Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rachana Jayaraman"'
Autor:
Thomas G. Graeber, Roger S. Lo, Vineet Bafna, Daniel S. Peeper, Asha S. Multani, P. Nagesh Rao, Paul J. Hergenrother, Kim H. Paraiso, T. Niroshi Senaratne, Stephen E. Motika, Amelia Palermo, Johanna ten Hoeve, Kyle Sheu, Salwan Alhani, Nikolas G. Balanis, Rachana Jayaraman, Gabriel Karin, Eli Pazol, Jesus Salazar, William P. Crosson, Trevor Ridgley, Prashanthi Dharanipragada, Oscar Krijgsman, Gatien Moriceau, Mark H. Goodman, Jens Luebeck, Shirley H. Lomeli, Siavash R. Dehkordi, Arthur Huang, Jenna K. Minami, Kai Song
Focal amplifications (FA) can mediate targeted therapy resistance in cancer. Understanding the structure and dynamics of FAs is critical for designing treatments that overcome plasticity-mediated resistance. We developed a melanoma model of dual MAPK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005496410afa192ef817de39cbb29907
https://doi.org/10.1158/2159-8290.c.6549616.v1
https://doi.org/10.1158/2159-8290.c.6549616.v1
Autor:
Thomas G. Graeber, Roger S. Lo, Vineet Bafna, Daniel S. Peeper, Asha S. Multani, P. Nagesh Rao, Paul J. Hergenrother, Kim H. Paraiso, T. Niroshi Senaratne, Stephen E. Motika, Amelia Palermo, Johanna ten Hoeve, Kyle Sheu, Salwan Alhani, Nikolas G. Balanis, Rachana Jayaraman, Gabriel Karin, Eli Pazol, Jesus Salazar, William P. Crosson, Trevor Ridgley, Prashanthi Dharanipragada, Oscar Krijgsman, Gatien Moriceau, Mark H. Goodman, Jens Luebeck, Shirley H. Lomeli, Siavash R. Dehkordi, Arthur Huang, Jenna K. Minami, Kai Song
Supplementary Table from Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a8c4bd05ca644172e944aa05c3ccc9
https://doi.org/10.1158/2159-8290.22541326
https://doi.org/10.1158/2159-8290.22541326
Autor:
Thomas G. Graeber, Roger S. Lo, Vineet Bafna, Daniel S. Peeper, Asha S. Multani, P. Nagesh Rao, Paul J. Hergenrother, Kim H. Paraiso, T. Niroshi Senaratne, Stephen E. Motika, Amelia Palermo, Johanna ten Hoeve, Kyle Sheu, Salwan Alhani, Nikolas G. Balanis, Rachana Jayaraman, Gabriel Karin, Eli Pazol, Jesus Salazar, William P. Crosson, Trevor Ridgley, Prashanthi Dharanipragada, Oscar Krijgsman, Gatien Moriceau, Mark H. Goodman, Jens Luebeck, Shirley H. Lomeli, Siavash R. Dehkordi, Arthur Huang, Jenna K. Minami, Kai Song
Supplementary Figure from Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ca04ff69af6e06a7f3fc1472e95733
https://doi.org/10.1158/2159-8290.22541341
https://doi.org/10.1158/2159-8290.22541341
Autor:
Kai Song, Jenna K. Minami, Arthur Huang, Siavash R. Dehkordi, Shirley H. Lomeli, Jens Luebeck, Mark H. Goodman, Gatien Moriceau, Oscar Krijgsman, Prashanthi Dharanipragada, Trevor Ridgley, William P. Crosson, Jesus Salazar, Eli Pazol, Gabriel Karin, Rachana Jayaraman, Nikolas G. Balanis, Salwan Alhani, Kyle Sheu, Johanna ten Hoeve, Amelia Palermo, Stephen E. Motika, T. Niroshi Senaratne, Kim H. Paraiso, Paul J. Hergenrother, P. Nagesh Rao, Asha S. Multani, Daniel S. Peeper, Vineet Bafna, Roger S. Lo, Thomas G. Graeber
Publikováno v:
Cancer Discov
Focal amplifications (FA) can mediate targeted therapy resistance in cancer. Understanding the structure and dynamics of FAs is critical for designing treatments that overcome plasticity-mediated resistance. We developed a melanoma model of dual MAPK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b1c2deee167fc1c89bd6e41a7bb0cd
https://doi.org/10.1158/2159-8290.cd-20-0936
https://doi.org/10.1158/2159-8290.cd-20-0936
Autor:
Jesus Salazar, Senaratne Niroshi, Kim H. T. Paraiso, Kai Song, Trevor Ridgley, Rao Nagesh, William P. Crosson, Jenna Minami, Arthur Huang, Eli Pazol, Rachana Jayaraman, Thomas G. Graeber
Publikováno v:
Cancer Research. 81:2036-2036
Cancer cells display two modes of focal amplifications (FA): extrachromosomal double minutes (DMs/ecDNAs) and intrachromosomal homogenously staining regions (HSRs). Understanding the plasticity of these two modes is critical for preventing targeted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9868afbf9e6682b41ac975165a3118e0
https://doi.org/10.1158/1538-7445.am2021-2036
https://doi.org/10.1158/1538-7445.am2021-2036