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pro vyhledávání: '"Rachael Garlish"'
Autor:
Mark D. Carr, Mariusz Muzylak, David McMillan, Richard J. Franklin, Vaclav Veverka, Daniel Christopher Brookings, Joanne E. Compson, Kelly Le Riche, Laura Ellen Newnham, Carl Brendan Doyle, Thomas A Ceska, Rachael Garlish, James Petrie Turner, Jiye Shi, Bernadette Sweeney, Alistair James Henry, Patrick M. Slocombe, Jeffery Kennedy, Gill Holdsworth, Martyn K. Robinson
Publikováno v:
The Journal of biological chemistry. 287(32)
LRP5 and LRP6 are proteins predicted to contain four six-bladed β-propeller domains and both bind the bone-specific Wnt signaling antagonist sclerostin. Here, we report the crystal structure of the amino-terminal region of LRP6 and using NMR show th