Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Rachel A. Lynch"'
Autor:
Alexandra Schäfer, Sarah R. Leist, Lisa E. Gralinski, David R. Martinez, Emma S. Winkler, Kenichi Okuda, Padraig E. Hawkins, Kendra L. Gully, Rachel L. Graham, D. Trevor Scobey, Timothy A. Bell, Pablo Hock, Ginger D. Shaw, Jennifer F. Loome, Emily A. Madden, Elizabeth Anderson, Victoria K. Baxter, Sharon A. Taft-Benz, Mark R. Zweigart, Samantha R. May, Stephanie Dong, Matthew Clark, Darla R. Miller, Rachel M. Lynch, Mark T. Heise, Roland Tisch, Richard C. Boucher, Fernando Pardo Manuel de Villena, Stephanie A. Montgomery, Michael S. Diamond, Martin T. Ferris, Ralph S. Baric
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Infectious diseases have shaped the human population genetic structure, and genetic variation influences the susceptibility to many viral diseases. However, a variety of challenges have made the implementation of traditional human Genome-wid
Externí odkaz:
https://doaj.org/article/0653e049732d4652b9b825ecba93c24d
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1729-1737 (2019)
Trichloroethylene (TCE) and inorganic arsenic (iAs) are environmental contaminants that can target the kidney. Chronic exposure to TCE is associated with increased incidence of renal cell carcinoma, while co-exposure to TCE and iAs likely occurs in e
Externí odkaz:
https://doaj.org/article/4a72a1a94088405bb471235635763cbe
Autor:
Paul A. Nakonezny, Yuliang Hu, Paul E. Croarkin, Rachel L. Lynch, Chris Wang, Julia Shekunov, Magdalena Romanowicz, Arjun P. Athreya, Valeria Melo, Chelsea M. Ale
Publikováno v:
J Child Adolesc Psychopharmacol
Objective: Parent–child interaction therapy (PCIT) is an evidence-based approach for children aged 2–7 years with disruptive behavior problems. This study examined the effectiveness of PCIT with and without concurrent pharmacotherapy. Methods: A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f713e9a255794613561c88ad148997a
https://doi.org/10.1089/cap.2021.0043
https://doi.org/10.1089/cap.2021.0043
Autor:
Bin Gu, Noah G. Levine, Wenjing Xu, Rachel M. Lynch, Fernando Pardo-Manuel de Villena, Benjamin D. Philpot
Publikováno v:
Brain Communications. 4
Sudden unexpected death in epilepsy is the most catastrophic outcome of epilepsy. Each year there are as many as 1.65 cases of such death for every 1000 individuals with epilepsy. Currently, there are no methods to predict or prevent this tragic even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2490cb1f4ad95d9f51ad426ff92e9a12
https://doi.org/10.1093/braincomms/fcac073
https://doi.org/10.1093/braincomms/fcac073
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1729-1737 (2019)
G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1729-1737 (2019)
Trichloroethylene (TCE) and inorganic arsenic (iAs) are environmental contaminants that can target the kidney. Chronic exposure to TCE is associated with increased incidence of renal cell carcinoma, while co-exposure to TCE and iAs likely occurs in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4052148feb24bf327bfe87d795db790
http://europepmc.org/articles/PMC6505147
http://europepmc.org/articles/PMC6505147
BackgroundBeta-catenin (CTNNB1) is a key downstream effector of the WNT signaling pathway that is involved in embryonic development and tumorigenesis. To further study the role of CTNNB1 in gut tumorigenesis, mice carrying a conditional, stabilizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e0ce34a049bd23bbd553af99980bd2b
https://doi.org/10.21203/rs.3.rs-88503/v1
https://doi.org/10.21203/rs.3.rs-88503/v1
Autor:
