Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rachael, McCloy"'
Autor:
Kamila A. Marzec, Samuel Rogers, Rachael McCloy, Benjamin L. Parker, David E. James, D. Neil Watkins, Andrew Burgess
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Microtubule-associated serine/threonine kinase-like (MASTL) has emerged as a critical regulator of mitosis and as a potential oncogene in a variety of cancer types. To date, Arpp-19/ENSA are the only known substrates of MASTL. However, with
Externí odkaz:
https://doaj.org/article/3331cc1a3f214642bc1ecc88d07abe93
Autor:
Jennifer Lim, Alexander Murphy, Stephen Wong, Adnan Nagrial, Deme Karikios, Dariush Daneshvar, Rachael McCloy, Angela M Steinmann, Sandra O'Toole, Venessa Chin
Publikováno v:
Cancer Treatment and Research Communications, Vol 32, Iss , Pp 100576- (2022)
Background: Despite advances in immunotherapy and targeted therapy, platinum-based chemotherapy remains crucial for many patients with advanced non-small cell lung cancer (NSCLC). Resistance to platinum chemotherapy is common, and predictive biomarke
Externí odkaz:
https://doaj.org/article/c6f6f9eabdb24cf0bd7313e48f9a0c34
Autor:
Kamila A Marzec, Samuel Rogers, Rachael McCloy, Benjamin L Parker, David E James, D. Neil Watkins, Andrew Burgess
MASTL (microtubule-associated serine/threonine kinase-like) has emerged as a critical regulator of mitosis and as a potential oncogene in a variety of cancer types. To date, Arpp-19/ENSA are the only known substrates of MASTL. However, with the roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86c09b272eb026e0373aee9ad7de2588
https://doi.org/10.21203/rs.3.rs-1503557/v1
https://doi.org/10.21203/rs.3.rs-1503557/v1
Publikováno v:
Inside the Cell. 1:27-35
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 38
Entry into mitosis is driven by the activity of kinases, which phosphorylate over 7000 proteins on multiple sites. For cells to exit mitosis and segregate their genome correctly, these phosphorylations must be removed in a specific temporal order. Th