Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Rachael L Sumner"'
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008414 (2021)
Neuroplasticity is essential to learning and memory in the brain; it has therefore also been implicated in numerous neurological and psychiatric disorders, making measuring the state of neuroplasticity of foremost importance to clinical neuroscience.
Externí odkaz:
https://doaj.org/article/1f5c88b70fe44adeb0e6bbcf175ff8e3
Autor:
Alexander D Shaw, Suresh D Muthukumaraswamy, Neeraj Saxena, Rachael L Sumner, Natalie E Adams, Rosalyn J Moran, Krish D Singh
Publikováno v:
NeuroImage, Vol 221, Iss , Pp 117189- (2020)
Cortical recordings of task-induced oscillations following subanaesthetic ketamine administration demonstrate alterations in amplitude, including increases at high-frequencies (gamma) and reductions at low frequencies (theta, alpha). To investigate t
Externí odkaz:
https://doaj.org/article/acb3b55db3c64cb18b8d1ef0af97b169
Publikováno v:
BMC Neuroscience, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Microdosing psychedelics is a phenomenon with claimed cognitive benefits that are relatively untested clinically. Pre-clinically, psychedelics have demonstrated enhancing effects on neuroplasticity, which cannot be measured direct
Externí odkaz:
https://doaj.org/article/34a36cd186c64521aa7dc2d435256889
Autor:
Rachael L. Sumner, Rebecca L. McMillan, Anna Forsyth, Suresh D. Muthukumaraswamy, Alexander D. Shaw
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Revealing the acute cortical pharmacodynamics of an antidepressant dose of ketamine in humans with depression is key to determining the specific mechanism(s) of action for alleviating symptoms. While the downstream effects are characterised
Externí odkaz:
https://doaj.org/article/86ed6ed44aac4b74abd3b1643c45a0ac
Autor:
Claire J. Cadwallader, Jennifer Steiniger, Patrick S. Cooper, Shou-Han Zhou, Joshua Hendrikse, Rachael L. Sumner, Ian J. Kirk, Trevor T.-J. Chong, James P. Coxon
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Long-term potentiation (LTP) is a form of neuroplasticity commonly implicated in mechanistic models of learning and memory. Acute exercise can boost LTP in the motor cortex, and is associated with a shift in excitation/inhibition (E:I) balan
Externí odkaz:
https://doaj.org/article/9b326f279bcf4175b2a245c2ae257125
Autor:
Julia R. Plank, Stephanie C. Glover, Ben D. Moloney, Nicholas R. Hoeh, Frederick Sundram, Rachael L. Sumner, Suresh Muthukumaraswamy, Joanne C. Lin
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Major depressive disorder (MDD) is a leading cause of disability worldwide. The current treatments are ineffective in approximately one-third of patients, resulting in a large economic burden and reduced quality of life for a sign
Externí odkaz:
https://doaj.org/article/2e1c9e4d86f64eed9fc56b3fc5593ae7
Autor:
Elizabeth Stone, Malak Alshakhouri, Alexander Shaw, Suresh Muthukumaraswamy, Rachael L. Sumner
Publikováno v:
Neuroendocrinology.
Introduction: The combined oral contraceptive pill (COC) is often employed to address physical and neurological symptoms in menstrual cycle-related disorders by suppressing shifts in endogenous gonadal hormone fluctuations. Symptom persistence, espec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb4fbb18020a0eef009b0bf747ff92f3
https://doi.org/10.1159/000530805
https://doi.org/10.1159/000530805
Publikováno v:
Australian & New Zealand Journal of Psychiatry. 56:1378-1383
With the extensive public, commercial and scientific interest from what has been widely termed the psychedelic renaissance, it is important that the scientific practices and results obtained from its implementation into medicine are put under a criti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf36840ad7b72fab6461e51f46631b20
https://doi.org/10.1177/00048674221081763
https://doi.org/10.1177/00048674221081763
Autor:
Joseph C. C. Chen, Rachael L. Sumner, Venkat Krishnamurthy Naga, Nicholas Hoeh, Hafis Adetokunbo Ayeni, Vikrant Singh, Andrew Wilson, Douglas Campbell, Frederick Sundram, Suresh D. Muthukumaraswamy
Publikováno v:
The Journal of Clinical Psychiatry. 83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c038a2b8fee63a11bf32225e0ecad420
https://doi.org/10.4088/jcp.21m14310
https://doi.org/10.4088/jcp.21m14310
Autor:
Rachael L. Sumner, Rebecca McMillan, James Chen, Christie Anderson, Meg J. Spriggs, Frederick Sundram, Amelia French, Akshaya Rajan, SungHun Jung, Gemma Malpas, Rhys Ponton, Suresh D. Muthukumaraswamy, John Hay, Emme Chacko
Publikováno v:
Journal of Psychopharmacology. 35:946-961
Background: Ketamine is central to one of the most rapidly growing areas of neuroscientific research into novel treatments for depression. Limited research has indicated that the psychedelic properties of ketamine may play a role in its antidepressan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762a095475eca9f6b77f457cb61d1ea9
https://doi.org/10.1177/0269881121998321
https://doi.org/10.1177/0269881121998321