Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rachael R. Schulte"'
Autor:
Rachael R. Schulte, Leena Choi, Nipun Utreja, Sara L. Van Driest, C. Michael Stein, Richard H. Ho
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 343-353 (2021)
High‐dose (HD) methotrexate (MTX) is a critical component of treatment for hematologic malignancies in children and young adults. Therapeutic drug monitoring is necessary due to substantial interindividual variation in MTX clearance. Common functio
Externí odkaz:
https://doaj.org/article/c73797cf452840839d080118e03119f7
Autor:
Ashley Hinson, Rachael R. Schulte, Van Huynh, Michael J. Burke, Jennifer L. McNeer, Etan Orgel, Erin H. Breese, Joanna Pierro, Benjamin A. Mixon, Seth J. Rotz
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 10, Iss 21, Pp 7551-7560 (2021)
Cancer Medicine, Vol 10, Iss 21, Pp 7551-7560 (2021)
Background Pegaspargase (PEG‐ASP) is an integral component of therapy for acute lymphoblastic leukemia (ALL) but is associated with hepatotoxicity that may delay or limit future therapy. Obese and adolescent and young adult (AYA) patients are at hi
Autor:
Muayad Alali, Karl Balsara, Alka Khaitan, Drew A. Streicher, Kathryn L. Barros, Hailey C. Budnick, Rachael R. Schulte
Publikováno v:
Pediatric Blood & Cancer. 70
Autor:
Rachael R. Schulte, Sara L. Van Driest, C. Michael Stein, Leena Choi, Richard H. Ho, Nipun Utreja
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 1, Pp 343-353 (2021)
Clinical and Translational Science, Vol 14, Iss 1, Pp 343-353 (2021)
High‐dose (HD) methotrexate (MTX) is a critical component of treatment for hematologic malignancies in children and young adults. Therapeutic drug monitoring is necessary due to substantial interindividual variation in MTX clearance. Common functio
Autor:
Adam S. DuVall, Rachael R. Schulte, Jessica Hochberg, Jennifer L. McNeer, Archie Bleyer, Allyson Flower, Manasi Vivek Madiwale, Michael J. Burke
Publikováno v:
Leuk Lymphoma
Asparaginase, an important treatment component for acute lymphoblastic leukemia (ALL), causes severe hepatotoxicity in some patients. Levocarnitine is a mitochondrial co-factor that can potentially ameliorate the mitochondrial toxicity of asparaginas
Autor:
Richard H. Ho, Rachael R. Schulte
Publikováno v:
Mol Pharmacol
The organic anion transporting polypeptides (OATPs) are a superfamily of drug transporters involved in the uptake and disposition of a wide array of structurally divergent endogenous and exogenous substrates, including steroid hormones, bile acids, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1f50d368cefb7eec57f33039e0787b
https://europepmc.org/articles/PMC6442320/
https://europepmc.org/articles/PMC6442320/
Publikováno v:
Cancer Letters. 304:137-143
In ovarian cancer, the molecular targeted chemotherapeutics could increase the efficiency of low-dose radiotherapy while decreasing injury to adjusted organs. In irradiated A2780 human ovarian carcinoma cells, cytosolic phospholipase A2 (cPLA(2)) inh
Autor:
Richard H. Ho, Rachael R. Schulte
Publikováno v:
Journal of Clinical Oncology. 36:e22503-e22503
e22503Background: High-dose methotrexate (HD MTX) is a critical treatment component for pediatric acute lymphoblastic leukemia (ALL), non-Hodgkin lymphoma, and osteosarcoma. While very effective, H...
Autor:
Lori C. Jordan, Robert P. Naftel, John C. Wellons, Anna Morad, Rachael R. Schulte, Robert F. Sidonio
Publikováno v:
Pediatric neurology. 50(6)
Background Newborns are at risk for vitamin K deficiency and subsequent bleeding unless supplemented at birth. Vitamin K deficiency bleeding is an acquired coagulopathy in newborn infants because of accumulation of inactive vitamin K-dependent coagul
Autor:
James Andrews, Mark Armstrong, Jinghua Feng, Kai Yu, Courtney D. DiNardo, Sarah L King-Smith, Andreas W. Schreiber, Keyur P. Patel, Luca Malcovati, Claire C. Homan, Hana Raslova, Michael W. Drazer, Jeffery M. Klco, Elvira Deolinda Rodrigues Pereira Velloso, Lucy A. Godley, Carolyn Owen, Benedict Yan, Mineo Kurokawa, Claude Preudhomme, Jude Fitzgibbon, Mario Cazzola, Julia Dobbins, Stefan Fröhling, Neil V. Morgan, Kiran Tawana, Csaba Bödör, Rémi Favier, Georges Natsoulis, Joanne Lee, Alan B. Cantor, Paul P. Liu, Erin Degelman, Peer Arts, David Lawrence, Anna L. Brown, Hugh Y. Rienhoff, Hamish S. Scott, Nicolas Duployez, Thuong Ha, Rachael R. Schulte, Christopher N. Hahn, Tim Ripperger, Alwin Krämer
Publikováno v:
Haematologica