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Autor:
Shaday Michan, Adam B. Stein, Hanjia Guo, Surinder Kumar, Mary E. Skinner, Rachael Baliirra, Costas A. Lyssiotis, Sharlene M. Day, David A. Sinclair, David B. Lombard
Publikováno v:
Circulation Research. 129
Heart failure (HF) is defined as an inability of the heart to pump blood sufficiently to meet the metabolic demands of the body. HF with systolic dysfunction is caused by a progressive decline in contractile function and chronic hemodynamic overload,