandez, Logan T. Hille, Rachel A. Silverstein, Ane Quesada-Ganuza, Antonio Reifs, Sergio Fernández-Peñalver, Yolanda Benitez, Lucia Soletto, Jose A. Gavira, Adrian Diaz, Wim Vranken, Avencia Sanchez-Mejias, Marc Güell, Francisco J. M. Mojica, Benjamin P. Kleinstiver, Miguel A. Moreno-Pelayo, Lluis Montoliu, Raul Perez-Jimenez
Publikováno v:
Nat Microbiol
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9 is an effector protein that targets invading DNA and plays a major role in the prokaryotic adaptive immune system. Although Streptococcus pyogenes CRISPR–Cas9 has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53d8df2c46392fb5741544f0f76fd3d
https://doi.org/10.1038/s41564-022-01265-y
https://doi.org/10.1038/s41564-022-01265-y
Autor:
Jessica A, McGraw-Heinrich, Ekene U, Ezeokoli, Parker, Mitchell, Rachel S, Silverstein, Brian G, Smith
Publikováno v:
Journal of Pediatric Orthopaedics B.
The purposeof this study was to compare outcomes of operatively treated pediatric distal third tibial shaft fractures fixed with elastic nailing or plate fixation and to evaluate the incidence of concurrent distal tibia physeal fractures. Retrospecti
Publikováno v:
Techniques in Orthopaedics. 37:280-282