Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rabih El- Merahbi"'
Autor:
Anastasia Georgiadi, Valeria Lopez-Salazar, Rabih El- Merahbi, Rhoda Anane Karikari, Xiaochuan Ma, André Mourão, Katarina Klepac, Lea Bühler, Ana Jimena Alfaro, Isabell Kaczmarek, Adam Linford, Madeleen Bosma, Olga Shilkova, Olli Ritvos, Nobuhiro Nakamura, Shigehisa Hirose, Maximilian Lassi, Raffaele Teperino, Juliano Machado, Marcel Scheideler, Arne Dietrich, Arie Geerlof, Annette Feuchtinger, Andreas Blutke, Katrin Fischer, Timo Dirk Müller, Katharina Kessler, Torsten Schöneberg, Doreen Thor, Silke Hornemann, Michael Kruse, Peter Nawroth, Olga Pivovarova-Ramich, Andreas Friedrich Hermann Pfeiffer, Michael Sattler, Matthias Blüher, Stephan Herzig
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
The soluble bioactive form of the transmembrane protein fibronectin type III domain containing 4 (sFNDC4) has anti-inflammatory effects and improves insulin sensitivity. Here the authors show that liver derived sFNDC4 signals through adipose tissue G
Externí odkaz:
https://doaj.org/article/899459e9671c4eeca6889de131d50098
Autor:
Till Karwen, Katarzyna Kolczynska‐Matysiak, Carina Gross, Mona C Löffler, Mike Friedrich, Angel Loza‐Valdes, Werner Schmitz, Magdalena Wit, Filip Dziaczkowski, Andrei Belykh, Jonathan Trujillo‐Viera, Rabih El‐Merahbi, Carsten Deppermann, Sameena Nawaz, Benoit Hastoy, Agnieszka Demczuk, Manuela Erk, Mariusz R Wieckowski, Patrik Rorsman, Katrin G Heinze, David Stegner, Bernhard Nieswandt, Grzegorz Sumara
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 9, Pp 1-23 (2023)
Abstract Hyperreactive platelets are commonly observed in diabetic patients indicating a potential link between glucose homeostasis and platelet reactivity. This raises the possibility that platelets may play a role in the regulation of metabolism. P
Externí odkaz:
https://doaj.org/article/974cd37e10194d4682e8df439ae20f8d
Autor:
Angel Loza-Valdes, Rabih El-Merahbi, Toufic Kassouf, Agnieszka Demczuk, Saskia Reuter, Jonathan Trujillo Viera, Till Karwen, Minhe Noh, Mona C. Löffler, Rafael Romero-Becerra, Jorge L. Torres, Miguel Marcos, Guadalupe Sabio, Urszula Wojda, Grzegorz Sumara
Publikováno v:
Biochemical and biophysical research communications. 612
Kinases represent one of the largest druggable families of proteins. Importantly, many kinases are aberrantly activated/de-activated in multiple organs during obesity, which contributes to the development of diabetes and associated diseases. Previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bdabd99c152f783d9afc301f69710c
https://pubmed.ncbi.nlm.nih.gov/35523049
https://pubmed.ncbi.nlm.nih.gov/35523049
Autor:
Jonathan Trujillo Viera, Rabih El-Merahbi, Bernhard Nieswandt, David Stegner, Grzegorz Sumara
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157607 (2016)
Obesity is a major risk factor predisposing to the development of peripheral insulin resistance and type 2 diabetes (T2D). Elevated food intake and/or decreased energy expenditure promotes body weight gain and acquisition of adipose tissue. Number of
Externí odkaz:
https://doaj.org/article/dc97c62dccb448258f2a0054c4661ea4
Autor:
Laura Bernhardt, Marcus Dittrich, Rabih El-Merahbi, Antoine-Emmanuel Saliba, Tobias Müller, Grzegorz Sumara, Jörg Vogel, Stefanie Nichols-Burns, Megan Mitchell, Thomas Haaf, Nady El Hajj
Publikováno v:
Scientific reports
England
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
England
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Paternal obesity is known to have a negative impact on the male’s reproductive health as well as the health of his offspring. Although epigenetic mechanisms have been implicated in the non-genetic transmission of acquired traits, the effect of pate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06255c46b1cebc85ecaecc72b8d428ab
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139939 (2015)
The placenta, a transient organ in human, is essential for pregnancy maintenance and for fetal growth and development. Trophoblast and stromal cells are the main cell types present in human placenta. Trophoblast cells are present in different subtype
Externí odkaz:
https://doaj.org/article/b106c05aa592446cb9f19227bfa231f5
Autor:
Maria Troullinaki, Valeria Lopez Salazar, Maria Rohm, Rhoda Anane Karikari, Lun Li, Moya Wu, Tobias Wiedemann, Anastasia Georgiadi, Rabih El-Merahbi, Alina Walth, Stephan Herzig, Manuel Gil Lozano
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 35
Withdrawal: Valeria Lopez Salazar, Rhoda Anane Karikari, Lun Li, Rabih El-Merahbi, Maria Troullinaki, Moya Wu, Tobias Wiedemann, Alina Walth, Manuel Gil Lozano, Maria Rohm, Stephan Herzig, Anastasia Georgiadi. Adipocyte Deletion of ADAM17 Leads to In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf8916eb8b8a2e07dbbe8efef619cb5
https://pubmed.ncbi.nlm.nih.gov/34318951
https://pubmed.ncbi.nlm.nih.gov/34318951
Autor:
Rabih El-Merahbi, Yen-Nien Liu, Assaad Eid, Georges Daoud, Leina Hosry, Alissar Monzer, Tarek H Mouhieddine, Aline Hamade, Fadia Najjar, Wassim Abou-Kheir
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112453 (2014)
Cancer stem cells (CSCs), including those of advanced prostate cancer, are a suggested reason for tumor resistance toward conventional tumor therapy. Therefore, new therapeutic agents are urgently needed for targeting CSCs. Despite the minimal unders
Externí odkaz:
https://doaj.org/article/dce918682dea43c9b3dd4328617fa629
Autor:
Torsten Schöneberg, Arie Geerlof, Michael Kruse, Juliano Machado, Maximilian Lassi, Michael Sattler, Annette Feuchtinger, Adam Linford, Katharina Kessler, Shigehisa Hirose, Lea Bühler, Arne Dietrich, Rabih El Merahbi, Xiaochuan Ma, Katrin Fischer, Ana Jimena Alfaro, Matthias Blüher, Andreas Pfeiffer, Madeleen Bosma, Rhoda Anane Karikari, Nobuhiro Nakamura, Doreen Thor, Peter P. Nawroth, Olli Ritvos, Timo Dirk Müller, Andreas Blutke, Valeria Lopez-Salazar, Silke Hornemann, Raffaele Teperino, Marcel Scheideler, Stephan Herzig, Isabell Kaczmarek, Olga Pivovarova-Ramich, Olga Shilkova, André Mourão, Anastasia Georgiadi, Katarina Klepac
Publikováno v:
Nat. Commun. 12:2999 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
The proper functional interaction between different tissues represents a key component in systemic metabolic control. Indeed, disruption of endocrine inter-tissue communication is a hallmark of severe metabolic dysfunction in obesity and diabetes. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6becfedda585f0f475538203b2f24cc4
https://www.repository.cam.ac.uk/handle/1810/322750
https://www.repository.cam.ac.uk/handle/1810/322750
Publikováno v:
EMBO Molecular Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::c06a64dc67ce8af2d718f4daf85efcac