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Akademický článek

Impact of bronchoalveolar lavage from influenza A virus diseased pigs on neutrophil functions and growth of co-infecting pathogenic bacteria

Autor: Simon Lassnig, Isabel Hennig-Pauka, Marta C. Bonilla, Matthias Mörgelin, Rabea Imker, Maren von Köckritz-Blickwede, Nicole de Buhr

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionInfluenza A viruses (IAVs) infect the respiratory tract of mainly humans, poultry, and pigs. Co-infections with pathogenic lung bacteria are a common event and contribute to the severity of disease progression. Neutrophils are a major cel

Externí odkaz: https://doaj.org/article/d81fb64c6feb458184c9dd54d4c7dcbb

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Akademický článek

Insights Into Immunothrombotic Mechanisms in Acute Stroke due to Vaccine-Induced Immune Thrombotic Thrombocytopenia

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

During the COVID-19 pandemic, vaccination is the most important countermeasure. Pharmacovigilance concerns however emerged with very rare, but potentially disastrous thrombotic complications following vaccination with ChAdOx1. Platelet factor-4 antib

Externí odkaz: https://doaj.org/article/d9e975e6804a4bf5bf394f03faa7c7cc

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Akademický článek

Studying the Interaction of Neutrophils and Glaesserella Parasuis Indicates a Serotype Independent Benefit from Degradation of NETs

Autor: Marta C. Bonilla, Simon Lassnig, Andrea Obando Corella, Rabea Imker, Peter Valentin-Weigand, Maren von Köckritz-Blickwede, Anne-Marie Luther, Isabel Hennig-Pauka, Nicole de Buhr

Publikováno v: Pathogens, Vol 11, Iss 8, p 880 (2022)

Glaesserella (G.) parasuis is one of the most important porcine pathogens causing Glaesser’s disease. Neutrophil granulocytes are the major counteracting cell type of the innate immune system, which contribute to the host defense by phagocytosis or

Externí odkaz: https://doaj.org/article/435aa69d77db4f84b2f36c5a4a616ec9

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Endogenous Deoxyribonuclease Activity and Cell-Free Deoxyribonucleic Acid in Acute Ischemic Stroke: A Cohort Study

Autor: Gerrit M. Grosse, Nicole Blume, Omar Abu-Fares, Friedrich Götz, Johanna Ernst, Andrei Leotescu, Maria M. Gabriel, Till van Gemmeren, Hans Worthmann, Ralf Lichtinghagen, Rabea Imker, Christine S. Falk, Karin Weissenborn, Ramona Schuppner, Nicole de Buhr

Publikováno v: Stroke. 53:1235-1244

Background: Cell-free DNA (cfDNA) and endogenous deoxyribonuclease activity are opposing mediators and might influence the inflammatory response following acute ischemic stroke. In this cohort study, we investigated the relation between these markers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3e24a1de7decc600d3ad964c6f1a53
https://doi.org/10.1161/strokeaha.121.036299

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Studying the Interaction of Neutrophils and Glaesserella Parasuis Indicates a Serotype Independent Benefit from Degradation of NETs

Autor: Buhr, Marta C. Bonilla, Simon Lassnig, Andrea Obando Corella, Rabea Imker, Peter Valentin-Weigand, Maren von Köckritz-Blickwede, Anne-Marie Luther, Isabel Hennig-Pauka, Nicole de

Publikováno v: Pathogens; Volume 11; Issue 8; Pages: 880

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::31e66910310755705e9eb601acd6a843

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Akademický článek

From Stable to Lab—Investigating Key Factors for Sudden Deaths Caused by Streptococcus suis

Autor: Isabel Hennig-Pauka, Rabea Imker, Leonie Mayer, Michael Brügmann, Christiane Werckenthin, Heike Weber, Andrea Menrath, Nicole de Buhr

Publikováno v: Pathogens, Vol 8, Iss 4, p 249 (2019)

Swine stocks are endemically infected with the major porcine pathogen Streptococcus (S.) suis. The factors governing the transition from colonizing S. suis residing in the tonsils and the exacerbation of disease have not yet been elucidated. We analy

Externí odkaz: https://doaj.org/article/fce4861bf2f74a32bf86f2c6b841b01b

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Methylprednisolone Induces Extracellular Trap Formation and Enhances Bactericidal Effect of Canine Neutrophils

Autor: Nicole Steffensen, Rabea Imker, Simon Lassnig, Marcus Fulde, Johanna C. Rieder, Nicole de Buhr

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7734, p 7734 (2021)

Methylprednisolone is a glucocorticoid and can negatively influence immune defense mechanisms. During bacterial infections in the dog, neutrophils infiltrate infected tissue and mediate antimicrobial effects with different mechanisms such as phagocyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3a71eb637ff253f927b0de89630624

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Characterization of Tailor-Made Copolymers of Oligo(ethylene glycol) Methyl Ether Methacrylate and N,N-Dimethylaminoethyl Methacrylate as Nonviral Gene Transfer Agents: Influence of Macromolecular Structure on Gene Vector Particle Properties and Transfection Efficiency

Autor: Özgür Akdemir, Monika M. Golas, Bjoern Sander, Senta Üzgün, Holger Stark, Christof Maucksch, Günther Hasenpusch, Jean-François Lutz, Rabea Imker, Carsten Rudolph

Publikováno v: Biomacromolecules
Uzgün, S, Akdemir, O, Hasenpusch, G, Maucksch, C, Golas, M M, Sander, B, Stark, H, Imker, R, Lutz, J-F & Rudolph, C 2010, ' Characterization of tailor-made copolymers of oligo(ethylene glycol) methyl ether methacrylate and N,N-dimethylaminoethyl methacrylate as nonviral gene transfer agents: influence of macromolecular structure on gene vector particle properties and transfection efficiency ', Biomacromolecules, vol. 11, no. 1, pp. 39-50 . https://doi.org/10.1021/bm9008759

Udgivelsesdato: 2010-Jan-11 Oligo(ethylene glycol) methyl ether methacrylates (OEGMA) of various chain lengths (i.e., 9, 23, or 45 EG units) and N,N-dimethylaminoethyl methacrylate (DMAEMA) were copolymerized by atom transfer radical polymerization (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05affccebe49013fa7e39d9aa5113202
https://doi.org/10.1021/bm9008759

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