Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rachel, Ulferts"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100903- (2021)
Summary: Determining how hematopoietic stem and progenitor cells (HSPCs) can be infected by viruses is necessary to understand and predict how the immune system will drive the host response. We present here a protocol to analyze the capacity of SARS-
Externí odkaz:
https://doaj.org/article/c23222a5106946579e969b824591faf8
Autor:
Lewis Timimi, Carmen Figueras-Novoa, Elena Marcassa, Oliver Florey, J Kenneth Baillie, Rupert Beale, Rachel Ulferts
Publikováno v:
Autophagy
Conjugation of the Atg8 (autophagy related 8) family of ubiquitin-like proteins to phospholipids of the phagophore is a hallmark of macroautophagy/autophagy. Consequently, Atg8 family members, especially LC3B, are commonly used as a marker of autopha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553782a03734b1bb4c940e082e70a2aa
https://pubmed.ncbi.nlm.nih.gov/35258397
https://pubmed.ncbi.nlm.nih.gov/35258397
Autor:
Jeroen R.P.M. Strating, Lonneke van der Linden, Lucian Albulescu, Joëlle Bigay, Minetaro Arita, Leen Delang, Pieter Leyssen, Hilde M. van der Schaar, Kjerstin H.W. Lanke, Hendrik Jan Thibaut, Rachel Ulferts, Guillaume Drin, Nina Schlinck, Richard W. Wubbolts, Navdar Sever, Sarah A. Head, Jun O. Liu, Philip A. Beachy, Maria A. De Matteis, Matthew D. Shair, Vesa M. Olkkonen, Johan Neyts, Frank J.M. van Kuppeveld
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 600-615 (2015)
Itraconazole (ITZ) is a well-known antifungal agent that also has anticancer activity. In this study, we identify ITZ as a broad-spectrum inhibitor of enteroviruses (e.g., poliovirus, coxsackievirus, enterovirus-71, rhinovirus). We demonstrate that I
Externí odkaz:
https://doaj.org/article/bf5c36a32e6b4b4f8255f844489c246c
Autor:
Berta Canal, Tom D Deegan, Karim Labib, Agustina P Bertolin, Rupert Beale, John F.X. Diffley, Florian Weissmann, Michael Howell, Ryo Fujisawa, Mary Wu, Lucy S. Drury, Rachel Ulferts, Allison W McClure, Jingkun Zeng
Publikováno v:
Biochemical Journal
SummarySARS-CoV-2 is responsible for COVID-19, a human disease that has caused over 2 million deaths, stretched health systems to near-breaking point and endangered the economies of countries and families around the world. Antiviral treatments to com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3c0762d3a6f4930c63db5b106f20b7
http://europepmc.org/articles/PMC8286823
http://europepmc.org/articles/PMC8286823
Autor:
Kang Wei Tan, Emma L. Roberts, Tiffany Mak, Lucy S. Drury, Souradeep Basu, Berta Canal, Michael Howell, Joseph F. Curran, Florian Weissmann, Karim Labib, Tom D Deegan, John F.X. Diffley, Allison W McClure, Ryo Fujisawa, Mary Wu, Victoria H. Cowling, Rachel Ulferts, Clovis Basier, Rupert Beale, Theresa U. Zeisner, Chew Theng Lim
Publikováno v:
Biochemical Journal
The COVID-19 pandemic has presented itself as one of the most critical public health challenges of the century, with SARS-CoV-2 being the third member of the Coronaviridae family to cause a fatal disease in humans. There is currently only one antivir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74acc162b19fe84f371a9c793c9d9297
http://europepmc.org/articles/PMC8286817
http://europepmc.org/articles/PMC8286817
Autor:
Chew Theng Lim, Kang Wei Tan, Mary Wu, Rachel Ulferts, Lee A. Armstrong, Eiko Ozono, Lucy S. Drury, Jennifer C. Milligan, Theresa U. Zeisner, Jingkun Zeng, Florian Weissmann, Berta Canal, Ganka Bineva-Todd, Michael Howell, Nicola O'Reilly, Rupert Beale, Yogesh Kulathu, Karim Labib, John F.X. Diffley
