Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Rachel A Gioscia-Ryan"'
Autor:
Abigail G Casso, Rachel A Gioscia-Ryan, Zachary J Sapinsley, Nicholas S VanDongen, Amy E Bazzoni, Andrew P Neilson, Melanie C Zigler, Kevin P Davy, Douglas R Seals, Vienna E Brunt
Publikováno v:
Artery Research, Vol 26, Iss Supplement 1 (2020)
Age-related increases in aortic stiffness, assessed by pulse wave velocity (PWV), predict cardiovascular (CV)-related mortality, but the upstream drivers are incompletely understood. Purpose: To determine if higher circulating levels of the gut micr
Externí odkaz:
https://doaj.org/article/3a8b1dee1b01463e9bc2d518fbf70fdf
Autor:
Benjamin J. Ryan, Douglas W. VanPelt, Lisa M. Guth, Alison C. Ludzki, Rachel A. Gioscia‐Ryan, Chiwoon Ahn, Katherine L. Foug, Jeffrey F. Horowitz
Publikováno v:
Experimental Physiology, Vol 103, Iss 11, Pp 1443-1447 (2018)
New Findings What is the central question of this study? Do obese women with relatively high whole‐body iron stores exhibit elevated in vivo rates of fatty acid (FA) release from adipose tissue compared with a well‐matched cohort of obese women w
Externí odkaz:
https://doaj.org/article/7608d1182bb64954a8a4ee493bf57675
Autor:
Abigail G. Casso, Nicholas S. VanDongen, Rachel A. Gioscia‐Ryan, Zachary S. Clayton, Nathan T. Greenberg, Brian P. Ziemba, David A. Hutton, Andrew P. Neilson, Kevin P. Davy, Douglas R. Seals, Vienna E. Brunt
Publikováno v:
J Physiol
Vascular dysfunction: develops progressively with ageing; increases the risk of cardiovascular diseases (CVD); and is characterized by endothelial dysfunction and arterial stiffening, which are primarily mediated by superoxide-driven oxidative stress
Autor:
Vienna E. Brunt, Nathan T. Greenberg, Zachary J. Sapinsley, Abigail G. Casso, James J. Richey, Nicholas S. VanDongen, Rachel A. Gioscia-Ryan, Brian P. Ziemba, Andrew P. Neilson, Kevin P. Davy, Douglas R. Seals
Publikováno v:
Journal of Applied Physiology. 133:798-813
We provide novel evidence that increased circulating concentrations of the gut microbiome-derived metabolite trimethylamine N-oxide (TMAO) contribute to vascular dysfunction associated with consumption of a Western-style diet and that this dysfunctio
Autor:
Amy E Bazzoni, Andrew P. Neilson, Abigail G. Casso, Vienna E. Brunt, Melanie C. Zigler, Douglas R. Seals, David A. Hutton, James J Richey, Zachary J Sapinsley, Zachary S. Clayton, Kevin P. Davy, Brian P. Ziemba, Nicholas S. VanDongen, Rachel A. Gioscia-Ryan
Publikováno v:
Hypertension. 78:499-511
Aging is associated with stiffening of the large elastic arteries and consequent increases in systolic blood pressure (SBP), which together increase cardiovascular disease risk; however, the upstream mechanisms are incompletely understood. Using comp
Autor:
Pedro L, Valenzuela, Manuel, Mateo-March, Xabier, Muriel, Mikel, Zabala, Alejandro, Lucia, David, Barranco-Gil, Grégoire P, Millet, Franck, Brocherie, Johannes, Burtscher, Martin, Burtscher, Benjamin J, Ryan, Rachel A, Gioscia-Ryan, Stephane, Perrey, Víctor, Rodrigo-Carranza, Fernando, González-Mohíno, José María, González-Ravé, Jordan, Santos-Concejero, Benedito S, Denadai, Camila C, Greco, Arturo, Casado, Carl, Foster, Raffaele, Mazzolari, Giulia Nicole, Baldrighi, Elisa, Pastorio, Davide, Malatesta, Aurélien, Patoz, Fabio, Borrani, Stephen J, Ives, Justin