Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rachael Lawrance"'
Autor:
Nathan A. Clarke, Brendon Wong, Rachael Lawrance, Anders Ingelgård, Ingolf Griebsch, David Cella, Andrew Trigg
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract Background Breast cancer is one of the most common cancers in women. Patient-reported outcome measures are used to evaluate patients’ health-related quality of life in clinical breast cancer studies. This study evaluated the structure, val
Externí odkaz:
https://doaj.org/article/c8c133fb5818480080b343a7b39677fb
Autor:
Rachael Lawrance, Evgeny Degtyarev, Philip Griffiths, Peter Trask, Helen Lau, Denise D’Alessio, Ingolf Griebsch, Gudrun Wallenstein, Kim Cocks, Kaspar Rufibach
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 4, Iss 1, Pp 1-8 (2020)
Abstract Background Published in 2019, a new addendum to the ICH E9 guideline presents the estimand framework as a systematic approach to ensure alignment among clinical trial objectives, trial execution/conduct, statistical analyses, and interpretat
Externí odkaz:
https://doaj.org/article/3b5822f5bed34085bce0c320c49936e6
Autor:
Delphine Réa, Carla Boquimpani, Michael J. Mauro, Yosuke Minami, Alex Allepuz, Vikalp Kumar Maheshwari, Denise D’Alessio, Ying Wu, Rachael Lawrance, Sarunas Narbutas, Giora Sharf, Andreas Hochhaus
Publikováno v:
Leukemia. 37:1060-1067
In ASCEMBL, an open-label, randomized Phase 3 study, asciminib demonstrated superior efficacy and better safety profile compared with bosutinib in patients with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with ≥2 tyrosine
Autor:
Martin Reck, Tudor-Eliade Ciuleanu, Manuel Cobo, Michael Schenker, Bogdan Zurawski, Juliana Menezes, Eduardo Richardet, Jaafar Bennouna, Enriqueta Felip, Oscar Juan-Vidal, Aurelia Alexandru, Ying Cheng, Hiroshi Sakai, Luis Paz-Ares, Shun Lu, Thomas John, Xiaowu Sun, Aniela Moisei, Fiona Taylor, Rachael Lawrance, Xiaoqing Zhang, Judi Sylvester, Yong Yuan, Steven I. Blum, John R. Penrod, David P. Carbone
Publikováno v:
European Journal of Cancer. 183:174-187
Autor:
Arnaud Scherpereel, Scott Antonia, Yolanda Bautista, Francesco Grossi, Dariusz Kowalski, Gérard Zalcman, Anna K. Nowak, Nobukazu Fujimoto, Solange Peters, Anne S. Tsao, Aaron S. Mansfield, Sanjay Popat, Xiaowu Sun, Rachael Lawrance, Xiaoqing Zhang, Melinda J. Daumont, Bryan Bennett, Mike McKenna, Paul Baas
Publikováno v:
Lung Cancer, 167, 8-16. ELSEVIER IRELAND LTD
Objective: In CheckMate 743 (NCT02899299), nivolumab + ipilimumab significantly prolonged overall survival in patients with unresectable malignant pleural mesothelioma (MPM). We present patient-reported outcomes (PROs). Materials and Methods: Patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6db15a71fb123abecc807eb485cd80
https://hdl.handle.net/1887/3565034
https://hdl.handle.net/1887/3565034
Autor:
John A. Bridgewater, Ian Chau, Joseph Gricar, Steven I. Blum, Fiona Taylor, Rachael Lawrance, Brad Padilla, Christine Yip, Lucjan Wyrwicz
Publikováno v:
Journal of Clinical Oncology. 40:262-262
262 Background: This analysis evaluated HRQoL as exploratory endpoints in CheckMate 648, a randomized, open-label, global Phase 3 study, evaluating treatment with N+I, N+CT and CT alone in inoperable advanced, recurrent, or metastatic ESCC. Methods:
Autor:
X. Sun, Prianka Singh, A. Moreno-Koehler, Fiona Taylor, Rachael Lawrance, A. Leso, Steven I. Blum, B. Padilla
Publikováno v:
Value in Health. 24:S34-S35
Autor:
Gudrun Wallenstein, Kaspar Rufibach, Ingolf Griebsch, Evgeny Degtyarev, Philip Griffiths, Denise D'Alessio, Peter Trask, Helen Lau, Rachael Lawrance, Kim Cocks
Publikováno v:
Journal of Patient-Reported Outcomes
Journal of Patient-Reported Outcomes, Vol 4, Iss 1, Pp 1-8 (2020)
Journal of Patient-Reported Outcomes, Vol 4, Iss 1, Pp 1-8 (2020)
BackgroundPublished in 2019, a new addendum to the ICH E9 guideline presents the estimand framework as a systematic approach to ensure alignment among clinical trial objectives, trial execution/conduct, statistical analyses, and interpretation of res
Autor:
Grant D. Stewart, Giovanni Zanotti, Chloe Johnson, Danielle Bargo, Elaine Brohan, Rachael Lawrance, Sarah Bentley, Michael Staehler, Elizabeth Exall, Bryan Bennett
Publikováno v:
Patient education and counseling. 104(1)
Objectives This study developed, and established the content validity, of a conversation aid tool (CAT) for use in clinical practice with renal cell carcinoma (RCC) patients who receive a curative nephrectomy and are at high-risk of recurrence. The C
Autor:
Rachael Lawrance, Mouna Akacha, Anna Berglind, David Wright, Oliver N. Keene, Alexander Schacht, Stephen J. Ruberg
Publikováno v:
Pharmaceutical statisticsREFERENCES. 19(4)
In drug development, we ask ourselves which population, endpoint and treatment comparison should be investigated. In this context, we also debate what matters most to the different stakeholders that are involved in clinical drug development, for exam