Publikováno v:
Biochemical Journal
The COVID-19 pandemic has emerged as the biggest life-threatening disease of this century. Whilst vaccination should provide a long-term solution, this is pitted against the constant threat of mutations in the virus rendering the current vaccines les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc295ebc783870d82ca11f9dd713752
http://europepmc.org/articles/PMC8286840
http://europepmc.org/articles/PMC8286840
Autor:
Dhira Joshi, Lucy R. Marshall, Lucy R. Wedderburn, Stavroula Paraskevopoulou, Steve Gamblin, Georgina H. Cornish, Sonia Gandhi, Charles Swanton, John W. McCauley, William Bolland, Svend Kjaer, Nikhil Faulkner, Hannah Rickman, Rachel Ulferts, Philip Hobson, D.J. Benton, Laura E. McCoy, Ana Agua-Doce, Rupert Beale, Annachiara Rosa, Chloe Roustan, Nicola O’Reilly, Catherine F Houlihan, Christopher Earl, Eleni Nastouli, A.G. Wrobel, Rachael Thompson, Brigitta Stockinger, Kirsty Thomson, Catherine Moore, Bethany R. Jebson, Anna Radziszewska, Coziana Ciurtin, Andrew Riddell, Saira Hussain, Emilie Sanchez, Peter Cherepanov, Elizabeth C. Rosser, Meredyth G. Ll Wilkinson, Kevin W. Ng, Ruth Harvey, Philip A. Walker, Hannah Peckham, Judith Heaney, Gee Yen Shin, Moira J. Spyer, George Kassiotis
Publikováno v:
Science (New York, N.y.)
Science
Science
Antibodies predating infection Immunological memory after infection with seasonal human coronaviruses (hCoVs) may potentially contribute to cross-protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ng et al. report that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b78b2fb2e3b3317126ad45bbfb9684
https://doi.org/10.1126/science.abe1107
https://doi.org/10.1126/science.abe1107
Autor:
Qi Wen Teo, Ho Him Wong, Tiaan Heunis, Viktoriya Stancheva, Asmaa Hachim, Huibin Lv, Lewis YL Siu, Julian Ho, Yun Lan, Chris Ka Pun Mok, Rachel Ulferts, Sumana Sanyal
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71698724557c668c9e45ec9d57a97b6b
https://doi.org/10.2139/ssrn.4144966
https://doi.org/10.2139/ssrn.4144966
Autor:
Lonneke van der Linden, Laia Vives-Adrián, Barbara Selisko, Cristina Ferrer-Orta, Xinran Liu, Kjerstin Lanke, Rachel Ulferts, Armando M De Palma, Federica Tanchis, Nesya Goris, David Lefebvre, Kris De Clercq, Pieter Leyssen, Céline Lacroix, Gerhard Pürstinger, Bruno Coutard, Bruno Canard, David D Boehr, Jamie J Arnold, Craig E Cameron, Nuria Verdaguer, Johan Neyts, Frank J M van Kuppeveld
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004733 (2015)
The genus Enterovirus of the family Picornaviridae contains many important human pathogens (e.g., poliovirus, coxsackievirus, rhinovirus, and enterovirus 71) for which no antiviral drugs are available. The viral RNA-dependent RNA polymerase is an att
Externí odkaz:
https://doaj.org/article/184861f7dc7545d98c08e695d7ff897c
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 4, Pp 100903-(2021)
STAR Protocols, Vol 2, Iss 4, Pp 100903-(2021)
Determining how hematopoietic stem and progenitor cells (HSPCs) can be infected by viruses is necessary to understand and predict how the immune system will drive the host response. We present here a protocol to analyze the capacity of SARS-CoV-2 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c4d6251483cd2b5afc2bf950247683
http://europepmc.org/articles/PMC8492889
http://europepmc.org/articles/PMC8492889