Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Racha Estephan"'
Autor:
Jacqueline Englander, Karen L Samples, Boris Arshava, Jeffrey M. Becker, Racha Estephan, Fred Naider
Publikováno v:
Biochemistry. 44:11795-11810
The yeast Saccharomyces cerevisiae alpha-factor pheromone receptor (Ste2p) was used as a model G protein-coupled receptor (GPCR). A 73-mer multidomain fragment of Ste2p (residues 267-339) containing the third extracellular loop, the seventh transmemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363672f9e0d5568f922096a1b3ecd4af
https://doi.org/10.1021/bi0507231
https://doi.org/10.1021/bi0507231
Autor:
Jacqueline Englander, Racha Estephan, V. V. Suresh babu, Enrique Arevalo, Fred Naider, Jeffrey M. Becker, Karen Samples
Publikováno v:
Biopolymers. 76:119-128
The yeast Saccharomyces cerevisiae undergoes cell fusion during sexual conjugation to form diploid cells. The haploids participating in this process signal each other through secreted peptide-mating factors (alpha-factor and a-factor) that are recogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ee52a1e60dd9cadb5e071fa97ecd42
https://doi.org/10.1002/bip.10567
https://doi.org/10.1002/bip.10567
Autor:
Nathan O'Connor, Alicia C. Reid, Thomas Maack, Diane Felsen, Racha Estephan, Rosalia Mora, Dix P. Poppas, Takashi Kameue, Jacqueline Brazin, Jie Chen, Arul Veerappan, Randi B. Silver, Surya V. Seshan
Mast cells are associated with inflammation and fibrosis. Whether they protect against or contribute to renal fibrosis is unclear. Based on our previous findings that mast cells can express and secrete active renin, and that angiotensin (ANG II) is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ff79be3311014c7e9d45cc7775ac00
https://europepmc.org/articles/PMC3251335/
https://europepmc.org/articles/PMC3251335/
Publikováno v:
Understanding Biology Using Peptides ISBN: 9780387265698
Introduction Biophysical studies on GPCRs are hampered by difficulty in crystallizing these molecules and conducting NMR on the intact receptor in the presence of vesicles. We have examined the biophysical properties of peptides representing fragment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f856fea99107cce42e3477d4478e6b7
https://doi.org/10.1007/978-0-387-26575-9_24
https://doi.org/10.1007/978-0-387-26575-9_24
Autor:
Racha Estephan, Kenichiro Koda, Federico Corti, Randi B. Silver, Daria Mochly-Rosen, Noel Yan-Ki Chan, Roberto Levi, Mariselis Salazar-Rodriguez
Publikováno v:
Circulation. 122(8)
Background— Renin released by ischemia/reperfusion from cardiac mast cells activates a local renin-angiotensin system (RAS). This exacerbates norepinephrine release and reperfusion arrhythmias (ventricular tachycardia and fibrillation), making RAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6305b9c3bf556f9e0f23ebfc3f6bf3
https://pubmed.ncbi.nlm.nih.gov/20697024
https://pubmed.ncbi.nlm.nih.gov/20697024
Autor:
Leah S, Cohen, Boris, Arshava, Racha, Estephan, Jacqueline, Englander, Melinda, Hauser, Jeffrey M, Becker, Fred, Naider
Publikováno v:
Advances in experimental medicine and biology. 611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a09662571f531a67a423828f1a203b0d
https://pubmed.ncbi.nlm.nih.gov/19400203
https://pubmed.ncbi.nlm.nih.gov/19400203
Autor:
Melinda Hauser, Boris Arshava, Jacquelinev Englander, Jeffrey M. Becker, Leah S. Cohen, Racha Estephan, Fred Naider
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387736563
Introduction There are thousands of protein structures in the databases that have been determined using X-ray crystallography and nuclear magnetic resonance spectroscopy. Despite the prevalence of integral membrane proteins, or IMPs (20-30% of the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::240577a79dd4c2d90242f791f558c3ff
https://doi.org/10.1007/978-0-387-73657-0_136
https://doi.org/10.1007/978-0-387-73657-0_136
Autor:
Heejung Kim, Jacqueline Englander, Marco Ceruso, Leah S. Cohen, Racha Estephan, Melinda Hauser, Oliver Zerbe, Boris Arshava, Jeffrey M. Becker, Fred Naider
Publikováno v:
Biopolymers. 90(2)
Fragments of G protein-coupled receptors (GPCRs) are widely used as models to investigate these polytopic integral-membrane, signal-transducing molecules, but have proven difficult to prepare in quantities necessary for NMR analyses. We report on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e14c8c467f291131e86aab87af3a7ae
https://pubmed.ncbi.nlm.nih.gov/18260136
https://pubmed.ncbi.nlm.nih.gov/18260136
Autor:
Alicia C. Reid, Racha Estephan, Randi B. Silver, Roberto Levi, Mariselis Salazar-Rodriguez, Nathan O'Connor, Maria Thadani-Mulero, Arul Veerappan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(4)
We previously reported that mast cells express renin, the rate-limiting enzyme in the renin–angiotensin cascade. We have now assessed whether mast cell renin release triggers angiotensin formation in the airway. In isolated rat bronchial rings, mas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f8a09567b042bb813b080b5f4ed352
https://pubmed.ncbi.nlm.nih.gov/18202178
https://pubmed.ncbi.nlm.nih.gov/18202178
Autor:
Jeffrey M. Becker, Jenifer Madeo, Enrique Arevalo, Boris Arshava, Mark E. Dumont, Fred Naider, Racha Estephan
Publikováno v:
Biopolymers. 71(4)
The alpha-factor receptor(Ste2p) is required for the sexual conjugation of the yeast Saccharomyces cerevisiae. Ste2p belongs to the G protein-coupled receptor (GPCR) family sharing a common heptahelical transmembrane structure. Biological synthesis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e494d82cc78e1872718fffadb980a7
https://pubmed.ncbi.nlm.nih.gov/14517901
https://pubmed.ncbi.nlm.nih.gov/14517901