Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rachel A. Haggerty"'
Autor:
Samuel C Wolff, Katarzyna M Kedziora, Raluca Dumitru, Cierra D Dungee, Tarek M Zikry, Adriana S Beltran, Rachel A Haggerty, JrGang Cheng, Margaret A Redick, Jeremy E Purvis
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 9, Pp 1-9 (2018)
Abstract It is well known that clonal cells can make different fate decisions, but it is unclear whether these decisions are determined during, or before, a cell's own lifetime. Here, we engineered an endogenous fluorescent reporter for the pluripote
Externí odkaz:
https://doaj.org/article/ce877a86d66346a5a7021a2bb8a4c608
Autor:
Rachel A Haggerty, Jeremy E Purvis
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 12, Pp 1-3 (2017)
Abstract Molecular mechanisms are often described using “word models”—phrases intended to capture the interactions in a biological process. In their recent work, Sorger and colleagues (Gyori et al, 2017) provide a framework for converting word
Externí odkaz:
https://doaj.org/article/826fc7762d194de482121cf1536304d2
Autor:
Rachel A. Haggerty, Jeremy E. Purvis
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008657 (2021)
PLoS Computational Biology
PLoS Computational Biology
Individual cells show variability in their signaling dynamics that often correlates with phenotypic responses, indicating that cell-to-cell variability is not merely noise but can have functional consequences. Based on this observation, we reasoned t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bcae71e0bc0334dc44a3b9bb8012f4
https://doaj.org/article/4da3a99e83a141f7b08bc5cef5c4561a
https://doaj.org/article/4da3a99e83a141f7b08bc5cef5c4561a
Autor:
Katarzyna M. Kedziora, Raluca Dumitru, Jeremy E. Purvis, Samuel C. Wolff, Margaret A. Redick, Rachel A. Haggerty, Tarek M. Zikry, JrGang Cheng, Cierra D. Dungee, Adriana S. Beltran
Publikováno v:
Molecular Systems Biology
It is well known that clonal cells can make different fate decisions, but it is unclear whether these decisions are determined during, or before, a cell's own lifetime. Here, we engineered an endogenous fluorescent reporter for the pluripotency facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db641c5bad240a65b5f9ee948e3489ae
https://doi.org/10.15252/msb.20178140
https://doi.org/10.15252/msb.20178140
Autor:
Samuel C. Wolff, Hong Yi, Hui Xiao Chao, Rachel A. Haggerty, Gavin D. Grant, Katarzyna M. Kedziora, Jayashree Kumar, David Borland, Jeanette Gowen Cook, Jeremy E. Purvis
Summary The cell cycle is driven by precise temporal coordination among many molecular activities. To understand and explore this process, we developed the Cell Cycle Browser (CCB), an interactive web interface based on real-time reporter data collec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7d1916bdf314ab5555250c0497bea5
https://doi.org/10.1101/234039
https://doi.org/10.1101/234039
Autor:
Cierra D. Dungee, Adriana S. Beltran, Raluca Dumitru, Katarzyna M. Kedziora, Samuel C. Wolff, JrGang Cheng, Tarek M. Zikry, Jeremy E. Purvis, Rachel A. Haggerty
Clonal cells can make different fate decisions, but it is often unclear to what extent these decisions are autonomous or predetermined. Here, we introduce a live-cell reporter for the pluripotency factor OCT4 into human embryonic stem cells to unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03749a56900f3368e069dda9ddc1110
https://doi.org/10.1101/137299
https://doi.org/10.1101/137299
Autor:
Kerry Bloom, Elaine Yeh, Prashant K. Mishra, Andrew D. Stephens, Russell M. Taylor, Cory Quammen, Julian Haase, Munira A. Basrai, Rachel A. Haggerty
Publikováno v:
Current Biology. 23(19):1939-1944
SummaryThe budding yeast kinetochore is ∼68 nm in length with a diameter slightly larger than a 25 nm microtubule [1]. The kinetochores from the 16 chromosomes are organized in a stereotypic cluster encircling central spindle microtubules. Quantita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148989132e7a9aa44aeaa3514029ca92
Autor:
Andrew D. Stephens, Chloe E. Snider, Julian Haase, M. Gregory Forest, Paula A. Vasquez, Rachel A. Haggerty, Kerry Bloom
Publikováno v:
The Journal of Cell Biology
During mitosis, cohesin and condensin cross-link pericentromeres of different chromosomes to coordinate centromere attachment sites.
The mitotic segregation apparatus composed of microtubules and chromatin functions to faithfully partition a dup
The mitotic segregation apparatus composed of microtubules and chromatin functions to faithfully partition a dup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68aad28e4336b85daf0e453aeeaefc13
http://europepmc.org/articles/PMC3824013
http://europepmc.org/articles/PMC3824013
Autor:
Jeremy E. Purvis, Rachel A. Haggerty, Dileep Varma, Kristen D Brantley, Kate E. Coleman, Jeanette Gowen Cook, Anindya Dutta, Etsuko Shibata, Gavin D. Grant, Benjamin D. Workman
Publikováno v:
Genesdevelopment. 29(16)
Timely ubiquitin-mediated protein degradation is fundamental to cell cycle control, but the precise degradation order at each cell cycle phase transition is still unclear. We investigated the degradation order among substrates of a single human E3 ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe3cb57f2c07ebd3728f677cac0d2db
https://pubmed.ncbi.nlm.nih.gov/26272819
https://pubmed.ncbi.nlm.nih.gov/26272819