Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rachael Cusack"'
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Acute respiratory distress syndrome (ARDS) is a severe organ failure occurring mainly in critically ill patients as a result of different types of insults such as sepsis, trauma or aspiration. Sepsis is the main cause of ARDS, and it contributes to a
Externí odkaz:
https://doaj.org/article/fd03a032eefe42599dce16c7f75813d0
Publikováno v:
Antibiotics, Vol 13, Iss 2, p 162 (2024)
Sepsis stands as a formidable global health challenge, with persistently elevated mortality rates in recent decades. Each year, sepsis not only contributes to heightened morbidity but also imposes substantial healthcare costs on survivors. This narra
Externí odkaz:
https://doaj.org/article/10ffdcdc51ab40548e26c9ade2118d19
Autor:
Gustavo Sganzerla Martinez, Ali Toloue Ostadgavahi, Abdullah Mahmud Al-Rafat, Alexis Garduno, Rachael Cusack, Jesus Francisco Bermejo-Martin, Ignacio Martin-Loeches, David Kelvin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMillions of deaths worldwide are a result of sepsis (viral and bacterial) and septic shock syndromes which originate from microbial infections and cause a dysregulated host immune response. These diseases share both clinical and immunolog
Externí odkaz:
https://doaj.org/article/1fedf63953ed4ca6afdf8965b9662321
Autor:
Gustavo Martinez, Alexis Garduno, Abdullah Mahmud-Al-Rafat, Ali Toloue Ostadgavahi, Ann Avery, Scheila de Avila e Silva, Rachael Cusack, Cheryl Cameron, Mark Cameron, Ignacio Martin-Loeches, David Kelvin
Publikováno v:
PeerJ, Vol 10, p e14487 (2022)
Background The severe form of COVID-19 can cause a dysregulated host immune syndrome that might lead patients to death. To understand the underlying immune mechanisms that contribute to COVID-19 disease we have examined 28 different biomarkers in two
Externí odkaz:
https://doaj.org/article/7ee1c7f188f64fecb9559416bf5e4d62
Publikováno v:
Microorganisms, Vol 11, Iss 5, p 1119 (2023)
It is evident that the admission of some patients with sepsis and septic shock to hospitals is occurring late in their illness, which has contributed to the increase in poor outcomes and high fatalities worldwide across age groups. The current diagno
Externí odkaz:
https://doaj.org/article/729fc1851cfe40f38d7506e7617ba0ea
Autor:
Alexis Garduno, Gustavo Sganzerla Martinez, Ali Toloue Ostadgavahi, David Kelvin, Rachael Cusack, Ignacio Martin-Loeches
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 778 (2023)
Critically ill COVID-19 patients start developing single respiratory organ failure that often evolves into multiorgan failure. Understanding the immune mechanisms in severe forms of an infectious disease (either critical COVID-19 or bacterial septic
Externí odkaz:
https://doaj.org/article/85312269d4254be5850092563299924b
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3150 (2022)
Endothelial integrity maintains microcirculatory flow and tissue oxygen delivery. The endothelial glycocalyx is involved in cell signalling, coagulation and inflammation. Our ability to treat critically ill and septic patients effectively is determin
Externí odkaz:
https://doaj.org/article/5e3a5c292b814b52b82bd34c6def7826
Publikováno v:
Expert Opinion on Investigational Drugs. 31:173-192
Ventilator-associated pneumonia (VAP) is common; its prevalence has been highlighted by the Covid-19 pandemic. Even young patients can suffer severe nosocomial infection and prolonged mechanical ventilation. Multidrug-resistant bacteria can spread al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020f5f1d9a29820e0b0b489d3d7ea81d
https://doi.org/10.1080/13543784.2022.2030312
https://doi.org/10.1080/13543784.2022.2030312
Publikováno v:
Journal of clinical medicine. 11(24)
Sepsis is one of the most common and deadly syndromes faced in Intensive Care settings globally. Recent advances in bedside imaging have defined the changes in the microcirculation in sepsis. One of the most advocated interventions for sepsis is flui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb11e727b55e19a93afc9793ab9cc69
https://pubmed.ncbi.nlm.nih.gov/36555895
https://pubmed.ncbi.nlm.nih.gov/36555895
Publikováno v:
Irish journal of medical science. 189(3)
BackgroundHip fracture is a growing healthcare challenge, with 6–8% 30-day mortality and 20–30% of patients incurring major morbidity, including impaired mobilisation and ability to live independently. While observational studies have shown no be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f91f26f59b1876d7c9648e5933c7db
https://pubmed.ncbi.nlm.nih.gov/33215266
https://pubmed.ncbi.nlm.nih.gov/33215266