Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rachael M. Cunningham"'
Autor:
Rachel M. P. Caddiell, Rachael M. Cunningham, Philip A. White, B. Duncan X. Lascelles, Margaret E. Gruen
Publikováno v:
Frontiers in Pain Research, Vol 4 (2023)
BackgroundVeterinarians hold distinct breed-specific pain sensitivity beliefs that differ from the general public but are highly consistent with one another. This is remarkable as there is no current scientific evidence for biological differences in
Externí odkaz:
https://doaj.org/article/f04a6b1e2e384135b0d94fbe8197b87c
Autor:
B. Duncan X. Lascelles, Rachel M Park, David Knazovicky, Margaret E. Gruen, Rachael M Cunningham
Publikováno v:
Journal of Visualized Experiments.
Quantitative sensory testing (QST) is used to evaluate the function of the somatosensory system in dogs by assessing the response to applied mechanical and thermal stimuli. QST is used to determine normal dogs' sensory thresholds and evaluate alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5d344e449bee8760d7fb2b708e3839
https://doi.org/10.3791/62841
https://doi.org/10.3791/62841
Autor:
Min Chieh Yang, Emily C. Sutton, Victoria J. DeRose, Jack Y Prochnau, Christine E. McDevitt, Matthew V. Yglesias, Christopher H. Hendon, Austin M. Mroz, Rachael M. Cunningham
Publikováno v:
J Am Chem Soc
Platinum(II) compounds are a critical class of chemotherapeutic agents. Recent studies have highlighted the ability of a subset of Pt(II) compounds, including oxaliplatin but not cisplatin, to induce cytotoxicity via nucleolar stress rather than a ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1999d388410a9b3a6dad4c58a08f5e26
https://doi.org/10.1021/jacs.9b10319
https://doi.org/10.1021/jacs.9b10319
Publikováno v:
J Inorg Biochem
Identifying the interactions of small molecules with biomolecules in complex cellular environments is a significant challenge. As one important example, despite being widely used for decades, much is still not understood regarding the cellular target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24e4e50c7b437742c8379c574f45a80
https://doi.org/10.1016/j.jinorgbio.2018.09.007
https://doi.org/10.1016/j.jinorgbio.2018.09.007
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::795151c117ab764280880b01ebbf0961
https://doi.org/10.1096/fasebj.2019.33.1_supplement.471.17
https://doi.org/10.1096/fasebj.2019.33.1_supplement.471.17
Publikováno v:
ACS chemical biology. 12(11)
Pt(II)-based anticancer drugs are widely used in the treatment of a variety of cancers, but their clinical efficacy is hindered by undesirable side effects and resistance. While much research has focused on Pt(II) drug interactions with DNA, there is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10bbe3ff0770d6ad00aa3d9c1b3837d
https://pubmed.ncbi.nlm.nih.gov/28892625
https://pubmed.ncbi.nlm.nih.gov/28892625
Autor:
Michael M. Haley, Victoria J. DeRose, Jonathan D. White, Andrea N. Loes, Alan D. Moghaddam, Rachael M. Cunningham
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 44(8)
cis-[Pt(2-azido-1,3-propanediamine)Cl2] is a reagent for high-yield post-treatment fluorescent labelling of Pt(II) biomolecular targets using click chemistry and exhibits a bias in conformational isomers in the context of duplex DNA. Pt–protein add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5a9b4fe3324987ebe7851d6f2ab894
https://pubmed.ncbi.nlm.nih.gov/25338004
https://pubmed.ncbi.nlm.nih.gov/25338004