Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rachael Vaubel"'
Publikováno v:
Neuro-Oncology. 24:vii287-vii287
Genetic variation can be considered a driver of somatic evolution in glioblastoma (GBM); however, the tumor microenvironment (TME) is a key contributor to the selection process and evolutionary potential of cancer cells. Although diverse ecosystems e
Autor:
Jorge Trejo-Lopez, Thomas Kollmeyer, Corinne Praska, Aditya Raghunathan, Caterina Giannini, Rachael Vaubel, Aivi Nguyen, Mark Jentoft, Kliment Donev, Gang Zheng, Margaret DiGuardo, Benjamin Kipp, Robert Jenkins, Cristiane Ida
Publikováno v:
Neuro-Oncology. 24:vii152-vii152
Diffuse hemispheric glioma, H3 G34-mutant (DHG_H3G34) is a novel tumor type in the 2021 WHO CNS classification. We describe a comprehensive sequencing and high-resolution genome-wide copy number analysis of a series of cases clinically tested by a si
Autor:
Rachael Vaubel, Rahul Kumar, Taylor Weiskittel, Sarah Jenkins, Surendra Dasari, Joon Uhm, Daniel Honore Lachance, Paul Brown, Jamie Van Gompel, Benjamin Kipp, William Sukov, Caterina Giannini, Derek Johnson, Aditya Raghunathan
Publikováno v:
Neuro-Oncology. 24:vii158-vii158
Atypical meningiomas (CNS WHO grade 2) show an intermediate risk of recurrence/progression, and molecular parameters informing management following gross total resection (GTR) remain to be established. We performed comprehensive genomic analysis in 6
Autor:
Frederick Varn, Gordon Ye, Padmaja Ghospurkar, Taylor Wade, Mustafa Khasraw, Eric S Lipp, Beth Hermes, Carol Elliott, Joseph F Costello, Chibo Hong, Pim French, Wies Vallentgoed, Marta Padovan, Ho-Keung Ng, Kay Li, Hui Gan, Kerryn Westcott, Rachael Vaubel, Craig Horbinski, Kathleen McCortney, Sun Ha Paek, Hyo-Eun Moon, Peter LaViolette, Allison Lowman, Jill Barnholtz-Sloan, Pieter Wesseling, Roel Verhaak
Publikováno v:
Neuro-Oncology. 24:vii152-vii152
Oligodendroglioma is a subtype of diffuse glioma defined by a mutation in the isocitrate dehydrogenase (IDH) genes and a co-deletion of chromosome arms 1p and 19q. These tumors primarily occur in adult patients in their third and fourth decade of lif
Autor:
Nazanin Ijad, Katie L Waller, Naema Nayyar, Juliana M Larson, Joshua Spear, Daniel Cahill, Frederick G Barker, Evanthia Galanis, Jann Sarkaria, Hiroaki Wakimoto, Rachael Vaubel, Priscilla Brastianos
Publikováno v:
Neuro-Oncology. 24:vii230-vii230
BACKGROUND Adequate treatment options are limited for patients with meningiomas once they have exhausted surgery and radiation. As our molecular understanding of meningiomas and their progression has improved, CDK, FAK, and RAF/MEK pathways have emer
Autor:
Danielle M. Burgenske, Ann C. Mladek, Shulan Tian, Mark A. Schroeder, Zeng Hu, Brett L. Carlson, Paul A. Decker, Jeanette E. Eckel-Passow, Rachael Vaubel, Jann N. Sarkaria
Publikováno v:
Cancer Research. 82:4001-4001
The Mayo Clinic collection of patient-derived xenograft (PDXs) has been developed from the direct implantation of glioblastoma (GBM) samples into immunodeficient mice. Over 105 models have been extensively characterized with regards to histology, inv