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Effect of high-dose rifampicin on efavirenz pharmacokinetics: drug–drug interaction randomized trial
Autor:
Daniel, Atwine, Elisabeth, Baudin, Thibaut, Gelé, Winnie, Muyindike, Kenneth, Mworozi, Racheal, Kyohairwe, Keneth, Kananura, Patrick, Orikiriza, Dan, Nyehangane, Deborah, K T Nanjebe, Valérie, Furlan, Céline, Verstuyft, Aurélie, Barrail-Tran, Anne-Marie, Taburet, Maryline, Bonnet, P, Justumus
Publikováno v:
Journal of Antimicrobial Chemotherapy. 75:1250-1258
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Background: High-dose rifampicin is considered to shorten anti-TB treatment duration but its effect on antiretroviral metabolism is unknown. Objectives: To assess the effect of doubling the rifamp
Background: High-dose rifampicin is considered to shorten anti-TB treatment duration but its effect on antiretroviral metabolism is unknown. Objectives: To assess the effect of doubling the rifamp