Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rachael K. Parkin"'
Autor:
Matthew L. Freedman, Shiv Srivastava, David G. McLeod, Muneesh Tewari, Philip W. Kantoff, William K. Oh, Steve Lee, Paula Herman, Michelle Dyke, Daniel W. Lin, Rachael K. Parkin, Brian R. Fritz, Kristin G. Ardlie, Jennifer A. Chan, Meir J. Stampfer, Kathryn L. Penney, Lorelei Mucci, Fredrick R. Schumacher, Dorota J. Hawksworth, Yongmei Chen, Gyorgy Petrovics, Stacia K. Wyman, Meredith M. Regan, Christine A. Beckwith, Mark M. Pomerantz
Polymorphisms at 8q24 are robustly associated with prostate cancer risk. The risk variants are located in nonprotein coding regions and their mechanism has not been fully elucidated. To further dissect the function of this locus, we tested two hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b526bacb48c60e766e02d821563825dd
https://doi.org/10.1158/0008-5472.c.6499109.v1
https://doi.org/10.1158/0008-5472.c.6499109.v1
Autor:
Matthew L. Freedman, Shiv Srivastava, David G. McLeod, Muneesh Tewari, Philip W. Kantoff, William K. Oh, Steve Lee, Paula Herman, Michelle Dyke, Daniel W. Lin, Rachael K. Parkin, Brian R. Fritz, Kristin G. Ardlie, Jennifer A. Chan, Meir J. Stampfer, Kathryn L. Penney, Lorelei Mucci, Fredrick R. Schumacher, Dorota J. Hawksworth, Yongmei Chen, Gyorgy Petrovics, Stacia K. Wyman, Meredith M. Regan, Christine A. Beckwith, Mark M. Pomerantz
Supplementary Figure 1 from Evaluation of the 8q24 Prostate Cancer Risk Locus and MYC Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d5a4bfcc97612ba47e0f48cccf5b19
https://doi.org/10.1158/0008-5472.22379042
https://doi.org/10.1158/0008-5472.22379042
Autor:
David Myerson, Rachael K. Parkin
Publikováno v:
Virchows Archiv. 474:365-374
Reconstitution of hepatocytes by hematopoietic stem cells-a phenomenon which occurs in rodents under highly selective conditions-results from infrequent fusion between incoming myelomonocytes and host hepatocytes, with subsequent proliferation. Human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095e99b48a53a46957c36ce83fe8fac0
https://doi.org/10.1007/s00428-018-2497-8
https://doi.org/10.1007/s00428-018-2497-8
Autor:
Stacia K Wyman, Rachael K Parkin, Patrick S Mitchell, Brian R Fritz, Kathy O'Briant, Andrew K Godwin, Nicole Urban, Charles W Drescher, Beatrice S Knudsen, Muneesh Tewari
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5311 (2009)
MicroRNAs (miRNAs) are small regulatory RNAs that are implicated in cancer pathogenesis and have recently shown promise as blood-based biomarkers for cancer detection. Epithelial ovarian cancer is a deadly disease for which improved outcomes could be
Externí odkaz:
https://doaj.org/article/98a21526e4ff4b96950296d02042e2b9
Autor:
Charles W. Drescher, Kavita Garg, Robert C Gentleman, Emily C. Knouf, Deepayan Sarkar, Yesenia Correa, Elizabeth M. Swisher, Rachael K. Parkin, Nicole Urban, Kathy O'Briant, Andrew K. Godwin, Kaitlyn Wurz, Walter L. Ruzzo, Jason D. Arroyo, Muneesh Tewari
Publikováno v:
Nucleic Acids Research
Although microRNAs (miRNAs) are important regulators of gene expression, the transcriptional regulation of miRNAs themselves is not well understood. We employed an integrative computational pipeline to dissect the transcription factors (TFs) responsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c714485d2d935ece227ea7da75abbc
https://doi.org/10.1093/nar/gkr731
https://doi.org/10.1093/nar/gkr731
Autor:
