Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Rachael S. Preston"'
Autor:
Elite Possik, Yann Nouët, Marie-Claude Gingras, Fanny Dupuy, Ming Yan, Andrew R. Tee, Barry J. Coull, Sylvie Sabourin, Dmitri Kharitidi, Laëtitia Chotard, Rachael S. Preston, Russell G. Jones, Anders Bondo Dydensborg, Maurice A.M. van Steensel, Elaine A. Dunlop, Miriam A.F. Kamps, David Mark Davies, Taren Roughead, Arnim Pause, Brandon Faubert, Zahra Jalali
Publikováno v:
Journal of Clinical Investigation, 124(6), 2640-2650. American Society for Clinical Investigation
The Warburg effect is a tumorigenic metabolic adaptation process characterized by augmented aerobic glycolysis, which enhances cellular bioenergetics. In normal cells, energy homeostasis is controlled by AMPK; however, its role in cancer is not under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f60b0e59cd5a5ce8ac080dda890f72
https://doi.org/10.1172/JCI71749
https://doi.org/10.1172/JCI71749
Autor:
Tjinta Brinkhuizen, Arnim Pause, Rachael S. Preston, Andrew R. Tee, David Mark Davies, Elaine A. Dunlop, Anders Bondo Dydensborg, M.A.M. van Steensel, Stephen C. Land, Lieke Gijezen, Fred H. Menko, K. T. Harper, Andrew Philp, Keith Baar, Tijs Claessens
Publikováno v:
Oncogene, 30(10), 1159-1173. Nature Publishing Group
Preston, R S, Philp, A, Claessens, T, Gijezen, L, Dydensborg, A B, Dunlop, E A, Harper, K T, Brinkhuizen, T, Menko, F H, Davies, D M, Land, S C, Pause, A, Baar, K, van Steensel, M A M & Tee, A R 2011, ' Absence of the Birt-Hogg-Dube gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility ', Oncogene, vol. 30, no. 10, pp. 1159-1173 . https://doi.org/10.1038/onc.2010.497
Preston, R S, Philp, A, Claessens, T, Gijezen, L, Dydensborg, A B, Dunlop, E A, Harper, K T, Brinkhuizen, T, Menko, F H, Davies, D M, Land, S C, Pause, A, Baar, K, van Steensel, M A M & Tee, A R 2011, ' Absence of the Birt-Hogg-Dube gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility ', Oncogene, vol. 30, no. 10, pp. 1159-1173 . https://doi.org/10.1038/onc.2010.497
Under conditions of reduced tissue oxygenation, hypoxia-inducible factor (HIF) controls many processes, including angiogenesis and cellular metabolism, and also influences cell proliferation and survival decisions. HIF is centrally involved in tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d787e3e5f0995aaedf4ee6b1d6c89a
https://hdl.handle.net/1871/36585
https://hdl.handle.net/1871/36585