Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rachael Bartlett"'
Autor:
Lianna W Wat, Charlotte Chao, Rachael Bartlett, Justin L Buchanan, Jason W Millington, Hui Ju Chih, Zahid S Chowdhury, Puja Biswas, Vivian Huang, Leah J Shin, Lin Chuan Wang, Marie-Pierre L Gauthier, Maria C Barone, Kristi L Montooth, Michael A Welte, Elizabeth J Rideout
Publikováno v:
PLoS Biology, Vol 18, Iss 1, p e3000595 (2020)
Triglycerides are the major form of stored fat in all animals. One important determinant of whole-body fat storage is whether an animal is male or female. Here, we use Drosophila, an established model for studies on triglyceride metabolism, to gain i
Externí odkaz:
https://doaj.org/article/efc2d880de93438aa7b85fc01f716bd6
Publikováno v:
PeerJ, Vol 5, p e3064 (2017)
Background Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disease characterised by the accumulation of aggregated proteins, microglia activation and motor neuron loss. The mechanisms underlying neurodegeneration and di
Externí odkaz:
https://doaj.org/article/e9d1a627cefa4c099ef1a7a299248308
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 5, Pp 749-750 (2017)
Externí odkaz:
https://doaj.org/article/f2dd4e6ad8ea4a16ab721e8461e4d186
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
The P2X7 purinergic receptor is a ligand-gated cation channel expressed on leukocytes including microglia. This study aimed to determine if P2X7 activation induces the uptake of organic cations, reactive oxygen species (ROS) formation, and death in t
Externí odkaz:
https://doaj.org/article/98c97882bc8843fe996931556621e080
Publikováno v:
Purinergic Signalling. 18:451-467
Mutant superoxide dismutase 1 (SOD1) can be constitutively released from motor neurons and transmitted to naïve motor neurons to promote the progression of amyotrophic lateral sclerosis (ALS). However, the biological impacts of this process and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22a4d70f99171c893e381b7f5acb3ac
https://doi.org/10.1007/s11302-022-09863-5
https://doi.org/10.1007/s11302-022-09863-5
Autor:
Natalie Matosin, Janine Arloth, Darina Czamara, Katrina Z. Edmond, Malosree Maitra, Anna Sophie Fröhlich, Silvia Martinelli, Dominic Kaul, Rachael Bartlett, Amber R. Curry, Nils C. Gassen, Kathrin Hafner, Nikola S Müller, Karolina Worf, Ghalia Rehawi, Corina Nagy, Thorhildur Halldorsdottir, Cristiana Cruceanu, Miriam Gagliardi, Nathalie Gerstner, Maik Ködel, Vanessa Murek, Michael J Ziller, Elizabeth Scarr, Ran Tao, Andrew E. Jaffe, Thomas Arzberger, Peter Falkai, Joel E. Kleinmann, Daniel R. Weinberger, Naguib Mechawar, Andrea Schmitt, Brian Dean, Gustavo Turecki, Thomas M. Hyde, Elisabeth B. Binder
Identification and characterisation of novel targets for treatment is a priority in the field of psychiatry.FKBP5is a gene with decades of evidence suggesting its pathogenic role in a subset of psychiatric patients, with potential to be leveraged as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90df05b67e6f42174d7c4ade5b831fb6
https://doi.org/10.1101/2021.01.27.428487
https://doi.org/10.1101/2021.01.27.428487
Autor:
Leanne Stokes, Belinda L. Curtis, Shikara Keshiya, Tracey Berg, Reece A. Sophocleous, Stephen J Curtis, Ronald Sluyter, Rocio K. Finol-Urdaneta, Aine Seavers, Mark Dowton, Vanessa Sluyter, Rachael Bartlett, Lachlan Bell, Lezanne Ooi
Publikováno v:
Br J Pharmacol
Background and purpose P2X4 receptors are emerging therapeutic targets for treating chronic pain and cardiovascular disease. Dogs are well-recognised natural models of human disease, but information regarding P2X4 receptors in dogs is lacking. To aid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740e9b239fac14416e1f97b2ef876423
https://europepmc.org/articles/PMC7236074/
https://europepmc.org/articles/PMC7236074/
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 36:736-744
The current study aimed to determine if probenecid could directly impair the canine P2X7 receptor, a ligand-gated cation channel activated by extracellular adenosine 5′-triphosphate (ATP). Patch clamp measurements demonstrated that probenecid impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f78c090e38813c938224a759fdc23c
https://doi.org/10.1080/15257770.2017.1391395
https://doi.org/10.1080/15257770.2017.1391395
Autor:
Sibylle G. Schwab, Rachael Bartlett, Natalie Matosin, Zoltán Sarnyai, Shakeh Momartin, Lezanne Ooi
Publikováno v:
Psychiatry Research. 296:113661
Displacement of people from their homes, families and countries is a current global crisis, with over 70 million people forcibly on the move. A substantial proportion of these people will end up in regions with a different language and culture, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88659f3665fa7f25eb19bc772d428d3
https://doi.org/10.1016/j.psychres.2020.113661
https://doi.org/10.1016/j.psychres.2020.113661
Autor:
Charlotte Chao, Puja Biswas, Leah J Shin, Zahid Sadek Chowdhury, Hui Ju Chih, Maria Cecilia Barone, Marie-Pierre L Gauthier, Justin L Buchanan, Vivian Huang, Rachael Bartlett, Kristi L. Montooth, Jason W Millington, Lianna W Wat, Lin Chuan Wang, Michael A. Welte, Elizabeth J. Rideout
Publikováno v:
PLoS Biology, Vol 18, Iss 1, p e3000595 (2020)
PLoS Biology
PLoS Biology
Triglycerides are the major form of stored fat in all animals. One important determinant of whole-body fat storage is whether an animal is male or female. Here, we use Drosophila, an established model for studies on triglyceride metabolism, to gain i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8105eda269d04f596bda63f13f0a2625
https://doi.org/10.1371/journal.pbio.3000595
https://doi.org/10.1371/journal.pbio.3000595