Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Rachana Patel"'
Autor:
Laura Melado, Barbara Lawrenz, Daniela Nogueira, Araz Raberi, Rachana Patel, Asina Bayram, Ibrahim Elkhatib, Human Fatemi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Consanguineous marriage is defined as marriage between first or second-degree cousins, with high prevalence in many cultures and societies. Descendants from consanguineous unions have an increased risk for genetic diseases. Additionally, in
Externí odkaz:
https://doaj.org/article/e8645930923e4e6e8f4b9bf204cf2ce7
Publikováno v:
Journal of Affective Disorders Reports, Vol 14, Iss , Pp 100672- (2023)
Background: Young pregnant women are at a higher risk of mental disorders globally. Lack of male partner support is a risk factor for psychological distress among adult women during pregnancy. However, little research has been done in India; in parti
Externí odkaz:
https://doaj.org/article/57fb06dbdf52417ca0348aacd2dede0d
Autor:
Enisha Sarin, Sourav Ghosh Dastidar, Nitin Bisht, Devina Bajpayee, Rachana Patel, Tarun Singh Sodha, Aditya Bhandari, Jaya Swarup Mohanty, Surajit Dey, Subodh Chandra, Ritu Agrawal, Prasant Saboth, Harish Kumar
Publikováno v:
Journal of Family Medicine and Primary Care, Vol 11, Iss 6, Pp 2695-2708 (2022)
Background: Digital learning tools have proliferated among healthcare workers in India. Evidence of their effectiveness is however minimal. We sought to examine the impact of the Safe Delivery App (SDA) on knowledge and confidence among frontline hea
Externí odkaz:
https://doaj.org/article/cc1cd7f8220046668827f4552f9d9a99
Autor:
Marisa Nacke, Emma Sandilands, Konstantina Nikolatou, Álvaro Román-Fernández, Susan Mason, Rachana Patel, Sergio Lilla, Tamas Yelland, Laura C. A. Galbraith, Eva C. Freckmann, Lynn McGarry, Jennifer P. Morton, Emma Shanks, Hing Y. Leung, Elke Markert, Shehab Ismail, Sara Zanivan, Karen Blyth, David M. Bryant
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
The signalling pathways underpinning cell growth and invasion use overlapping components, yet how mutually exclusive responses occur is unclear. Here, the authors show that alternate isoforms of the ARF GTPase exchange factor IQSEC1 direct phosphoino
Externí odkaz:
https://doaj.org/article/5313ed90f36c4817a2437ea2428b588c
Autor:
Mark J. Salji, Arnaud Blomme, J. Henry M. Däbritz, Peter Repiscak, Sergio Lilla, Rachana Patel, David Sumpton, Niels J.F. van den Broek, Ronan Daly, Sara Zanivan, Hing Y. Leung
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104056- (2022)
Summary: Castration-resistant prostate cancer (CRPC) is incurable and remains a significant worldwide challenge (Oakes and Papa, 2015). Matched untargeted multi-level omic datasets may reveal biological changes driving CRPC, identifying novel biomark
Externí odkaz:
https://doaj.org/article/3805fc748f104f7ba51eabf9fb2117d5
Autor:
Arnaud Blomme, Coralie Peter, Ernest Mui, Giovanny Rodriguez Blanco, Ning An, Louise M Mason, Lauren E Jamieson, Grace H McGregor, Sergio Lilla, Chara Ntala, Rachana Patel, Marc Thiry, Sonia H Y Kung, Marine Leclercq, Catriona A Ford, Linda K Rushworth, David J McGarry, Susan Mason, Peter Repiscak, Colin Nixon, Mark J Salji, Elke Markert, Gillian M MacKay, Jurre J Kamphorst, Duncan Graham, Karen Faulds, Ladan Fazli, Martin E Gleave, Edward Avezov, Joanne Edwards, Huabing Yin, David Sumpton, Karen Blyth, Pierre Close, Daniel J Murphy, Sara Zanivan, Hing Y Leung
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 3, Pp n/a-n/a (2022)
Abstract Despite the clinical benefit of androgen‐deprivation therapy (ADT), the majority of patients with advanced prostate cancer (PCa) ultimately develop lethal castration‐resistant prostate cancer (CRPC). In this study, we identified thioeste
Externí odkaz:
https://doaj.org/article/0b32d6de175042e18b789240104f3924
Autor:
Arnaud Blomme, Catriona A. Ford, Ernest Mui, Rachana Patel, Chara Ntala, Lauren E. Jamieson, Mélanie Planque, Grace H. McGregor, Paul Peixoto, Eric Hervouet, Colin Nixon, Mark Salji, Luke Gaughan, Elke Markert, Peter Repiscak, David Sumpton, Giovanny Rodriguez Blanco, Sergio Lilla, Jurre J. Kamphorst, Duncan Graham, Karen Faulds, Gillian M. MacKay, Sarah-Maria Fendt, Sara Zanivan, Hing Y. Leung
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Androgen receptor (AR) signalling regulates cellular metabolism in prostate cancer. Here, the authors perform a proteomics and metabolomics characterisation of prostate cancer cells adapted to long-term resistance to AR inhibition and show rewiring o
Externí odkaz:
https://doaj.org/article/2a468699bc1a4fa682a39a1ff7c055bc
Autor:
Alexandra Traister, Rachana Patel, Anita Huang, Sarvatit Patel, Julia Plakhotnik, Jae Eun Lee, Marel Gonzalez Medina, Chris Welsh, Prutha Ruparel, Libo Zhang, Mark Friedberg, Jason Maynes, John Coles
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245808 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0200342.].
Externí odkaz:
https://doaj.org/article/9bfa15a11705449da7106286eb2ad28a
Autor:
Enisha Sarin, Subir K. Kole, Rachana Patel, Ankur Sooden, Sanchit Kharwal, Rashmi Singh, Mirwais Rahimzai, Nigel Livesley
Publikováno v:
BMC Pregnancy and Childbirth, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background While increase in the number of women delivering in health facilities has been rapid, the quality of obstetric and neonatal care continues to be poor in India, contributing to high maternal and neonatal mortality. Methods The USAI
Externí odkaz:
https://doaj.org/article/a1b33ff8cf124ffab113c9dd806d93c0
Autor:
Rachana Patel, Janis Fleming, Ernest Mui, Carolyn Loveridge, Peter Repiscak, Arnaud Blomme, Victoria Harle, Mark Salji, Imran Ahmad, Katy Teo, Freddie C Hamdy, Ann Hedley, Niels van den Broek, Gillian Mackay, Joanne Edwards, Owen J Sansom, Hing Y Leung
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 4, Pp n/a-n/a (2018)
Abstract Metastatic castration‐resistant prostate cancer (mCRPC) is a lethal form of treatment‐resistant prostate cancer and poses significant therapeutic challenges. Deregulated receptor tyrosine kinase (RTK) signalling mediated by loss of tumou
Externí odkaz:
https://doaj.org/article/f68a51d6e42349948384f58cf1f57479