Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rabie Jouni"'
Autor:
Richard Vollenberg, Rabie Jouni, Peter A. A. Norris, Monika Burg-Roderfeld, Nina Cooper, Mathias J. Rummel, Gregor Bein, Irene Marini, Behnaz Bayat, Richard Burack, Alan H. Lazarus, Tamam Bakchoul, Ulrich J. Sachs
Publikováno v:
Haematologica, Vol 104, Iss 6 (2019)
Platelet autoantibody-induced platelet clearance represents a major pathomechanism in immune thrombocytopenia (ITP). There is growing evidence for clinical differences between anti-glycoprotein IIb/IIIa and anti-glycoprotein Ib/IX mediated ITP. Glyco
Externí odkaz:
https://doaj.org/article/c7970fdffc1e498880f07c0ac1c89172
Autor:
Irene Marini, Konstanze Aurich, Rabie Jouni, Stefanie Nowak-Harnau, Oliver Hartwich, Andreas Greinacher, Thomas Thiele, Tamam Bakchoul
Publikováno v:
Haematologica, Vol 104, Iss 1 (2019)
Platelet transfusion has become essential therapy in modern medicine. Although the clinical advantage of platelet transfusion has been well established, adverse reactions upon transfusion, especially transmission of bacterial infection, still represe
Externí odkaz:
https://doaj.org/article/09af8901237e4b588196fb2facd83d42
Publikováno v:
Journal of Thrombosis and Haemostasis. 14:1685-1695
Protamine is widely used in medicine as a rapidly-acting antidote to heparin, particularly for reversing heparin anticoagulation after cardiac surgery. Protamine is also used as a stabilizing additive to certain preparations of insulin. Recent report
Autor:
Rabie Jouni, Heike Zöllner, Julia Fuhrmann, Tamam Bakchoul, Andreas Greinacher, Jan Wesche, Jenny Alex
Publikováno v:
Transfusion. 56:1370-1376
BACKGROUND The NOD/SCID mouse model is a unique and sophisticated method to study the survival of human platelets (PLTs) in vivo. Meanwhile, several research groups adopted this model to analyze a wide range of PLT antibodies. Differences exist betwe
Autor:
S. Schellong, A. Khadour, Andreas Greinacher, A. Heinken, Tamam Bakchoul, Simon Panzer, Heike Zöllner, Rabie Jouni, M. J. ten Berg, Jan Wesche, L. Janzen
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 15(1)
Essentials Protamine (PRT) is used to stabilize insulin in neutral protamine Hagedorn (NPH) insulin. The interaction between NPH-insulin, anti-PRT/heparin antibodies and platelets was investigated. Anti-PRT/heparin antibodies activate platelets in pr
Autor:
Mathias J. Rummel, Monika Burg-Roderfeld, Richard Vollenberg, Gregor Bein, Peter A. A. Norris, Ulrich J. Sachs, Nina Cooper, Tamam Bakchoul, Rabie Jouni, Alan H. Lazarus, Irene Marini
Publikováno v:
Blood. 132:1141-1141
Immune thrombocytopenia (ITP) results from autoimmunization against platelet antigens. Autoantibodies (aabs) are considered to represent a major mechanism of thrombocytopenia in ITP by inducing platelet clearance from the circulation. Several lines o
Autor:
Andreas Greinacher, Tamam Bakchoul, Matthias Hundt, Krystin Krauel, Hansjörg Schwertz, Rabie Jouni, Inga Jensch, Julia van der Linde, Andreas Koster, Annika Schulze, Sixten Selleng, Christine Hackbarth, Bernhard Hietkamp
Publikováno v:
Thrombosis and haemostasis. 115(4)
SummaryAnti-platelet factor 4 (PF4)/heparin antibodies are not only the cause of heparin-induced thrombocytopenia but might also play a role in the antibacterial host defence. Recently, marginal zone (MZ) B cells were identified to be crucial for ant
Autor:
Sven Brandt, Anne Grotevendt, Jan Wesche, Ulrich J. Sachs, Tamam Bakchoul, Heike Zöllner, Rabie Jouni, Ahmad Khadour, Mihaela Delcea, Krystin Krauel, Hansjörg Schwertz, Andreas Greinacher
Publikováno v:
Thrombosis and haemostasis. 115(2)
SummaryProtamine (PRT) is the standard drug to neutralise heparin. PRT/heparin complexes induce an immune response similar to that observed in heparin-induced thrombocytopenia (HIT). Partially desulfated heparin (ODSH) was shown to interfere with ant
Autor:
Julia, Fuhrmann, Rabie, Jouni, Jenny, Alex, Heike, Zöllner, Jan, Wesche, Andreas, Greinacher, Tamam, Bakchoul
Publikováno v:
Transfusion. 56(6)
The NOD/SCID mouse model is a unique and sophisticated method to study the survival of human platelets (PLTs) in vivo. Meanwhile, several research groups adopted this model to analyze a wide range of PLT antibodies. Differences exist between the rese