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pro vyhledávání: '"Rachael Arthur"'
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 1, Iss 3, Pp 131-152 (2020)
Chronic lymphocytic leukemia is a common form of leukemia and is dependent on growth-promoting signaling via the B-cell receptor. The Bruton tyrosine kinase (BTK) is an important mediator of B-cell receptor signaling and the irreversible BTK inhibito
Externí odkaz:
https://doaj.org/article/729f332306704bf79581d1fd2c30b09b
Autor:
Rachael Arthur, Alexander Wathen, Elizabeth A. Lemm, Freda K. Stevenson, Francesco Forconi, Adam J. Linley, Andrew J. Steele, Graham Packham, Beatriz Valle-Argos
Publikováno v:
Cellular signalling. 96
BTK inhibitors (BTKi) have dramatically improved outcomes for patients with chronic lymphocytic leukaemia (CLL) and some forms of B-cell lymphoma. However, new strategies are needed to enhance responses. Here we have performed a detailed analysis of
Autor:
Paul Skipp, Erika Parkinson, Richard Cubberley, Rachael Arthur, Sergio Regufe da Mota, Maja Aleksic
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 62
The potential risk of skin sensitisation, associated with the development of allergic contact dermatitis (ACD), is a consideration in the safety assessment of new ingredients for use in personal care products. Protein haptenation in skin by sensitisi