Martin T. Ferris, Sarah A. Schoenrock, Timothy R. Gershon, David B. Darr, Mark J. Zylka, J. Mauro Calabrese, James E. Faber, Laura G. Reinholdt, David W. Threadgill, John R. Shorter, Kathleen M. Caron, Lisa E. Gralinski, Robert S. Hagan, Glenn K. Matsushima, Yuyu Ren, Christopher M. Sassetti, Christiann H. Gaines, Bin Gu, Lori L. O'Brien, Sheryl S. Moy, Timothy A. Bell, Keegan Wardwell, Barbara J. Vilen, Terry Magnuson, Darla R. Miller, Clare M. Smith, Abraham A. Palmer, A. Wesley Burks, Fernando Pardo-Manuel de Villena, Celine L. St. Pierre, William Valdar, Rachel C. McMullan, Pablo Hock, Frank L. Conlon, Kevin C K Lloyd, Gudrun A. Brockmann, Anwica Kashfeen, Ginger D. Shaw, Steve Rockwood, Karen L. Mohlke, Matthew Blanchard, Alessandra Livraghi-Butrico, Benjamin D. Philpot, Rachel M Lynch, Scott H. Randell, J. Brennan, John Sebastian Sigmon, Vivek Kumar, Ralph S. Baric, Leonard McMillan, Mark T. Heise, Ernest G. Heimsath, Richard E. Cheney, Avani Saraswatula, Lucy H. Williams, Allison R. Rogala, Colton L. Linnertz, Caroline E. Y. Murphy, Dominic Ciavatta, Mike Kulis, Tal Kafri, Craig L. Franklin, Jason K. Whitmire, J. Charles Jennette, Maya L. Najarian, Cathleen M. Lutz, Jonathan C. Schisler, Lisa M. Tarantino, Folami Y. Ideraabdullah
Publikováno v:
Genetics: a periodical record of investigations bearing on heredity and variation, vol 216, iss 4
Genetics
Genetics
The laboratory mouse is the most widely used animal model for biomedical research, due in part to its well-annotated genome, wealth of genetic resources, and the ability to precisely manipulate its genome. Despite the importance of genetics for mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f021d31a7f2e88239f86551bdc6e73b
https://escholarship.org/uc/item/7cq7g4tc
https://escholarship.org/uc/item/7cq7g4tc
Autor:
Kranti Konganti, Erica S. Rinella, Ming Yu, Kathryn R Anderson, Jorge Jaimes-Alvarado, David W. Threadgill, Rachel M Lynch, Amie Perry, Carolina Mantilla-Rojas, Evann J Bourgeois, Estefania Barba
Publikováno v:
Oncogene
Although epidermal growth factor receptor (EGFR)-targeted therapies are approved for colorectal cancer (CRC) treatment, only 15% of CRC patients respond to EGFR inhibition. Here, we show that colorectal cancers (CRC) can initiate and grow faster thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f764c445cd0893d1adacfbd68e3328
https://pubmed.ncbi.nlm.nih.gov/33767440
https://pubmed.ncbi.nlm.nih.gov/33767440
Autor:
Christiann H. Gaines, Sheryl S. Moy, Mark T. Heise, Scott H. Randell, Matthew Blanchard, Vivek Kumar, Leonard McMillan, Darla R. Miller, Lucy H. Williams, Timothy A. Bell, Keegan Wardwell, Terry Magnuson, Mark J. Zylka, Christopher M. Sassetti, Craig L. Franklin, Ralph S. Baric, Sarah A. Schoenrock, Glenn K. Matsushima, Cathleen M. Lutz, James E. Faber, Maya L. Najarian, Yuyu Ren, Folami Y. Ideraabdullah, Jason K. Whitmire, Bin Gu, Jonathan C. Schisler, Pablo Hock, J. Charles Jennette, Celine L. St. Pierre, Lisa M. Tarantino, Samir N. P. Kelada, Karen L. Mohlke, Laura G. Reinholdt, Alessandra Livraghi-Butrico, Richard F. Loeser, Abraham A. Palmer, Robert S. Hagan, John R. Shorter, David W. Threadgill, Lori L. O'Brien, Kathleen M. Caron, Steve Rockwood, Kent Lloyd, Fernando Pardo-Manuel de Villena, Caroline E. Y. Murphy, A. Wesley Burks, Tal Kafri, Benjamin D. Philpot, David B. Darr, Avani Saraswatula, Ernest G. Heimsath, Richard E. Cheney, Allison R. Rogala, William Valdar, Dominic Ciavatta, Rachel C. McMullan, Ginger D. Shaw, Clare M. Smith, Frank L. Conlon, Barbara J. Vilen, John Sebastian Sigmon, Gudrun A. Brockmann, Anwica Kashfeen, Martin T. Ferris, Rachel M Lynch, Mauro Calabrese, Colton L. Linnertz, Timothy R. Gershon, J. Brennan, Lisa E. Gralinski, Mike Kulis
The laboratory mouse is the most widely used animal model for biomedical research, due in part to its well annotated genome, wealth of genetic resources and the ability to precisely manipulate its genome. Despite the importance of genetics for mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d2895cb1fd85eea8a9b4a24d854cc2
https://doi.org/10.1101/2020.03.12.989400
https://doi.org/10.1101/2020.03.12.989400
Autor:
Mark L. Wolraich, Eugenia Chan, Tanya Froehlich, Rachel L. Lynch, Ami Bax, Susan T. Redwine, Demvihin Ihyembe, Joseph F. Hagan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42d9a06eaa1f186f306041e57c2a9e0f
https://doi.org/10.1542/9781610024129-part01-adhd
https://doi.org/10.1542/9781610024129-part01-adhd