Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Rabina, Mainali"'
1
Akademický článek
Itaconate stabilizes CPT1a to enhance lipid utilization during inflammation
Autor: Rabina Mainali, Nancy Buechler, Cristian Otero, Laken Edwards, Chia-Chi Key, Cristina Furdui, Matthew A Quinn
Publikováno v: eLife, Vol 12 (2024)
One primary metabolic manifestation of inflammation is the diversion of cis-aconitate within the tricarboxylic acid (TCA) cycle to synthesize the immunometabolite itaconate. Itaconate is well established to possess immunomodulatory and metabolic effe
Externí odkaz: https://doaj.org/article/dd51243f29f342b8ab5b57e0c54859d0
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2
Akademický článek
Itaconate and Its Derivatives Repress Early Myogenesis In Vitro and In Vivo
Autor: Tae Seok Oh, Damian C. Hutchins, Rabina Mainali, Kevin H. Goslen, Matthew A. Quinn
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects. While itaconate and its derivatives pose an attractive therapeutic option for t
Externí odkaz: https://doaj.org/article/1791641852a64c1e8ad7bde9e41bc54b
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3
Akademický článek
Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction
Autor: Rabina Mainali, Manal Zabalawi, David Long, Nancy Buechler, Ellen Quillen, Chia-Chi Key, Xuewei Zhu, John S Parks, Cristina Furdui, Peter W Stacpoole, Jennifer Martinez, Charles E McCall, Matthew A Quinn
Publikováno v: eLife, Vol 10 (2021)
Metabolic reprogramming between resistance and tolerance occurs within the immune system in response to sepsis. While metabolic tissues such as the liver are subjected to damage during sepsis, how their metabolic and energy reprogramming ensures surv
Externí odkaz: https://doaj.org/article/54dd853ae26241009d6cb06d0d6d3a95
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4
Akademický článek
A Newly Developed Synbiotic Yogurt Prevents Diabetes by Improving the Microbiome–Intestine–Pancreas Axis
Autor: Brandi Miller, Rabina Mainali, Ravinder Nagpal, Hariom Yadav
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 4, p 1647 (2021)
The prevalence of type 2 diabetes mellitus (T2D) is increasing worldwide, and there are no long-term preventive strategies to stop this growth. Emerging research shows that perturbations in the gut microbiome significantly contribute to the developme
Externí odkaz: https://doaj.org/article/c066db889dd6474983ffb7bf12fbb8a9
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6
Itaconate and Its Derivatives Repress Early Myogenesis
Autor: Tae Seok, Oh, Damian C, Hutchins, Rabina, Mainali, Kevin H, Goslen, Matthew A, Quinn
Publikováno v: Frontiers in immunology. 13
A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects. While itaconate and its derivatives pose an attractive therapeutic option for t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::69955c8a13b1e912a76acca857eda7d9
https://pubmed.ncbi.nlm.nih.gov/35265064
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7
A Newly Developed Synbiotic Yogurt Prevents Diabetes by Improving the Microbiome—Intestine—Pancreas Axis
Autor: Hariom Yadav, Ravinder Nagpal, Brandi Miller, Rabina Mainali
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1647, p 1647 (2021)
The prevalence of type 2 diabetes mellitus (T2D) is increasing worldwide, and there are no long-term preventive strategies to stop this growth. Emerging research shows that perturbations in the gut microbiome significantly contribute to the developme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2aa3abf43e09ddd8a45328211500957
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8
Itaconate and its derivatives repress C2C12 myogenesis
Autor: Tae Seok Oh, Matthew A. Quinn, Rabina Mainali, Damian C. Hutchins, Kevin H Goslen
A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects. While itaconate and its derivatives pose an attractive therapeutic option for t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5bd0b24b0cbf7056cb20d5731a31872a
https://doi.org/10.1101/2021.02.01.429228
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9
Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction
Autor: Xuewei Zhu, Cristina M. Furdui, Matthew A. Quinn, Peter W. Stacpoole, Ellen E. Quillen, Nancy L. Buechler, John S. Parks, Charles E. McCall, Jennifer Martinez, Manal Zabalawi, David L. Long, Rabina Mainali, Chia-Chi C. Key
Publikováno v: eLife, Vol 10 (2021)
eLife
Dramatic metabolic reprogramming between an anabolic resistance and catabolic tol-erance state occurs within the immune system in response to systemic infection with the sepsis syndrome. While metabolic tissues such as the liver are subject to end-or
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076a20fa5335306b23886b95e0365e8b
https://elifesciences.org/articles/64611
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