A, DeBlauw, Ricardo, Dantas de Lucas, Fernando Klitzke, Borszcz, Eduardo Marcel, Fernandes Nascimento, Luiz Guilherme, Antonacci Guglielmo, Tiago, Turnes, Richard T, Jaspers, Stephan, van der Zwaard, Romuald, Lepers, Julien, Louis, Anderson, Meireles, Hiago L. R., de Souza, Géssyca T, de Oliveira, Marcelo P, dos Santos, Rhaí A, Arriel, Moacir, Marocolo, B, Hunter, S, Meyler, D, Muniz-Pumares, Renato M, Ferreira, Abigail S, Sogard, Stephen J, Carter, Timothy D, Mickleborough, Guilherme Pereira, Saborosa, Raphael Dinalli, de Oliveira Freitas, Paula Souza, Alves dos Santos, João Pedro, de Souza Ferreira, Francisco, de Assis Manoel, Sandro Fernandes, da Silva, Christoph, Triska, Bettina, Karsten, Dajo, Sanders, Elliot S, Lipksi, David J, Spindler, Matthijs K. C., Hesselink, Rodrigo, Zacca, Márcio Fagundes, Goethel, David Bruce, Pyne, Brayden M, Wood, Peyton E, Allen, Jaden L, Gabelhausen, Alexandra M, Keller, Mast T, Lige, Alicia S, Oumsang, Greg L, Smart, Hunter L, Paris, Arthur H, Dewolf, Guillaume, Toffoli, Borja, Martinez-Gonzalez, Samuele M, Marcora, Daniela, Terson de Paleville, Ricardo J, Fernandes, Susana M, Soares, J. Arturo, Abraldes, Guilherme, Matta, Arthur Henrique, Bossi, D G, McCarthy, W, Bostad, J, Gibala, Mary, Vagula
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 133(1)
Autor:
Natalie E. Poliektov, Matthew J. Rossman, Douglas R. Seals, Kara L. Lubieniecki, Nathan S. Bryan, Amy L. Sindler, Lawrence C. Johnson, Angelo D'Alessandro, Nina Z. Bispham, Erzsebet E. Nagy, Rachel A. Gioscia-Ryan, Julie A. Reisz, Brian P. Ziemba, Kayla A. Woodward, Jessica R. Santos-Parker, Michel Chonchol
Publikováno v:
Hypertension
To determine the efficacy of inorganic nitrite supplementation on endothelial function in humans and mechanisms of action, we performed (1) a randomized, placebo-controlled, parallel-group clinical trial with sodium nitrite (80 mg/day, 12 weeks) in o
Autor:
Rachel A. Gioscia-Ryan, Zachary S. Clayton, Nicholas S. VanDongen, Brian P. Ziemba, Matthew J. Rossman, David A. Hutton, Micah L. Battson, Melanie C. Zigler, James J Richey, Lauren M. Cuevas, Douglas R. Seals
Publikováno v:
J Physiol
KEY POINTS The results of the present study establish the temporal pattern of age-related vascular dysfunction across the adult lifespan in sedentary mice consuming a non-Western diet, and the underlying mechanisms The results demonstrate that consum
Autor:
Jenna B. Gillen, Michael W. Schleh, Rachel A. Gioscia-Ryan, Cheehoon Ahn, Thomas L. Chenevert, Alison C. Ludzki, Jeffrey F. Horowitz, Katherine L. Foug, Benjamin J. Ryan
Publikováno v:
Exp Physiol
New findings What is the central question of this study? Obesity is associated with complex perturbations to iron homeostasis: is plasma ferritin concentration (a biomarker of whole-body iron stores) related to the abundance of ferritin (the key tiss
Autor:
Vienna E. Brunt, Andrew P. Neilson, Kevin P. Davy, Douglas R. Seals, Zachary J Sapinsley, Rachel A. Gioscia-Ryan, Brian P. Ziemba, Nicholas S. VanDongen, Abigail G. Casso, Melanie C. Zigler, James J Richey
Publikováno v:
Hypertension. 76:101-112
Age-related vascular endothelial dysfunction is a major antecedent to cardiovascular diseases. We investigated whether increased circulating levels of the gut microbiome-generated metabolite trimethylamine-N-oxide induces endothelial dysfunction with