Rachael K. Parkin, Stacia K. Wyman, Michael Krouse, Lucas Dennis, Philippa J. Webster, Brian R. Fritz, Muneesh Tewari, Emily C. Knouf, Daniel W. Lin
Publikováno v:
Genome Research. 21:1450-1461
Modification of microRNA sequences by the 3′ addition of nucleotides to generate so-called “isomiRs” adds to the complexity of miRNA function, with recent reports showing that 3′ modifications can influence miRNA stability and efficiency of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a932abc11d9d04555bf64862e7297050
https://doi.org/10.1101/gr.118059.110
https://doi.org/10.1101/gr.118059.110
Publikováno v:
Methods. 50:298-301
MicroRNAs (miRNAs) are small (approximately 22 nt) RNAs that play important roles in gene regulatory networks by binding to and repressing the activity of specific target mRNAs. Recent studies have indicated that miRNAs circulate in a stable, cell-fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a21c28b4f532e2f020104fc1bd52c74
https://doi.org/10.1016/j.ymeth.2010.01.032
https://doi.org/10.1016/j.ymeth.2010.01.032
Autor:
Emily C. Knouf, Ausra Bendoraite, Beatrice S. Knudsen, Beth Y. Karlan, Nicole Urban, Muneesh Tewari, Andrew K. Godwin, Charles W. Drescher, Kavita Garg, Rachael K. Parkin, Kathy O'Briant, Aviva P. Ventura, Evan M. Kroh
Publikováno v:
Gynecologic Oncology. 116:117-125
Objective Our objective was to characterize the expression and function of the miR-200 family of microRNAs (miRNA) in ovarian carcinogenesis. Methods We used qRT-PCR to examine expression of the miR-200 miRNA family and its predicted targets, the ZEB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa05ba22c96ef2b821dae773591efd2
https://doi.org/10.1016/j.ygyno.2009.08.009
https://doi.org/10.1016/j.ygyno.2009.08.009
Autor:
Kristin G. Ardlie, Philip W. Kantoff, Jennifer A. Chan, Yongmei Chen, Fredrick R. Schumacher, Meir J. Stampfer, Gyorgy Petrovics, Shiv Srivastava, David G. McLeod, Daniel W. Lin, Lorelei A. Mucci, Christine A. Beckwith, Meredith M. Regan, Matthew L. Freedman, Dorota Hawksworth, Steve Lee, Stacia K. Wyman, Rachael K. Parkin, Mark Pomerantz, Muneesh Tewari, Paula Herman, Michelle L. Dyke, Kathryn L. Penney, William Oh, Brian R. Fritz
Publikováno v:
Cancer Research. 69:5568-5574
Polymorphisms at 8q24 are robustly associated with prostate cancer risk. The risk variants are located in nonprotein coding regions and their mechanism has not been fully elucidated. To further dissect the function of this locus, we tested two hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a18ceb7f6ff99c7d2e4e5b441c741c
https://doi.org/10.1158/0008-5472.can-09-0387
https://doi.org/10.1158/0008-5472.can-09-0387
Autor:
Peter S. Nelson, Patrick S. Mitchell, Stacia K. Wyman, Charles W. Drescher, Amelia Peterson, Rachael K. Parkin, April Allen, Robert L. Vessella, Daniel W. Lin, Kathy O'Briant, Muneesh Tewari, Daniel Martin, Evan M. Kroh, Robert Gentleman, Brian R. Fritz, Era L. Pogosova-Agadjanyan, Beatrice S. Knudsen, Nicole Urban, Derek L. Stirewalt, Jennifer Noteboom
Publikováno v:
Proceedings of the National Academy of Sciences. 105:10513-10518
Improved approaches for the detection of common epithelial malignancies are urgently needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs (miRNAs) are small (≈22 nt) regulatory RNAs that are frequently dysregulated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4c1fe702bb051f88872409eeca276f
https://doi.org/10.1073/pnas.0804549105
https://doi.org/10.1073/pnas.0804549105