Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Rachel, Gurrell"'
Autor:
Rachel Gurrell, Philip Iredale, Alexis Evrard, Venceslas Duveau, Céline Ruggiero, Corinne Roucard
Publikováno v:
CNS Neuroscience & Therapeutics. 28:1875-1882
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c89bb97140b739a02f258a0090a24c4
https://doi.org/10.1111/cns.13927
https://doi.org/10.1111/cns.13927
Autor:
Jacqueline A. French, Elena Cleary, Dennis Dlugos, Gail Farfel, Kathleen Farrell, Barry Gidal, Caitlin L. Grzeskowiak, Rachel Gurrell, Cynthia Harden, Tracy J. Stalvey, Julia Tsai, Elaine C. Wirrell, David Blum, Nathan Fountain
Publikováno v:
Epilepsia. 63:2664-2670
Drug treatment for children with epilepsy should, ideally, be governed by evidence from adequate and well-controlled clinical studies. However, these studies are difficult to conduct, and so direct evidence supporting the informed use of specific dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459eca2cf7adb51471429476cf52ba5d
https://doi.org/10.1111/epi.17366
https://doi.org/10.1111/epi.17366
Autor:
Rachel Gurrell, Ih Chang, Ann Dandurand, Sridhard Duvvuri, Amy Guigliano, Gina Pastino, Theresa Pham, Stacey Versavel, Gabriel Jacobs, Koshar Safai Pour, Rob Zuiker, Raymond Sanchez, John Renger
Publikováno v:
Sunday, April 23.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::717304e923339ec5e2bee2905b4e768a
https://doi.org/10.1212/wnl.0000000000202097
https://doi.org/10.1212/wnl.0000000000202097
Autor:
Caroline L. Benn, Pinky Dua, Rachel Gurrell, Peter Loudon, Andrew Pike, R. Ian Storer, Ciara Vangjeli
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Gout is the most common form of inflammatory arthritis and is a multifactorial disease typically characterized by hyperuricemia and monosodium urate crystal deposition predominantly in, but not limited to, the joints and the urinary tract. The preval
Externí odkaz:
https://doaj.org/article/74db2acb93c54e4eb7d0dcaff4767766
Autor:
Flora Hui, Christine T. O. Nguyen, Zheng He, Algis J. Vingrys, Rachel Gurrell, Rebecca L. Fish, Bang V. Bui
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
To consider whether imaging retinal vasculature may be used as a marker for cortical vessels, we compared fluorescein angiography flow dynamics before and after pharmacological disruption of blood-neural barriers. Sodium fluorescein (1%, 200 μl/kg)
Externí odkaz:
https://doaj.org/article/f5dcce559f5a4e98a59c82ab4e2dff12
Autor:
Jason Charng, Zheng He, Algis J. Vingrys, Rebecca L. Fish, Rachel Gurrell, Bang V. Bui, Christine T. Nguyen
Publikováno v:
Journal of Ophthalmology, Vol 2016 (2016)
Objective. To examine whether retinal electrophysiology is a useful surrogate marker of drug penetrance into the central nervous system (CNS). Materials and Methods. Brain and retinal electrophysiology were assessed with full-field visually evoked po
Externí odkaz:
https://doaj.org/article/ad3f51101ff548f78ee0b53b493f9543
Autor:
Pieter Okkerse, Guido van Amerongen, Rachel Gurrell, Pinky Dua, Richard P. Butt, Geert Jan Groeneveld, Pieter S. Siebenga, Mark Whitlock, Donal Gorman, Justin L. Hay
Publikováno v:
British Journal of Anaesthesia. 123:e194-e203
Background This study investigated the analgesic effects of two doses (15 and 65 mg) of PF-06372865, a novel α2/α3/α5 gamma-aminobutyric acid A (GABAA) subunit selective partial positive allosteric modulator (PAM), compared with placebo and pregab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab87fb5998c3e34827328c1f096875fc
https://doi.org/10.1016/j.bja.2018.12.006
https://doi.org/10.1016/j.bja.2018.12.006
Autor:
Flora Hui, Christine T O Nguyen, Phillip A Bedggood, Zheng He, Rebecca L Fish, Rachel Gurrell, Algis J Vingrys, Bang V Bui
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111330 (2014)
PURPOSE: We describe a novel approach to analyze fluorescein angiography to investigate fluorescein flow dynamics in the rat posterior retina as well as identify abnormal areas following laser photocoagulation. METHODS: Experiments were undertaken in
Externí odkaz:
https://doaj.org/article/97a51e26c61a4a03a903854c077e6e5a
Publikováno v:
Clinical Pharmacology in Drug Development
Multiple‐dose pharmacokinetics (PK) and safety were investigated in this phase 1 study of PF‐06372865, a positive allosteric modulator of α2/3/5 subunit‐containing γ‐aminobutyric acid A receptors (NCT03351751). In 2 cohorts (7‐8 PF‐0637
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a01b9d10953ce8d42b607b262bc81f0
https://doi.org/10.1002/cpdd.912
https://doi.org/10.1002/cpdd.912
Autor:
Jason Charng, Christine T Nguyen, Zheng He, Trung M Dang, Algis J Vingrys, Rebecca L Fish, Rachel Gurrell, Phil Brain, Bang V Bui
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74172 (2013)
The electroretinogram (ERG, retina) and visual evoked potential (VEP, brain) are widely used in vivo tools assaying the integrity of the visual pathway. Current recordings in preclinical models are conducted under anesthesia, which alters neural phys
Externí odkaz:
https://doaj.org/article/f70612bf2b964012a234017699ddf46b