Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rachael Fay"'
Autor:
Daniel F. Earley, Amaury Guillou, Simon Klingler, Rachael Fay, Melanie Gut, Faustine d’Orchymont, Shamisa Behmaneshfar, Linus Reichert, Jason P. Holland
Publikováno v:
JACS Au, Vol 2, Iss 3, Pp 646-664 (2022)
Externí odkaz:
https://doaj.org/article/33351dd3157747ecaf4e4c64f6038143
Autor:
Jennifer Lamb, Faustine d'Orchymont, Rachael Fay, Florian Gribi, Jose Esteban Flores, Melanie Gut, Simon Klingler, Patricia Pires, Jan Bühler, Shamisa Behmaneshfar, Amaury Guillou, Daniel F. Earley, Jason P. Holland
Publikováno v:
CHIMIA, Vol 74, Iss 12, Pp 946-952 (2020)
The synthesis, characterisation and application of radiolabelled compounds for use in diagnostic and therapeutic medicine requires a diverse skill set. This article highlights a selection of our ongoing projects that aim to provide new synthetic meth
Externí odkaz:
https://doaj.org/article/5d95a102eb33480c8a8fd891fd2c6f10
Autor:
Rachael Fay, Imre Törő, Anna-Lena Schinke, Branko Simic, Jonas V. Schaefer, Birgit Dreier, Andreas Plückthun, Jason P. Holland
Publikováno v:
Molecular Pharmaceutics. 19:3576-3585
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87c6ac7b2d5443c225020fe4623bbe4d
https://doi.org/10.1021/acs.molpharmaceut.2c00136
https://doi.org/10.1021/acs.molpharmaceut.2c00136
Autor:
Isabella Attinger-Toller, Rachael Fay, Romain Bertrand, Philipp Probst, Ramona Stark, Roger Santimaria, Dragan Grabulovski, Bernd Schlereth, Philipp Rene Spycher
Publikováno v:
Cancer Research. 83:LB219-LB219
The Araris’ site-specific and one-step linker conjugation technology aims at generating stable, safe and highly potent ADCs without the need for antibody engineering prior to payload conjugation. Here, we generated an anti-HER2 ADC using a Topoisom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79a5acd6320576771332e567d7691844
https://doi.org/10.1158/1538-7445.am2023-lb219
https://doi.org/10.1158/1538-7445.am2023-lb219
Autor:
Bernd Schlereth, Isabella Attinger-toller, Philipp Probst, Romain Bertrand, Ramona Stark, Roger Santimaria, Emma Renard, Rachael Fay, Jeff P. Sharman, Dragan Grabulovski, Philipp Spycher
Publikováno v:
Blood. 140:11568-11569
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::324df3f888a6441ed9d901fab1e857bd
https://doi.org/10.1182/blood-2022-160056
https://doi.org/10.1182/blood-2022-160056
Publikováno v:
Journal of Nuclear Medicine. 61:1072-1078
Methods that provide rapid access to radiolabeled antibodies are vital in the development of diagnostic and radiotherapeutic agents for PET or radioimmunotherapy. The human hepatocyte growth factor receptor (c-MET) signaling pathway is dysregulated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca19a3988fe8747bf3ec251e66386be9
https://doi.org/10.2967/jnumed.119.237180
https://doi.org/10.2967/jnumed.119.237180
Autor:
Daniel F, Earley, Amaury, Guillou, Simon, Klingler, Rachael, Fay, Melanie, Gut, Faustine, d'Orchymont, Shamisa, Behmaneshfar, Linus, Reichert, Jason P, Holland
Publikováno v:
JACS Au. 2(3)
The creation of discrete, covalent bonds between a protein and a functional molecule like a drug, fluorophore, or radiolabeled complex is essential for making state-of-the-art tools that find applications in basic science and clinical medicine. Photo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0b0f1cbde0e68ba770e4bdc057bf822
https://pubmed.ncbi.nlm.nih.gov/35373206
https://pubmed.ncbi.nlm.nih.gov/35373206
Autor:
Amaury, Guillou, Daniel F, Earley, Simon, Klingler, Eda, Nisli, Laura J, Nüesch, Rachael, Fay, Jason P, Holland
Publikováno v:
Bioconjugate chemistry. 32(7)
Most experimental work in the space of bioconjugation chemistry focuses on using new methods to construct covalent bonds between a cargo molecule and a protein of interest such as a monoclonal antibody (mAb). Bond formation is important for generatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca4c478db7397c538a46b9be346c6cdc
https://pubmed.ncbi.nlm.nih.gov/34056896
https://pubmed.ncbi.nlm.nih.gov/34056896
Autor:
Isabella Attinger-Toller, Philipp Probst, Romain Bertrand, Ramona Stark, Roger Santimaria, Emma Renard, Rachael Fay, Dragan Grabulovski, Bernd Schlereth, Philipp René Spycher
Publikováno v:
Cancer Research. 82:2910-2910
The Araris’ site-specific and 1-step linker conjugation technology aims at generating safe and highly potent ADCs without the need for antibody engineering prior to linker-payload conjugation. We developed a very stable anti-CD79b-MMAE ADC with thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5ec27257963a9fc90c70ac7ee75daf2
https://doi.org/10.1158/1538-7445.am2022-2910
https://doi.org/10.1158/1538-7445.am2022-2910
Autor:
Daniel Earley, Amaury Guillou, Simon Klingler, Rachael Fay, Melanie Gut, Faustine d’Orchymont, Shamisa Behmaneshfar, Linus Reichert, Jason Holland
Publikováno v:
Nuclear Medicine and Biology. :S114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd2cb821250d20bb00ad6f916e0dd852
https://doi.org/10.1016/s0969-8051(22)00254-2
https://doi.org/10.1016/s0969-8051(22)00254-2