Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rabih Gabriel"'
Autor:
Wayne C. Widdison, Ravi V.J. Chari, John M. Lambert, Hans K. Erickson, Qifeng Qiu, Rui Wu, Paulin Salomon, Rabih Gabriel, Anna Skaletskaya, Juliet A. Costoplus, Karen Veale, Leanne Lanieri, Jennifer A. Coccia, Gregory E. Jones, Ling Dong, Nathan Fishkin, E. Erica Hong, Katharine C. Lai, Yelena V. Kovtun, Jose Ponte, Yulius Y. Setiady, Rajeeva Singh
Supplementary Methods (S1-S3). Supplementary Method S1: Synthesis of di-, tri-, tetra-glycyl, and valine-citrulline-glycine peptide linkers and catabolites. Supplementary Method S2: Test of in vitro cytotoxicity, cell-cycle inhibition, and bystander
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b6d4b4f9c44ca6353724746b9d8c98
https://doi.org/10.1158/1535-7163.22503028.v1
https://doi.org/10.1158/1535-7163.22503028.v1
Autor:
Wayne C. Widdison, Ravi V.J. Chari, John M. Lambert, Hans K. Erickson, Qifeng Qiu, Rui Wu, Paulin Salomon, Rabih Gabriel, Anna Skaletskaya, Juliet A. Costoplus, Karen Veale, Leanne Lanieri, Jennifer A. Coccia, Gregory E. Jones, Ling Dong, Nathan Fishkin, E. Erica Hong, Katharine C. Lai, Yelena V. Kovtun, Jose Ponte, Yulius Y. Setiady, Rajeeva Singh
Supplementary Table S1: Amounts of catabolites generated upon treatment of cancer cells with CX and SMCC ADCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1bbdc7f0c64a9492add2e343489150
https://doi.org/10.1158/1535-7163.22503025.v1
https://doi.org/10.1158/1535-7163.22503025.v1
Autor:
Wayne C. Widdison, Ravi V.J. Chari, John M. Lambert, Hans K. Erickson, Qifeng Qiu, Rui Wu, Paulin Salomon, Rabih Gabriel, Anna Skaletskaya, Juliet A. Costoplus, Karen Veale, Leanne Lanieri, Jennifer A. Coccia, Gregory E. Jones, Ling Dong, Nathan Fishkin, E. Erica Hong, Katharine C. Lai, Yelena V. Kovtun, Jose Ponte, Yulius Y. Setiady, Rajeeva Singh
Supplementary Figures (S1-S4). Supplementary Figure S1: In vitro cytotoxic activities of tetraglycyl (Gly4), triglycyl (Gly3), diglycyl (Gly2), and valine-citrulline-glycine (VCG)-linked anti-EGFR ADCs and a triglycyl-linked non-binding antibody ADC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dfc500f111def02ff705de4c140fe0
https://doi.org/10.1158/1535-7163.22503031.v1
https://doi.org/10.1158/1535-7163.22503031.v1
Autor:
Rui Wu, Leanne Lanieri, Qifeng Qiu, Ravi V. J. Chari, Juliet Costoplus, Yulius Setiady, Rabih Gabriel, E. Erica Hong, Ling Dong, Yelena Kovtun, Nathan Fishkin, Karen Veale, Gregory E. Jones, Wayne C. Widdison, Rajeeva Singh, John M. Lambert, Jose F. Ponte, Katharine C. Lai, Paulin Salomon, Jennifer A. Coccia, Anna Skaletskaya, Hans K. Erickson
Publikováno v:
Molecular cancer therapeutics. 15(6)
A triglycyl peptide linker (CX) was designed for use in antibody–drug conjugates (ADC), aiming to provide efficient release and lysosomal efflux of cytotoxic catabolites within targeted cancer cells. ADCs comprising anti-epithelial cell adhesion mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa47784e9c15460281c49bb05ab3003a
https://pubmed.ncbi.nlm.nih.gov/27197308
https://pubmed.ncbi.nlm.nih.gov/27197308
Autor:
Whiteman, Kathleen R., Johnson, Holly A., Mayo, Michele F., Audette, Charlene A., Carrigan, Christina N., Labelle, Alyssa, Zukerberg, Lawrence, Lambert, John M., Lutz, Robert J.
Publikováno v:
mAbs; Mar/Apr2014, Vol. 6 Issue 2, p556-566, 11p
Autor:
Doyle, Dara
Publikováno v:
Business & Finance; 08/20/98, Vol. 34 Issue 42, p58, 1p, 3 Color Photographs