Zobrazeno 1 - 10
of 8 327
pro vyhledávání: '"Rachael L"'
Uptake of health economic evaluations alongside clinical trials in Australia: an observational study
Autor:
Alayna Carrandi, Cynthia Wells, Rachael L. Morton, Richard Norman, Helen Skouteris, Amy Grove, Alisa M. Higgins
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Australia’s clinical trials sector is highly productive with continued sector investment needed to enhance research impact. Generating economic evidence alongside trials has the potential to facilitate the implementation of tria
Externí odkaz:
https://doaj.org/article/bd4a50fd36874b7495fe50011357b6f8
Autor:
R. Kijoon Kim, Natalie L. Truby, Gabriella M. Silva, Joseph A. Picone, Cary S. Miller, Amber N. Baldwin, Rachael L. Neve, Xiaohong Cui, Peter J. Hamilton
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Prior research has identified differential protein expression levels of linker histone H1x within the ventral hippocampus (vHipp) of stress-susceptible versus stress-resilient mice. These mice are behaviorally classified based on their diver
Externí odkaz:
https://doaj.org/article/fc42d15a544e4b7c95a78a31e8a4a12a
Autor:
Claire Snyder, Rebecca Mercieca-Bebber, Claudia Rutherford, Kim Sutherland, Melissa Tinsley, Olalekan Lee Aiyegbusi, Jessica Nikolovski, Rachael L. Morton, Matilda Armstrong, Gill Hartas, Brad Rossiter, Margaret Fagan, Rubina Amin-Korim
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Introduction Patient-reported outcome measures (PROMs) are validated and standardised questionnaires that capture patients’ own reports of their symptoms, functioning and well-being. PROMs can facilitate communication between patients and clinician
Externí odkaz:
https://doaj.org/article/3820a02f9222485a837b872a8df42575
Autor:
Doah Cho, Sarah J. Lord, Robyn Ward, Maarten IJzerman, Andrew Mitchell, David M. Thomas, Saskia Cheyne, Andrew Martin, Rachael L. Morton, John Simes, Chee Khoon Lee
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Advances in targeted therapy development and tumor sequencing technology are reclassifying cancers into smaller biomarker-defined diseases. Randomized controlled trials (RCTs) are often impractical in rare diseases, leading to calls for s
Externí odkaz:
https://doaj.org/article/01054442bb48485e8ed565d3f77224e0
Autor:
Alina L. Capatina, Jodie R. Malcolm, Jack Stenning, Rachael L. Moore, Katherine S. Bridge, William J. Brackenbury, Andrew N. Holding
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The events that control breast cancer progression and metastasis are complex and intertwined. Hypoxia plays a key role both in oncogenic transformation and in fueling the metastatic potential of breast cancer cells. Here we review the impact of hypox
Externí odkaz:
https://doaj.org/article/f6a8d132a2184bfd98fff60b790f10b2
Publikováno v:
BMC Neuroscience, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Microdosing psychedelics is a phenomenon with claimed cognitive benefits that are relatively untested clinically. Pre-clinically, psychedelics have demonstrated enhancing effects on neuroplasticity, which cannot be measured direct
Externí odkaz:
https://doaj.org/article/34a36cd186c64521aa7dc2d435256889
Autor:
Rachael L. Sumner, Rebecca L. McMillan, Anna Forsyth, Suresh D. Muthukumaraswamy, Alexander D. Shaw
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Revealing the acute cortical pharmacodynamics of an antidepressant dose of ketamine in humans with depression is key to determining the specific mechanism(s) of action for alleviating symptoms. While the downstream effects are characterised
Externí odkaz:
https://doaj.org/article/86ed6ed44aac4b74abd3b1643c45a0ac
Autor:
Natalie L. Truby, R. Kijoon Kim, Gabriella M. Silva, Xufeng Qu, Joseph A. Picone, Rebecca Alemu, Claire N. Atiyeh, Rachael L. Neve, Jinze Liu, Xiaohong Cui, Peter J. Hamilton
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The neurobiological origins of social behaviors are incompletely understood. Here we utilized synthetic biology approaches to reprogram the function of ZFP189, a transcription factor whose expression and function in rodent prefrontal cortex
Externí odkaz:
https://doaj.org/article/1234686ad85e4efcb9cd6f5e378b07ad
Autor:
Ali Al‐Rikaby, Ahmad Sulaiman, Jake R. Thompson, Robyn P. M. Saw, Frances Boyle, Nicole Taylor, Matteo S. Carlino, Rachael L. Morton, Omgo E. Nieweg, John F. Thompson, Iris Bartula
Publikováno v:
Cancer Medicine, Vol 12, Iss 23, Pp 21373-21388 (2023)
Abstract Introduction The COVID‐19 pandemic caused rapid implementation of telehealth for melanoma follow‐up care in Australia. This study explores Australian melanoma patients and clinicians' level of satisfaction with telehealth. Methods A cros
Externí odkaz:
https://doaj.org/article/bd7eabcf48414daab330a8b547ad8cbd
Autor:
Leif I. Solberg, Jeanette Y. Ziegenfuss, Rachael L. Rivard, Christine K. Norton, Robin R. Whitebird, Glyn Elwyn, Mark Swiontkowski
Publikováno v:
Journal of Patient-Centered Research and Reviews, Vol 10, Iss 4, Pp 210-218 (2023)
Purpose: The study aim was to test the feasibility of collecting qualitative patient-preferred outcomes or goals and the degree of their attainment as an addition to a standardized process for collecting quantitative composite patient-reported outcom
Externí odkaz:
https://doaj.org/article/200fb7d526dc40eb8bf4e4e5ec9c99c1