Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Rabia A. Gilani"'
Zoledronic acid, a third-generation bisphosphonate, has been shown to reduce cell migration, invasion, and metastasis. However, the effects of zoledronic acid on the epithelial–mesenchymal transition (EMT), a cellular process essential to the metas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa7cd154929ad21aec103104266937a4
https://doi.org/10.1158/1535-7163.c.6536677.v1
https://doi.org/10.1158/1535-7163.c.6536677.v1
PDF file - 195K, Zoledronic acid prevents inhibits the number of existing mammospheres.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa280647bfa462d67df4c557765b3e4
https://doi.org/10.1158/1535-7163.22501108
https://doi.org/10.1158/1535-7163.22501108
PDF file - 52K, Zoledronic acid inactivates NFκB, and inhibits interactions between RelA and the Twist promoter and Twist and the BMI-1 promoter in Hs578t cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24811edf842fcbf343f2be17d183d95b
https://doi.org/10.1158/1535-7163.22501105.v1
https://doi.org/10.1158/1535-7163.22501105.v1
Autor:
Matthew B. Soellner, Sofia D. Merajver, Kelley M. Kidwell, Carrie R. Graveel, Frank E. Kwarcinski, Michael E. Steffey, Kristoffer R. Brandvold, Michele L. Dziubinski, Eric J. Lachacz, Li Wei Bao, Sameer Phadke, Rabia A. Gilani
Kinome-wide profiling data of UM-164 and dasatinib in MDA-MB 231 lysate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155184a4bb1eca98285b750c77a65d11
https://doi.org/10.1158/1078-0432.22458360.v1
https://doi.org/10.1158/1078-0432.22458360.v1
Autor:
Matthew B. Soellner, Sofia D. Merajver, Kelley M. Kidwell, Carrie R. Graveel, Frank E. Kwarcinski, Michael E. Steffey, Kristoffer R. Brandvold, Michele L. Dziubinski, Eric J. Lachacz, Li Wei Bao, Sameer Phadke, Rabia A. Gilani
Legends associated with Supplementary Figures S1-S12.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ea25bd453398a21c3339a640b08eeb
https://doi.org/10.1158/1078-0432.22458369.v1
https://doi.org/10.1158/1078-0432.22458369.v1
Autor:
Matthew B. Soellner, Sofia D. Merajver, Kelley M. Kidwell, Carrie R. Graveel, Frank E. Kwarcinski, Michael E. Steffey, Kristoffer R. Brandvold, Michele L. Dziubinski, Eric J. Lachacz, Li Wei Bao, Sameer Phadke, Rabia A. Gilani
Supplementary Figure S1. Biochemical data for UM-164 and dasatinib. Supplementary Figure S2. Western blots showing the expression of P-Src, P-EGFR and P-p38MAPK in selected TNBC cell lines. Supplementary Figure S3. UM-164 is a dual c-Src/p38 kinase i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c155461b3df2a17baaf7e18851ad46
https://doi.org/10.1158/1078-0432.22458366
https://doi.org/10.1158/1078-0432.22458366
Autor:
Matthew B. Soellner, Sofia D. Merajver, Kelley M. Kidwell, Carrie R. Graveel, Frank E. Kwarcinski, Michael E. Steffey, Kristoffer R. Brandvold, Michele L. Dziubinski, Eric J. Lachacz, Li Wei Bao, Sameer Phadke, Rabia A. Gilani
Detailed experimental information for: Cell cycle analysis; Dose response studies; Western blot analyses; 3D cell culture; Bead motility assay; Cell invasion assays; General synthetic methods; Synthesis of UM-164.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e087ed54f8e25684bd39a255acc33aa
https://doi.org/10.1158/1078-0432.22458363.v1
https://doi.org/10.1158/1078-0432.22458363.v1
Autor:
Matthew B. Soellner, Sofia D. Merajver, Kelley M. Kidwell, Carrie R. Graveel, Frank E. Kwarcinski, Michael E. Steffey, Kristoffer R. Brandvold, Michele L. Dziubinski, Eric J. Lachacz, Li Wei Bao, Sameer Phadke, Rabia A. Gilani
Purpose: c-Src has been shown to play a pivotal role in breast cancer progression, metastasis, and angiogenesis. In the clinic, however, the limited efficacy and high toxicity of existing c-Src inhibitors have tempered the enthusiasm for targeting c-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476398550000e7e3032d4769fdb8d302
https://doi.org/10.1158/1078-0432.c.6523923
https://doi.org/10.1158/1078-0432.c.6523923
Autor:
Xu Cheng, Y-M Wu, Matthew B. Soellner, Robinson, Arul M. Chinnaiyan, Aki Morikawa, Eric J. Lachacz, Rabia A. Gilani, Robert J. Lonigro, K McMurray, Daniel F. Hayes, Jason Heth, Jeffrey B. Smerage, Dafydd G. Thomas, Norah Lynn Henry, Sofia D. Merajver
Publikováno v:
Cancer Research. 79:PD9-12
Background: Breast cancer brain metastasis (BM) is an area of unmet need in metastatic breast cancer patients. Novel therapeutic interventions to help prevent and treat BM are warranted. We conducted integrative molecular profiling of BM and matched