Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rachael E Rayner"'
Autor:
Audra R Fullen, Jessica L Gutierrez-Ferman, Rachael E Rayner, Sun Hee Kim, Phylip Chen, Purnima Dubey, Daniel J Wozniak, Mark E Peeples, Estelle Cormet-Boyaka, Rajendar Deora
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011193 (2023)
Traditionally, whooping cough or pertussis caused by the obligate human pathogen Bordetella pertussis (Bp) is described as an acute disease with severe symptoms. However, many individuals who contract pertussis are either asymptomatic or show very mi
Externí odkaz:
https://doaj.org/article/bc2b3fce391b44ec8c3bbcd114a6c8b1
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121870 (2015)
BackgroundGlobally, over 800 000 children under five die each year from infectious diseases caused by Streptococcus pneumoniae. To understand genetic relatedness between isolates, study transmission routes, assess the impact of human interventions e.
Externí odkaz:
https://doaj.org/article/68971d5702ee4e0cb3bd1f36393649e2
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-14 (2022)
Abstract Background Acute exposure to cigarette smoke alters gene expression in several biological pathways such as apoptosis, immune response, tumorigenesis and stress response, among others. However, the effects of electronic nicotine delivery syst
Externí odkaz:
https://doaj.org/article/e76cbcc83b4f429099ee6e9af87d8ec0
Autor:
MuChun Tsai, Rachael E. Rayner, Lexie Chafin, Daniela Farkas, Jessica Adair, Chelsea Mishan, Rama K. Mallampalli, Sun Hee Kim, Estelle Cormet-Boyaka, James D. Londino
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L666-L676
Respiratory viruses, such as influenza, decrease airway cilia function and expression, which leads to reduced mucociliary clearance and inhibited overall immune defense. Ubiquitination is a posttranslational modification using E3 ligases, which plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1207f84c88cec78e5812e087d6fe383
https://doi.org/10.1152/ajplung.00191.2022
https://doi.org/10.1152/ajplung.00191.2022
Autor:
Patrudu S. Makena, Rachael E. Rayner, G.L. Prasad, Jack Wellmerling, Estelle Cormet-Boyaka, Jing Zhao
Publikováno v:
Cell Biochemistry and Biophysics. 80:217-228
Cigarette smoke deregulates several biological pathways by modulating gene expression in airway epithelial cells and altering the physiology of the airway epithelium. The effects of repeated exposures of electronic cigarette delivery systems (ENDS) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f484df79fc6c667d3c1d0ec52f894d7e
https://doi.org/10.1007/s12013-021-01042-4
https://doi.org/10.1007/s12013-021-01042-4
Autor:
Mostafa M. Eltobgy, Ashley Zani, Adam D. Kenney, Shady Estfanous, Eunsoo Kim, Asmaa Badr, Cierra Carafice, Kylene Daily, Owen Whitham, Maciej Pietrzak, Amy Webb, Jeffrey Kawahara, Adrian C. Eddy, Parker Denz, Mijia Lu, Mahesh KC, Mark E. Peeples, Jianrong Li, Jian Zhu, Jianwen Que, Richard Robinson, Oscar Rosas Mejia, Rachael E. Rayner, Luanne Hall-Stoodley, Stephanie Seveau, Mikhail A. Gavrilin, Xiaoli Zhang, Jeronay Thomas, Jacob E. Kohlmeier, Mehul S. Suthar, Eugene Oltz, Andrea Tedeschi, Frank H. Robledo-Avila, Santiago Partida-Sanchez, Emily A. Hemann, Eman Abdelrazik, Adriana Forero, Shahid M. Nimjee, Prosper N. Boyaka, Estelle Cormet-Boyaka, Jacob S. Yount, Amal O. Amer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(21)
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) is a worldwide health concern, and new treatment strategies are needed. Targeting inflammatory innate immunity pathways holds therapeutic promise, but effective molecular targets remain e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d41407d3800934f9acfc60d7cf1ba2d
https://pubmed.ncbi.nlm.nih.gov/35588457
https://pubmed.ncbi.nlm.nih.gov/35588457
Autor:
Jack Wellmerling, Rachael E. Rayner, Sheng‐Wei Chang, Elizabeth L. Kairis, Sun Hee Kim, Amit Sharma, Prosper N. Boyaka, Estelle Cormet‐Boyaka
Publikováno v:
FASEB J
Mutations in the CFTR gene lead to cystic fibrosis, a genetic disease associated with chronic infection and inflammation and ultimately respiratory failure. The most common CF-causing mutation is F508del and CFTR modulators (correctors and potentiato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd8ee0dd2eeb1070a44d3215fb288c1
https://pubmed.ncbi.nlm.nih.gov/35412656
https://pubmed.ncbi.nlm.nih.gov/35412656
Autor:
Emily Hemann, Mark E. Peeples, Eman Abdelrazik, Estelle Cormet-Boyaka, Asmaa Badr, Prosper N. Boyaka, Maciej Pietrzak, Shady Estfanous, Jeffrey Kawahara, Ashley Zani, Krishnan Mahesh, Adam D. Kenney, Jianrong Li, Oscar Rosas Mejia, Mostafa Eltobgy, Owen Whitham, Shahid M Nimjee, Richard T. Robinson, Andrea Tedeschi, Santiago Partida-Sanchez, Parker J. Denz, Frank Roberto, Adrian Eddy, Jacob S. Yount, Amy Webb, Cierra Carafice, Rachael E. Rayner, Eunsoo Kim, Mikhail A. Gavrilin, Kylene Daily, Jian Zhu, Amal O. Amer, Jianwen Que, Luanne Hall-Stoodley, Adriana Forero, Mijia Lu, Stephanie Seveau
SARS-CoV-2 is a worldwide health concern, and new treatment strategies are needed 1. Targeting inflammatory innate immunity pathways holds therapeutic promise, but effective molecular targets remain elusive. Here, we show that human caspase-4 (CASP4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af96809a1af3397cecceec5bce8d10b8
https://doi.org/10.1101/2021.09.24.461743
https://doi.org/10.1101/2021.09.24.461743
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 320(2)
Cigarette smoking is a risk factor for several lung diseases, including chronic obstructive pulmonary disease, cardiovascular disease, and lung cancer. The potential health effects of chronic use of electronic nicotine delivery systems (ENDS) is uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265f07c08e7af3a365ee53d75b678660
https://pubmed.ncbi.nlm.nih.gov/33207918
https://pubmed.ncbi.nlm.nih.gov/33207918
Autor:
Scott W. Lallier, Susan D. Reynolds, Guy Brock, Estelle Cormet-Boyaka, Cynthia L Hill, Mahelet Tadesse, Rachael E. Rayner, Hemant K. Parekh, Alfahdah Alsudayri, Don Hayes
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 20(1)
Background The conducting airway epithelium is repaired by tissue specific stem cells (TSC). In response to mild/moderate injury, each TSC repairs a discrete area of the epithelium. In contrast, severe epithelial injury stimulates TSC migration and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb89b6cb075093bcbc29378345f51c4
https://pubmed.ncbi.nlm.nih.gov/33187933
https://pubmed.ncbi.nlm.nih.gov/33187933