Telomere attrition rates are associated with weather conditions and predict productive lifespan in dairy cattle

Autor: Luise A. Seeker, Sarah L. Underwood, Rachael V. Wilbourn, Jennifer Dorrens, Hannah Froy, Rebecca Holland, Joanna J. Ilska, Androniki Psifidi, Ainsley Bagnall, Bruce Whitelaw, Mike Coffey, Georgios Banos, Daniel H. Nussey

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract Telomere length is predictive of adult health and survival across vertebrate species. However, we currently do not know whether such associations result from among-individual differences in telomere length determined genetically or by early-

Externí odkaz: https://doaj.org/article/ab6c6709e3b64eb4a9068e831fb649dc

Heritable variation in telomere length predicts mortality in Soay sheep

Autor: Hannah Froy, Kathryn A. Watt, Lea Harrington, Jill G. Pilkington, Daniel H. Nussey, Rachael V. Wilbourn, Josephine M. Pemberton, Luise A. Seeker, Sarah L. Underwood, Jennifer Dorrens

Publikováno v: Proc Natl Acad Sci U S A
Froy, H, Underwood, S, Dorrens, J, Seeker, L, Watt, K, Wilbourn, R, Pilkington, J, Harrington, L, Pemberton, J M & Nussey, D H 2021, ' Heritable variation in telomere length predicts mortality in soay sheep ', Proceedings of the National Academy of Sciences, vol. 118, no. 15, e2020563118 . https://doi.org/10.1073/pnas.2020563118

Telomere length (TL) is considered an important biomarker of whole-organism health and ageing. Across humans and other vertebrates, short telomeres are associated with increased subsequent mortality risk, but the processes responsible for this correl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54aa9e49da01bbe9f466e81f53b4a99c
https://pubmed.ncbi.nlm.nih.gov/33876756

Short-term telomere dynamics is associated with glucocorticoid levels in wild populations of roe deer

Autor: Jean-Michel Gaillard, Maryline Pellerin, Corinne Régis, Benjamin Rey, Jeanne Duhayer, Hannah Froy, Emmanuelle Gilot-Fromont, Jeffrey Carbillet, Rachael V. Wilbourn, Louise Cheynel, Jean-François Lemaître, Sylvia Pardonnet, Hélène Verheyden, François Débias, Daniel H. Nussey, Sarah L. Underwood, Rupert Palme, A. J. Mark Hewison

Publikováno v: Comparative Biochemistry and Physiology-A: Comparative Physiology
Comparative Biochemistry and Physiology-A: Comparative Physiology, Elsevier, 2021, 252, pp.1-7. ⟨10.1016/j.cbpa.2020.110836⟩
Comparative Biochemistry and Physiology
Comparative Biochemistry and Physiology, Elsevier, 2021, 252, ⟨10.1016/j.cbpa.2020.110836⟩
Comparative Biochemistry and Physiology-A: Comparative Physiology, 2021, 252, pp.1-7. ⟨10.1016/j.cbpa.2020.110836⟩
Comparative Biochemistry and Physiology-Part A: Molecular and Integrative Physiology
Comparative Biochemistry and Physiology-Part A: Molecular and Integrative Physiology, Elsevier, 2021, 252, pp.110836. ⟨10.1016/j.cbpa.2020.110836⟩
Lemaître, J-F, Carbillet, J, Rey, B, Palme, R, Froy, H, Wilbourn, R V, Underwood, S L, Cheynel, L, Gaillard, J-M, Hewison, A J M, Verheyden, H, Débias, F, Duhayer, J, Régis, C, Pardonnet, S, Pellerin, M, Nussey, D H & Gilot-Fromont, E 2021, ' Short-term telomere dynamics is associated with glucocorticoid levels in wild populations of roe deer ', Comparative Biochemistry and Physiology-Part A: Molecular & Integrative Physiology, vol. 252, 110836 . https://doi.org/10.1016/j.cbpa.2020.110836

International audience; While evidence that telomere length is associated with health and mortality in humans and birds is accumulating, a large body of research is currently seeking to identify factors that modulate telomere dynamics. We tested the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2d8858c3e22bb876822cf5fba1ec3a
https://hal.archives-ouvertes.fr/hal-03060315

Life-long telomere attrition predicts health and lifespan in a large mammal

Autor: Mike Coffey, Luise A. Seeker, Androniki Psifidi, Joanna J. Ilska, Rebecca Holland, Daniel H. Nussey, Georgios Banos, Sarah L. Underwood, Ainsley Bagnall, Jennifer Fairlie, Rachael V. Wilbourn, Bruce Whitelaw, Hannah Froy

Telomere length measured in blood cells is predictive of subsequent adult health and survival across a range of vertebrate species. However, we currently do not know whether such associations result from among-individual differences in telomere lengt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d9ed31179dd7739dd95da1d13d8bfca
https://doi.org/10.1101/2020.06.22.165563

Bovine telomere dynamics and the association between telomere length and productive lifespan

Autor: Androniki Psifidi, Rebecca Holland, Daniel H. Nussey, Jennifer Fairlie, Rachael V. Wilbourn, Ainsley Bagnall, Luise A. Seeker, Sarah L. Underwood, Joanna J. Ilska, Hannah Froy, Mike Coffey, Eliane Salvo-Chirnside, Georgios Banos, Bruce Whitelaw

Publikováno v: Seeker, L, Warner, J, Psifidi, A, Wilbourn, R, Underwood, S, Fairlie, J, Holland, R, Froy, H, Salvo-Chirnside, E, Bagnall, A, Whitelaw, C, Coffey, M, Nussey, D & Banos, G 2018, ' Bovine telomere dynamics and the association between telomere length and productive lifespan ', Scientific Reports, vol. 8, no. 1, 12748 . https://doi.org/10.1038/s41598-018-31185-z
Scientific Reports (Nature)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)

Average telomere length (TL) in blood cells has been shown to decline with age in a range of vertebrate species, and there is evidence that TL is a heritable trait associated with late-life health and mortality in humans. In non-human mammals, few st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe425a1de9690314af393b9b7505e94d
https://doi.org/10.1038/s41598-018-31185-z